Box-Behnken study design for optimization of bicalutamide-loaded nanostructured lipid carrier: Stability assessment

Pharmaceutical Development and Technology

Volumn 20, Issue 5, 2015, Pages 608-618

  Kudarha, Ritu ^a   Dhas, Namdev L ^a   Pandey, Abhijeet ^b   Belgamwar, Veena S ^c   Ige, Pradum P ^a  

^a Shirpur Pharmaceutics   (India)

^b H R PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

^c RTM NAGPUR UNIVERSITY   (India)

Author keywords

Bicalutamide; design space; hot high pressure homogenization; quality attributes; robustness; stability

Indexed keywords

ALBUMIN; BICALUTAMIDE; LIPID; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; PHOSPHATIDYLCHOLINE; PLASMA PROTEIN; UNCLASSIFIED DRUG; ANILIDE; ANTIANDROGEN; ANTINEOPLASTIC AGENT; DRUG CARRIER; NANOMATERIAL; NITRILE; TOLUENESULFONIC ACID DERIVATIVE;

ADULT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; ERYTHROCYTE; EXCIPIENT COMPATIBILITY; FREEZE DRYING; HEMOLYSIS; LIPID BLOOD LEVEL; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRESSURE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN STABILITY; RAT; RESPONSE SURFACE METHOD; SCANNING ELECTRON MICROSCOPY; STORAGE; X RAY DIFFRACTION; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; ULTRASTRUCTURE;

ANDROGEN ANTAGONISTS; ANILIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD PROTEINS; DRUG CARRIERS; DRUG STABILITY; HEMOLYSIS; LIPIDS; NANOSTRUCTURES; NITRILES; PARTICLE SIZE; RATS; TOSYL COMPOUNDS;

EID: 84937206354     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2014.908305     Document Type: Article

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