In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain

Drug Development and Industrial Pharmacy

Volumn 37, Issue 6, 2011, Pages 737-746

  Montenegro, Lucia ^a   Campisi, Agata ^a   Sarpietro, Maria Grazia ^a   Carbone, Claudia ^a   Acquaviva, Rosaria ^a   Raciti, Giuseppina ^a   Puglisi, Giovanni ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

blood brain barrier; colloidal carrier; drug delivery; in vitro antioxidant activity; In vitro release

Indexed keywords

IDEBENONE; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SOLID LIPID NANOPARTICLE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN; BRAIN CORTEX; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; MICROEMULSION; NEWBORN; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; ASTROCYTES; BLOOD-BRAIN BARRIER; CEREBRAL CORTEX; CETOMACROGOL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; ETHYLENE GLYCOLS; FATTY ALCOHOLS; GLYCERIDES; NANOPARTICLES; PALMITATES; PARTICLE SIZE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SURFACE-ACTIVE AGENTS; TISSUE DISTRIBUTION; UBIQUINONE;

EID: 79955670424     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.539231     Document Type: Article

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