메뉴 건너뛰기




Volumn 2, Issue 2, 2009, Pages 152-171

Nanostructured lipid carriers and their application in drug delivery

Author keywords

Applications; Characterisation; Nanostructured lipid carriers; NLC; Production techniques; SLN; Solid lipid nanoparticles

Indexed keywords

APPLICATIONS; NANOPARTICLES; TARGETED DRUG DELIVERY;

EID: 71049184592     PISSN: 17526418     EISSN: 17526426     Source Type: Journal    
DOI: 10.1504/IJBET.2009.022913     Document Type: Article
Times cited : (16)

References (76)
  • 1
    • 0032708458 scopus 로고    scopus 로고
    • High resolution determination of 20 nm colloidal gold particles by sedimentation field flow fractionation
    • Anger, S., Caldwell, K., Niehus, H. and Muller, R.H. (1999) 'High resolution determination of 20 nm colloidal gold particles by sedimentation field flow fractionation', Pharm. Res., Vol. 16, pp.1743-1747.
    • (1999) Pharm. Res , vol.16 , pp. 1743-1747
    • Anger, S.1    Caldwell, K.2    Niehus, H.3    Muller, R.H.4
  • 2
    • 1942498889 scopus 로고    scopus 로고
    • Cyclosporine nanoparticulate lipospheres for oral administration
    • Bekerman, T., Golenser, J. and Domb, A. (2004) 'Cyclosporine nanoparticulate lipospheres for oral administration', J. Pharm Sci. Vol. 93, No. 5, pp.1264-1270.
    • (2004) J. Pharm Sci , vol.93 , Issue.5 , pp. 1264-1270
    • Bekerman, T.1    Golenser, J.2    Domb, A.3
  • 3
    • 28244474457 scopus 로고    scopus 로고
    • Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy
    • Borgia, S.L., Regehly, M., Sivaramakrishnan, R., Mehnert, W., Korting, H.C., Danker, K., Roder, B., Kramer, K.D. and Schafer-Korting, M. (2005) 'Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy', J. Control. Release, Vol. 110, pp.151-163.
    • (2005) J. Control. Release , vol.110 , pp. 151-163
    • Borgia, S.L.1    Regehly, M.2    Sivaramakrishnan, R.3    Mehnert, W.4    Korting, H.C.5    Danker, K.6    Roder, B.7    Kramer, K.D.8    Schafer-Korting, M.9
  • 4
    • 0029876015 scopus 로고    scopus 로고
    • Crystallization tendency and polymorphic transitions in triglycerides nanoparticles
    • Bunjes, H., Westesen, K. and Koch, M.H.J. (1996) 'Crystallization tendency and polymorphic transitions in triglycerides nanoparticles', Int. J. Pharm., Vol. 129, pp.159-173.
    • (1996) Int. J. Pharm , vol.129 , pp. 159-173
    • Bunjes, H.1    Westesen, K.2    Koch, M.H.J.3
  • 5
    • 0037093721 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin
    • Cavalli, R., Gasco, M.R., Chetoni, P., Burgalassi, S. and Saettone, M.F. (2002) 'Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin', Int. J. Pharm., Vol. 238, pp.241-245.
    • (2002) Int. J. Pharm , vol.238 , pp. 241-245
    • Cavalli, R.1    Gasco, M.R.2    Chetoni, P.3    Burgalassi, S.4    Saettone, M.F.5
  • 6
    • 0242684665 scopus 로고    scopus 로고
    • Duodenal administration of SLN loaded with different percentages of tobramycin
    • Cavalli, R., Bargoni, A., Podio, V., Muntoni, E., Zara, G.P. and Gasco, M.R. (2003) 'Duodenal administration of SLN loaded with different percentages of tobramycin', J. Pharm. Sci., Vol. 92, No. 5, pp.1085-1094.
    • (2003) J. Pharm. Sci , vol.92 , Issue.5 , pp. 1085-1094
    • Cavalli, R.1    Bargoni, A.2    Podio, V.3    Muntoni, E.4    Zara, G.P.5    Gasco, M.R.6
  • 7
    • 26444523079 scopus 로고    scopus 로고
    • Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry
    • Castelli, F., Puglia, C., Sarpietro, M.G., Rizza, L. and Bonina, F. (2005) 'Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry', Int. J. Pharm., Vol. 304, Nos. 1-2, pp.231-238.
    • (2005) Int. J. Pharm , vol.304 , Issue.1-2 , pp. 231-238
    • Castelli, F.1    Puglia, C.2    Sarpietro, M.G.3    Rizza, L.4    Bonina, F.5
  • 8
    • 29244436380 scopus 로고    scopus 로고
    • Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
    • Chen, H., Chang, X., Du, D., Liu, W., Liu, J., Weng, T., Yang, Y., Xu, H. and Yang, X. (2006) 'Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting', J. Control. Release, Vol. 110, No. 2, pp.296-306.
    • (2006) J. Control. Release , vol.110 , Issue.2 , pp. 296-306
    • Chen, H.1    Chang, X.2    Du, D.3    Liu, W.4    Liu, J.5    Weng, T.6    Yang, Y.7    Xu, H.8    Yang, X.9
  • 9
    • 0036153138 scopus 로고    scopus 로고
    • Production of solid lipid nanoparticles (SLN): Scaling up feasibilities
    • Dingler, A. and Gohla, S. (2002) 'Production of solid lipid nanoparticles (SLN): Scaling up feasibilities', J. Microencapsul., Vol. 19, No. 1, pp.11-16.
    • (2002) J. Microencapsul , vol.19 , Issue.1 , pp. 11-16
    • Dingler, A.1    Gohla, S.2
  • 10
    • 17444418329 scopus 로고    scopus 로고
    • Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures
    • Garcia-Fuentes, M., Alonso, M.J. and Torres, D. (2005a) 'Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures', J. Colloid Interface Sci., Vol. 285, No. 2, pp.590-598.
    • (2005) J. Colloid Interface Sci , vol.285 , Issue.2 , pp. 590-598
    • Garcia-Fuentes, M.1    Alonso, M.J.2    Torres, D.3
  • 11
    • 18044366409 scopus 로고    scopus 로고
    • A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery
    • Garcia-Fuentes, M., Prego, C., Torres, D. and Alonso, M.J. (2005b) 'A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery', Eur. J. Pharm. Sci., Vol. 25, No. 1, pp.133-143.
    • (2005) Eur. J. Pharm. Sci , vol.25 , Issue.1 , pp. 133-143
    • Garcia-Fuentes, M.1    Prego, C.2    Torres, D.3    Alonso, M.J.4
  • 12
    • 0027908505 scopus 로고
    • Field flow fractionation: Analysis of macromolecular, colloidal, and particulate mater
    • Giddings, J.C. (1993) 'Field flow fractionation: Analysis of macromolecular, colloidal, and particulate mater', Science, Vol. 260, pp.1456-1465.
    • (1993) Science , vol.260 , pp. 1456-1465
    • Giddings, J.C.1
  • 13
    • 26244444984 scopus 로고    scopus 로고
    • Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system
    • Hu, F.Q., Jiang, S.P., Du, Y.Z., Yuan, H., Ye, Y.Q. and Zeng, S. (2005) 'Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system', Colloids Surf. B. Biointerfaces, Vol. 45, pp.167-173.
    • (2005) Colloids Surf. B. Biointerfaces , vol.45 , pp. 167-173
    • Hu, F.Q.1    Jiang, S.P.2    Du, Y.Z.3    Yuan, H.4    Ye, Y.Q.5    Zeng, S.6
  • 14
    • 33646081517 scopus 로고    scopus 로고
    • Preparation and characteristics of monostearin nanostructured lipid carriers
    • Hu, F.Q., Jiang, S.P., Du, Y.Z., Yuan, H., Ye, Y.Q. and Zeng, S. (2006) 'Preparation and characteristics of monostearin nanostructured lipid carriers', Int. J. Pharm., Vol. 314, No. 1, pp.83-89.
    • (2006) Int. J. Pharm , vol.314 , Issue.1 , pp. 83-89
    • Hu, F.Q.1    Jiang, S.P.2    Du, Y.Z.3    Yuan, H.4    Ye, Y.Q.5    Zeng, S.6
  • 15
    • 78651539810 scopus 로고    scopus 로고
    • Jain, S., Jain, S. and Jain, N.K. (2001) 'Transfersomes: A novel carrier for effective transdermal drug delivery', in Jain, N.K. (Ed.): Advances in Controlled and Novel Drug Delivery, CBS publishers and Distributors, pp.18, 426-451.
    • Jain, S., Jain, S. and Jain, N.K. (2001) 'Transfersomes: A novel carrier for effective transdermal drug delivery', in Jain, N.K. (Ed.): Advances in Controlled and Novel Drug Delivery, CBS publishers and Distributors, pp.18, 426-451.
  • 16
    • 77952582053 scopus 로고    scopus 로고
    • Ethosomes: A novel vesicular carrier for enhanced transdermal delivery of an anti-HIV agent
    • Jain, S., Umamaheshwari, R.B., Bhadra, D. and Jain, N.K. (2004) 'Ethosomes: A novel vesicular carrier for enhanced transdermal delivery of an anti-HIV agent', Ind. J. Pharm. Sci., Vol. 66, No. 1, pp.72-81.
    • (2004) Ind. J. Pharm. Sci , vol.66 , Issue.1 , pp. 72-81
    • Jain, S.1    Umamaheshwari, R.B.2    Bhadra, D.3    Jain, N.K.4
  • 17
    • 22144477226 scopus 로고    scopus 로고
    • Solid Lipid Nanoparticles bearing flurbiprofen for transdermal delivery
    • Jain, S.K., Chourasia, M.K., Masuriha, R., Soni, V., Jain, A., Jain, N.K. and Gupta, Y. (2005) 'Solid Lipid Nanoparticles bearing flurbiprofen for transdermal delivery', Drug Deliv., Vol. 12, No. 4, pp.207-215.
    • (2005) Drug Deliv , vol.12 , Issue.4 , pp. 207-215
    • Jain, S.K.1    Chourasia, M.K.2    Masuriha, R.3    Soni, V.4    Jain, A.5    Jain, N.K.6    Gupta, Y.7
  • 18
    • 33646566566 scopus 로고    scopus 로고
    • Sustained and targeted delivery of an anti-HIV agent using elastic liposomal formulation: Mechanism of action
    • Jain, S., Tiwary, A.K. and Jain, N.K. (2006) 'Sustained and targeted delivery of an anti-HIV agent using elastic liposomal formulation: mechanism of action', Current Drug Delivery, Vol. 3, No. 2, pp.157-166.
    • (2006) Current Drug Delivery , vol.3 , Issue.2 , pp. 157-166
    • Jain, S.1    Tiwary, A.K.2    Jain, N.K.3
  • 19
    • 0343618485 scopus 로고    scopus 로고
    • Characterization of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids
    • Jenning, V., Thunemann, A.F. and Gohla, S.H. (2000a) 'Characterization of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids', Int. J. Pharm., Vol. 199, No. 2, pp.167-177.
    • (2000) Int. J. Pharm , vol.199 , Issue.2 , pp. 167-177
    • Jenning, V.1    Thunemann, A.F.2    Gohla, S.H.3
  • 20
    • 17344391922 scopus 로고    scopus 로고
    • Vitamin A-loaded solid lipid nanoparticles for topical use: Drug release properties
    • Jenning, V., Schafer-Korting, M. and Gohla, S. (2000b) 'Vitamin A-loaded solid lipid nanoparticles for topical use: Drug release properties', J. Control. Release, Vol. 66, Nos. 2-3, pp.115-126.
    • (2000) J. Control. Release , vol.66 , Issue.2-3 , pp. 115-126
    • Jenning, V.1    Schafer-Korting, M.2    Gohla, S.3
  • 21
    • 0036153211 scopus 로고    scopus 로고
    • Medium scale production of solid lipid nanoparticles (SLN) by high pressure homogenization
    • Jenning, V., Lippacher, A. and Gohla, S.H. (2002) 'Medium scale production of solid lipid nanoparticles (SLN) by high pressure homogenization', J. Microencapsul., Vol. 19, No. 1, pp.1-10.
    • (2002) J. Microencapsul , vol.19 , Issue.1 , pp. 1-10
    • Jenning, V.1    Lippacher, A.2    Gohla, S.H.3
  • 22
    • 27144481028 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy
    • Jores, K., Haberland, A., Wartewig, S., Mader, K. and Mehnert, W. (2005) 'Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy', Pharm Res., Vol. 22, No. 11, pp.1887-1897.
    • (2005) Pharm Res , vol.22 , Issue.11 , pp. 1887-1897
    • Jores, K.1    Haberland, A.2    Wartewig, S.3    Mader, K.4    Mehnert, W.5
  • 23
    • 0042125467 scopus 로고    scopus 로고
    • Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: A nuclear magnetic resonance and electron spin resonance study
    • Jores, K., Mehnert, W. and Mader, K. (2003) 'Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: A nuclear magnetic resonance and electron spin resonance study', Pharm Res., Vol. 20, No. 8, pp.1274-1283.
    • (2003) Pharm Res , vol.20 , Issue.8 , pp. 1274-1283
    • Jores, K.1    Mehnert, W.2    Mader, K.3
  • 24
    • 1242338847 scopus 로고    scopus 로고
    • Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
    • Jores, K., Mehnert, W., Drechsler, M., Bunjes, H., Johann, C. and Mader, K. (2004) 'Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy', J. Control. Release, Vol. 95, No. 2, pp.217-227.
    • (2004) J. Control. Release , vol.95 , Issue.2 , pp. 217-227
    • Jores, K.1    Mehnert, W.2    Drechsler, M.3    Bunjes, H.4    Johann, C.5    Mader, K.6
  • 25
    • 33748498943 scopus 로고    scopus 로고
    • Formulation and evaluation of nanostructured lipid carrier (NLC)-based Gel of valdecoxib
    • Joshi, M. and Patravale, V. (2006) 'Formulation and evaluation of nanostructured lipid carrier (NLC)-based Gel of valdecoxib', Drug Dev. Ind. Pharm., Vol. 32, No. 8, pp.911-918.
    • (2006) Drug Dev. Ind. Pharm , vol.32 , Issue.8 , pp. 911-918
    • Joshi, M.1    Patravale, V.2
  • 26
    • 0031808981 scopus 로고    scopus 로고
    • Properties of a peptide containing DL - lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods
    • Kawashima, Y., Yamamoto, H., Takeuchi, H., Hino, T. and Niwa, T. (1998) 'Properties of a peptide containing DL - lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods', Eur. J. Pharm. Biopharm., Vol. 45, pp.41-48.
    • (1998) Eur. J. Pharm. Biopharm , vol.45 , pp. 41-48
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Hino, T.4    Niwa, T.5
  • 27
    • 0033982674 scopus 로고    scopus 로고
    • Influence of high pressure homogenisation equipment on nanodispersions characteristics
    • Liedtke, S., Wissing, S., Muller, R.H. and Mader, K. (2000) 'Influence of high pressure homogenisation equipment on nanodispersions characteristics', Int. J. Pharm., Vol. 196, pp.183-185.
    • (2000) Int. J. Pharm , vol.196 , pp. 183-185
    • Liedtke, S.1    Wissing, S.2    Muller, R.H.3    Mader, K.4
  • 28
    • 0342615073 scopus 로고    scopus 로고
    • Investigation on the viscoelastic properties of lipid based colloidal drug carriers
    • Lippacher, A., Muller, R.H. and Mader, K. (2000) 'Investigation on the viscoelastic properties of lipid based colloidal drug carriers', Int. J. Pharm., Vol. 196, pp.227-230.
    • (2000) Int. J. Pharm , vol.196 , pp. 227-230
    • Lippacher, A.1    Muller, R.H.2    Mader, K.3
  • 29
    • 0035910870 scopus 로고    scopus 로고
    • Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles
    • Lippacher, A., Muller, R.H. and Mader, K. (2001) 'Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles', Int. J. Pharm., Vol. 214, pp.9-12.
    • (2001) Int. J. Pharm , vol.214 , pp. 9-12
    • Lippacher, A.1    Muller, R.H.2    Mader, K.3
  • 30
    • 4644236384 scopus 로고    scopus 로고
    • Liquid and semisolid SLN dispersions for topical application: Rheological characterization
    • Lippacher, A., Muller, R.H. and Mader, K. (2004) 'Liquid and semisolid SLN dispersions for topical application: Rheological characterization', Eur. J. Pharm. Biopharm., Vol. 58, No. 3, pp.561-567.
    • (2004) Eur. J. Pharm. Biopharm , vol.58 , Issue.3 , pp. 561-567
    • Lippacher, A.1    Muller, R.H.2    Mader, K.3
  • 31
    • 33846912260 scopus 로고    scopus 로고
    • Nanostructured lipid carriers as vehicles for transdermal iontophoretic drug delivery, Engineering in Medicine and Biology Society
    • Liu, W., Yang, X.L., Zhu, Y.L., Chen, H.B. and Xu, H.B. (2005) 'Nanostructured lipid carriers as vehicles for transdermal iontophoretic drug delivery, Engineering in Medicine and Biology Society', IEEE-EMBS 27th Annual International Conference, pp.1236-1239.
    • (2005) IEEE-EMBS 27th Annual International Conference , pp. 1236-1239
    • Liu, W.1    Yang, X.L.2    Zhu, Y.L.3    Chen, H.B.4    Xu, H.B.5
  • 32
    • 0036205158 scopus 로고    scopus 로고
    • Nanoparticle technology for drug delivery across the blood brain barrier
    • Lockman, P.R., Mumper, R.J., Khan, M.A. and Allen, D.D. (2002) 'Nanoparticle technology for drug delivery across the blood brain barrier', Drug Dev. Ind Pharm., Vol. 28, No. 1, pp.1-12.
    • (2002) Drug Dev. Ind Pharm , vol.28 , Issue.1 , pp. 1-12
    • Lockman, P.R.1    Mumper, R.J.2    Khan, M.A.3    Allen, D.D.4
  • 33
    • 0033976172 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as drug carriers for topical glucocorticoids
    • Maia, C.S., Mehnert, W. and Schafer-Korting, M. (2000) 'Solid lipid nanoparticles as drug carriers for topical glucocorticoids', Int. J. Pharm., Vol. 196, No. 2, pp. 165-167.
    • (2000) Int. J. Pharm , vol.196 , Issue.2 , pp. 165-167
    • Maia, C.S.1    Mehnert, W.2    Schafer-Korting, M.3
  • 34
    • 24944496710 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduodenal administration
    • Manjunath, K. and Venkateswarlu, V. (2005) 'Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduodenal administration', J. Control. Release, Vol. 107, No. 2, pp.215-228.
    • (2005) J. Control. Release , vol.107 , Issue.2 , pp. 215-228
    • Manjunath, K.1    Venkateswarlu, V.2
  • 35
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • Mehnert, W. and Mader, K. (2001) 'Solid lipid nanoparticles: Production, characterization and applications', Adv. Drug Deliv. Rev., Vol. 47, No. 2, pp.165-196.
    • (2001) Adv. Drug Deliv. Rev , vol.47 , Issue.2 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 36
    • 0342904970 scopus 로고    scopus 로고
    • Drug release and release mechanism of prednisolone loaded solid lipid nanoparticles
    • Muhlen, A.Z. and Mehnert, W. (1998) 'Drug release and release mechanism of prednisolone loaded solid lipid nanoparticles',Pharmazie, Vol. 53, p.552.
    • (1998) Pharmazie , vol.53 , pp. 552
    • Muhlen, A.Z.1    Mehnert, W.2
  • 37
    • 78651530283 scopus 로고    scopus 로고
    • Muller, R.H. and Lucks, J.S, 1996, Arzneistofftrager aus festen Lipidteilchen, Feste Lipidnanospharen SLN, European Patent EP0605497, March
    • Muller, R.H. and Lucks, J.S. (1996) 'Arzneistofftrager aus festen Lipidteilchen, Feste Lipidnanospharen (SLN)', European Patent EP0605497, March.
  • 38
    • 6344258939 scopus 로고    scopus 로고
    • Drug delivery to the brain-realization by novel drug carriers
    • Müller, R.H. and Keck, C.M. (2004) 'Drug delivery to the brain-realization by novel drug carriers', J Nanosci. Nanotechnol. Vol. 4, No. 5, pp.471-483.
    • (2004) J Nanosci. Nanotechnol , vol.4 , Issue.5 , pp. 471-483
    • Müller, R.H.1    Keck, C.M.2
  • 39
    • 0001889786 scopus 로고    scopus 로고
    • The next generation after the liposomes: Solid lipid nanoparticles (SLN/Lipopearls) as dermal carrier in cosmetics
    • Vols
    • Muller, R.H. and Dingler, A. (1998) 'The next generation after the liposomes: Solid lipid nanoparticles (SLN/Lipopearls) as dermal carrier in cosmetics', Eur. Cosmet., Vols. 7-8, pp.19-26.
    • (1998) Eur. Cosmet , vol.7-8 , pp. 19-26
    • Muller, R.H.1    Dingler, A.2
  • 40
    • 0028954379 scopus 로고
    • Solid lipid nanoparticles (SLN) - an alternative colloidal carrier system for controlled drug delivery
    • Muller, R.H., Lucks, J.S., Schwarz, C., Zur Muhlen, A., Weyhers, H., Freitas, C. and Ruhl, D., (1995) 'Solid lipid nanoparticles (SLN) - an alternative colloidal carrier system for controlled drug delivery', Eur. J. Pharm. Biopham., Vol. 41, No. 1, pp.62-69.
    • (1995) Eur. J. Pharm. Biopham , vol.41 , Issue.1 , pp. 62-69
    • Muller, R.H.1    Lucks, J.S.2    Schwarz, C.3    Zur Muhlen, A.4    Weyhers, H.5    Freitas, C.6    Ruhl, D.7
  • 41
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art
    • Muller, R.H., Mader, K. and Gohla, S. (2000a) 'Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art', Eur. J. Pharm. Biopharm., Vol. 50, No. 1, pp. 161-177.
    • (2000) Eur. J. Pharm. Biopharm , vol.50 , Issue.1 , pp. 161-177
    • Muller, R.H.1    Mader, K.2    Gohla, S.3
  • 42
    • 78651522540 scopus 로고    scopus 로고
    • Muller, R.H, Mader, K, Lippacher, A. and Jenning, V, 2000b, Solid-liquid (semi-solid) lipid particles and method of producing highly concentrated lipid particle dispersion, German Patent Application, 199, No. 45, pp.203.2
    • Muller, R.H., Mader, K., Lippacher, A. and Jenning, V. (2000b) 'Solid-liquid (semi-solid) lipid particles and method of producing highly concentrated lipid particle dispersion', German Patent Application, Vol. 199, No. 45, pp.203.2.
  • 43
    • 0037151496 scopus 로고    scopus 로고
    • Nanostructured lipid matrices for improved microencapsulation of drugs
    • Muller, R.H., Radtke, M. and Wissing, S.A. (2002a) 'Nanostructured lipid matrices for improved microencapsulation of drugs', Int. J. Pharm. Vol. 242, Nos. 1-2, pp.121-128.
    • (2002) Int. J. Pharm , vol.242 , Issue.1-2 , pp. 121-128
    • Muller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 44
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • Muller, R.H., Radtke, M. and Wissing, S.A., (2002b) 'Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations', Adv. Drug Deliv. Rev., Vol. 54, Suppl. 1, pp.S131-155.
    • (2002) Adv. Drug Deliv. Rev , vol.54 , Issue.SUPPL. 1
    • Muller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 45
    • 33747736644 scopus 로고    scopus 로고
    • Evaluation of alternative strategies to optimize ketorolac transdermal delivery
    • Article 64, pp
    • Puglia, C., Filosa, R., Peduto, A., de Caprariis, P., Rizza, L., Bonina, F. and Blasi, P. (2006) 'Evaluation of alternative strategies to optimize ketorolac transdermal delivery', AAPS Pharm. SciTech., Vol. 7, No. 3, Article 64, pp.E1-E9.
    • (2006) AAPS Pharm. SciTech , vol.7 , Issue.3
    • Puglia, C.1    Filosa, R.2    Peduto, A.3    de Caprariis, P.4    Rizza, L.5    Bonina, F.6    Blasi, P.7
  • 46
    • 33646582966 scopus 로고    scopus 로고
    • Chemical stability of lipid excipients in SLN-production of test formulations, characterization and short-term stability
    • Radomska-Soukharev, A. and Muller, R.H. (2006) 'Chemical stability of lipid excipients in SLN-production of test formulations, characterization and short-term stability', Pharmazie, Vol. 61, No. 5, pp.425-430.
    • (2006) Pharmazie , vol.61 , Issue.5 , pp. 425-430
    • Radomska-Soukharev, A.1    Muller, R.H.2
  • 47
    • 0011625022 scopus 로고    scopus 로고
    • Nanostructured lipid drug carriers
    • Radtke, M. and Muller, R.H. (2001) 'Nanostructured lipid drug carriers', New Drugs, Vol. 2, pp.48-52.
    • (2001) New Drugs , vol.2 , pp. 48-52
    • Radtke, M.1    Muller, R.H.2
  • 48
    • 16344363233 scopus 로고    scopus 로고
    • Nanostructured lipid carriers: A novel generation of solid lipid drug carriers
    • Radtke, M., Souto, E.B. and Muller, R.H. (2005) 'Nanostructured lipid carriers: A novel generation of solid lipid drug carriers', Pharm. Tech. Eur., Vol. 17, No. 4, pp.45-50.
    • (2005) Pharm. Tech. Eur , vol.17 , Issue.4 , pp. 45-50
    • Radtke, M.1    Souto, E.B.2    Muller, R.H.3
  • 49
    • 20344403806 scopus 로고    scopus 로고
    • Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): In vitro and in vivo studies
    • Ricci, M., Puglia, C., Bonina, F., Di Giovanni, C., Giovagnoli, S. and Rossi, C. (2005) 'Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): In vitro and in vivo studies', J Pharm. Sci., Vol. 94, No. 5, pp. 1149-1159.
    • (2005) J Pharm. Sci , vol.94 , Issue.5 , pp. 1149-1159
    • Ricci, M.1    Puglia, C.2    Bonina, F.3    Di Giovanni, C.4    Giovagnoli, S.5    Rossi, C.6
  • 50
    • 33646106067 scopus 로고    scopus 로고
    • Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy
    • Saupe, A., Gordon, K.C. and Rades, T. (2006) 'Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy', Int. J. Pharm., Vol. 314, pp.56-62.
    • (2006) Int. J. Pharm , vol.314 , pp. 56-62
    • Saupe, A.1    Gordon, K.C.2    Rades, T.3
  • 51
    • 0029122546 scopus 로고
    • Sterilization and physical stability of drug -free and etomidate-loaded solid lipid nanoparticles
    • Schwarz, C., Freitas, C., Mehnert, W. and Muller, R.H. (1995) 'Sterilization and physical stability of drug -free and etomidate-loaded solid lipid nanoparticles', Proc. Int. Symp. Control. Rel. Bioact. Mater., Vol. 22, pp.766-767.
    • (1995) Proc. Int. Symp. Control. Rel. Bioact. Mater , vol.22 , pp. 766-767
    • Schwarz, C.1    Freitas, C.2    Mehnert, W.3    Muller, R.H.4
  • 52
    • 0028285718 scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization
    • Schwarz, C., Mehnert, W., Lucks, J.S. and Muller, R.H. (1994) 'Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization', J. Control. Release, Vol. 30, pp.83-96.
    • (1994) J. Control. Release , vol.30 , pp. 83-96
    • Schwarz, C.1    Mehnert, W.2    Lucks, J.S.3    Muller, R.H.4
  • 53
    • 0001469131 scopus 로고
    • Submicron sized parenteral carrier systems based on solid lipids
    • Siekmann, B. and Westesen, K. (1992) 'Submicron sized parenteral carrier systems based on solid lipids', Pharma. Pharmacol. Lett., Vol. 1, pp.123-126.
    • (1992) Pharma. Pharmacol. Lett , vol.1 , pp. 123-126
    • Siekmann, B.1    Westesen, K.2
  • 54
    • 0028548631 scopus 로고
    • Thermoanalysis of the recrystallization process of melt-homogenized glyceride nanoparticles
    • Siekmann, B. and Westesen, K. (1994) 'Thermoanalysis of the recrystallization process of melt-homogenized glyceride nanoparticles', Colloids Surf B. Biointerfaces, Vol. 3, No. 3, pp.159-175.
    • (1994) Colloids Surf B. Biointerfaces , vol.3 , Issue.3 , pp. 159-175
    • Siekmann, B.1    Westesen, K.2
  • 55
    • 0028839961 scopus 로고
    • Structure of nanoparticles prepared from oil - in - water emulsions
    • Siostrom, B., Kaplum, A., Talmon, B. and Cabane, C. (1995) 'Structure of nanoparticles prepared from oil - in - water emulsions', Pharm. Res. Vol. 12, No. 1, pp.39-48.
    • (1995) Pharm. Res , vol.12 , Issue.1 , pp. 39-48
    • Siostrom, B.1    Kaplum, A.2    Talmon, B.3    Cabane, C.4
  • 56
    • 31144438142 scopus 로고    scopus 로고
    • SLN and NLC for topical delivery of ketoconazole
    • Souto, E.B. and Muller, R.H. (2005) 'SLN and NLC for topical delivery of ketoconazole', J. Microencapsul., Vol. 22, No. 5, pp.501-510.
    • (2005) J. Microencapsul , vol.22 , Issue.5 , pp. 501-510
    • Souto, E.B.1    Muller, R.H.2
  • 57
    • 33646574622 scopus 로고    scopus 로고
    • The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents
    • Souto, E.B. and Muller, R. H. (2006) 'The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents', Pharmazie, Vol. 61, No. 5, pp.431-437.
    • (2006) Pharmazie , vol.61 , Issue.5 , pp. 431-437
    • Souto, E.B.1    Muller, R.H.2
  • 58
    • 25144431749 scopus 로고    scopus 로고
    • Rheology of nanostructured lipid carriers (NLC) suspended in a viscoelastic medium
    • Souto, E.B., Gohla, S.H. and Muller, R.H. (2005) 'Rheology of nanostructured lipid carriers (NLC) suspended in a viscoelastic medium', Pharmazie, Vol. 60, No. 9, pp.671-673.
    • (2005) Pharmazie , vol.60 , Issue.9 , pp. 671-673
    • Souto, E.B.1    Gohla, S.H.2    Muller, R.H.3
  • 59
    • 31144438142 scopus 로고    scopus 로고
    • SLN and NLC for topical delivery of ketoconazole
    • Souto, E.B. and Muller, R.H. (2005) 'SLN and NLC for topical delivery of ketoconazole', J. Microencapsul., Vol. 22, No. 5, pp.501-510.
    • (2005) J. Microencapsul , vol.22 , Issue.5 , pp. 501-510
    • Souto, E.B.1    Muller, R.H.2
  • 60
    • 10444233441 scopus 로고    scopus 로고
    • Comparative study between the viscoelastic behaviors of different lipid nanoparticles formulations
    • Souto, E.B., Wissing, S.A., Barbosa, C.M. and Muller, R.H. (2004a) 'Comparative study between the viscoelastic behaviors of different lipid nanoparticles formulations', J. Cosmet. Sci., Vol. 55, No. 5, pp.463-471.
    • (2004) J. Cosmet. Sci , vol.55 , Issue.5 , pp. 463-471
    • Souto, E.B.1    Wissing, S.A.2    Barbosa, C.M.3    Muller, R.H.4
  • 61
    • 2942676810 scopus 로고    scopus 로고
    • Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations
    • Souto, E.B., Wissing, S.A., Barbosa, C.M. and Muller, R.H. (2004b) 'Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations', Eur. J. Pharm. Biopharm. Vol. 58, No. 1, pp.83-90.
    • (2004) Eur. J. Pharm. Biopharm , vol.58 , Issue.1 , pp. 83-90
    • Souto, E.B.1    Wissing, S.A.2    Barbosa, C.M.3    Muller, R.H.4
  • 62
    • 34447305482 scopus 로고    scopus 로고
    • Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC) - Effects of formulation parameters on physicochemical stability
    • Teeranachaideekul, V., Muller, R.H. and Junyaprasert, V.B. (2007a) 'Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC) - Effects of formulation parameters on physicochemical stability', Int. J. Pharm., Vol. 340, pp. 198-206.
    • (2007) Int. J. Pharm , vol.340 , pp. 198-206
    • Teeranachaideekul, V.1    Muller, R.H.2    Junyaprasert, V.B.3
  • 63
    • 34250893864 scopus 로고    scopus 로고
    • Cetyl palmitate-based NLC for topical delivery of Coenzyme Q10-Development, physicochemical characterization and in vitro release studies
    • Teeranachaideekul, V., Souto, E.B., Junyaprasert, V.B., Rainer, H. and Muller, R.H. (2007b) 'Cetyl palmitate-based NLC for topical delivery of Coenzyme Q10-Development, physicochemical characterization and in vitro release studies', Eur. J. Pharm. Biopahrm., Vol. 67, pp. 141-148.
    • (2007) Eur. J. Pharm. Biopahrm , vol.67 , pp. 141-148
    • Teeranachaideekul, V.1    Souto, E.B.2    Junyaprasert, V.B.3    Rainer, H.4    Muller, R.H.5
  • 64
    • 0037433842 scopus 로고    scopus 로고
    • Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique
    • Trotta, M., Debernardi, F. and Caputo, O. (2003) 'Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique', Int. J. Pharm., Vol. 257, Nos. 1-2, pp. 153-160.
    • (2003) Int. J. Pharm , vol.257 , Issue.1-2 , pp. 153-160
    • Trotta, M.1    Debernardi, F.2    Caputo, O.3
  • 65
    • 33646540716 scopus 로고    scopus 로고
    • Preparation, characterization and physico-chemical properties of solid lipid nanoparticles and nanostructured lipid carriers (NLC): Their benefits as colloidal systems
    • Uner, M. (2006) 'Preparation, characterization and physico-chemical properties of solid lipid nanoparticles and nanostructured lipid carriers (NLC): Their benefits as colloidal systems', Pharmazie, Vol. 61, No. 5, pp.375-386.
    • (2006) Pharmazie , vol.61 , Issue.5 , pp. 375-386
    • Uner, M.1
  • 66
    • 23844466230 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate
    • Uner, M., Wissing, S.A., Yener, G. and Muller, R.H. (2005) 'Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate', Pharmazie, Vol. 60, No. 8, pp.577-582.
    • (2005) Pharmazie , vol.60 , Issue.8 , pp. 577-582
    • Uner, M.1    Wissing, S.A.2    Yener, G.3    Muller, R.H.4
  • 67
  • 68
    • 33748318061 scopus 로고    scopus 로고
    • Sun protection enhancement of titanium dioxide crystals by the use of carnauba wax nanoparticles: The synergistic interaction between organic and inorganic sunscreens at nanoscale
    • Villalobos-Hernández, J.R. and Müller-Goymann, CC. (2006) 'Sun protection enhancement of titanium dioxide crystals by the use of carnauba wax nanoparticles: The synergistic interaction between organic and inorganic sunscreens at nanoscale', Int. J. Pharm., Vol. 322, pp.161-170.
    • (2006) Int. J. Pharm , vol.322 , pp. 161-170
    • Villalobos-Hernández, J.R.1    Müller-Goymann, C.C.2
  • 69
    • 36248939564 scopus 로고    scopus 로고
    • In vitro erythernal UV-A protection factors of inorganic sunscreens distributed in aqueous media using carnauba wax-decyl oleate nanoparticles
    • Villalobos-Hernández, J.R. and Müller-Goymann, CC. (2007) 'In vitro erythernal UV-A protection factors of inorganic sunscreens distributed in aqueous media using carnauba wax-decyl oleate nanoparticles', Eur. J. Pharma. Biopharm., Vol. 65, pp.122-125.
    • (2007) Eur. J. Pharma. Biopharm , vol.65 , pp. 122-125
    • Villalobos-Hernández, J.R.1    Müller-Goymann, C.C.2
  • 70
    • 0036848464 scopus 로고    scopus 로고
    • Enhanced brain targeting by synthesis of 3′,5′-dioctanoyl-5-fluoro-2′-deoxyuridine and incorporation into solid lipid nanoparticles
    • Wang, J.X., Sun, X. and Zhang, Z.R. (2002) 'Enhanced brain targeting by synthesis of 3′,5′-dioctanoyl-5-fluoro-2′-deoxyuridine and incorporation into solid lipid nanoparticles', Eur. J. Pharm. Biopharm., Vol. 54, No. 3, pp.285 290.
    • (2002) Eur. J. Pharm. Biopharm , vol.54 , Issue.3 , pp. 285-290
    • Wang, J.X.1    Sun, X.2    Zhang, Z.R.3
  • 71
    • 0031006729 scopus 로고    scopus 로고
    • Investigation of the gel formation of phospholipids stabilized solid lipid nanoparticles
    • Westesen, K. and Siekmann, B. (1997) 'Investigation of the gel formation of phospholipids stabilized solid lipid nanoparticles', Int. J. Pharm., Vol. 151, pp.35-45.
    • (1997) Int. J. Pharm , vol.151 , pp. 35-45
    • Westesen, K.1    Siekmann, B.2
  • 72
    • 0034924386 scopus 로고    scopus 로고
    • A novel solvent system based on tocopherol acetate incorporated into solid lipid nanoparticles
    • Wissing, S.A. and Muller, R.H. (2001) 'A novel solvent system based on tocopherol acetate incorporated into solid lipid nanoparticles', Int. J. Cosmet. Sci., Vol. 23, pp.233-243.
    • (2001) Int. J. Cosmet. Sci , vol.23 , pp. 233-243
    • Wissing, S.A.1    Muller, R.H.2
  • 73
    • 0037124539 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as carrier for sunscreens: In vitro release and in vivo penetration
    • Wissing, S.A. and Muller, R.H. (2002) 'Solid lipid nanoparticles as carrier for sunscreens: In vitro release and in vivo penetration', J. Control. Release, Vol. 81, pp.225-233.
    • (2002) J. Control. Release , vol.81 , pp. 225-233
    • Wissing, S.A.1    Muller, R.H.2
  • 74
    • 0037453177 scopus 로고    scopus 로고
    • Cosmetic applications for solid lipid nanoparticles (SLN)
    • Wissing, S.A. and Muller, R.H. (2003) 'Cosmetic applications for solid lipid nanoparticles (SLN)' Int. J. Pharm., Vol. 254, pp.65-68.
    • (2003) Int. J. Pharm , vol.254 , pp. 65-68
    • Wissing, S.A.1    Muller, R.H.2
  • 75
    • 0032950389 scopus 로고    scopus 로고
    • Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain
    • Yang, S.C., Lu, L.F., Cai, Y., Zhu, J.B., Liang, B.W. and Yang, C.Z. (1999) 'Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain', J. Control. Release, Vol. 59, No. 3, pp.299-307.
    • (1999) J. Control. Release , vol.59 , Issue.3 , pp. 299-307
    • Yang, S.C.1    Lu, L.F.2    Cai, Y.3    Zhu, J.B.4    Liang, B.W.5    Yang, C.Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.