메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

New insights into the causes of human illness due to consumption of azaspiracid contaminated shellfish

Author keywords

[No Author keywords available]

Indexed keywords

AZASPIRACID; CARNITINE; GLUTARIC ACID; GLUTARIC ACID DERIVATIVE; GLUTARYLCARNITINE; MARINE TOXIN; SODIUM CHANNEL; SPIRO COMPOUND;

EID: 84937161110     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09818     Document Type: Article
Times cited : (31)

References (42)
  • 1
    • 0002893951 scopus 로고    scopus 로고
    • Winter toxicity of unknown aetiology in mussels
    • McMahon, T. & Silke, J. Winter toxicity of unknown aetiology in mussels. Harmful Algae News 2, 2-3 (1996
    • (1996) Harmful Algae News , vol.2 , pp. 2-3
    • McMahon, T.1    Silke, J.2
  • 3
    • 0033974774 scopus 로고    scopus 로고
    • Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland
    • Ito, E. et al. Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland. Toxicon 38, 917-930, doi:10.1016/s0041-0101 (99)00203-2 (2000).
    • (2000) Toxicon , vol.38 , pp. 917-930
    • Ito, E.1
  • 4
    • 0032582026 scopus 로고    scopus 로고
    • Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels, Mytilus edulis
    • Satake, M. et al. Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels, Mytilus edulis. J. Am. Chem. Soc. 120, 9967-9968, doi:Doi 10.1021/Ja981413r (1998)
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 9967-9968
    • Satake, M.1
  • 5
    • 4544298099 scopus 로고    scopus 로고
    • Structural revision and total synthesis of azaspiracid-1, part 1: Intelligence gathering and tentative proposal
    • Nicolaou, K. C. et al. Structural revision and total synthesis of azaspiracid-1, part 1: Intelligence gathering and tentative proposal. Angew. Chem.-Int. Edit. 43, 4312-4318, doi:10.1002/anie.200460695 (2004
    • (2004) Angew. Chem.-Int. Edit. , vol.43 , pp. 4312-4318
    • Nicolaou, K.C.1
  • 6
    • 84871972390 scopus 로고    scopus 로고
    • Molecular discrimination of taxa within the dinoflagellate genus Azadinium, the source of azaspiracid toxins
    • Toebe, K. et al. Molecular discrimination of taxa within the dinoflagellate genus Azadinium, the source of azaspiracid toxins. J Plankton Res 35, 225-230, doi:10.1093/plankt/fbs077 (2013
    • (2013) J Plankton Res , vol.35 , pp. 225-230
    • Toebe, K.1
  • 7
    • 84863488452 scopus 로고    scopus 로고
    • New azaspiracids in Amphidomataceae (Dinophyceae)
    • Krock, B. et al. New azaspiracids in Amphidomataceae (Dinophyceae). Toxicon 60, 830-839, doi:10.1016/j.toxicon.2012.05.007 (2012
    • (2012) Toxicon , vol.60 , pp. 830-839
    • Krock, B.1
  • 8
    • 84865187811 scopus 로고    scopus 로고
    • Blooms of Azadinium cf. spinosum Elbrachter et Tillmann (Dinophyceae) in northern shelf waters of ArgentinaSouthwestern Atlantic
    • Akselman, R. & Negri, R. M. Blooms of Azadinium cf. spinosum Elbrachter et Tillmann (Dinophyceae) in northern shelf waters of Argentina, Southwestern Atlantic. Harmful Algae 19, 30-38, doi:10.1016/j.hal.2012.05.004 (2012
    • (2012) Harmful Algae , vol.19 , pp. 30-38
    • Akselman, R.1    Negri, R.M.2
  • 10
    • 84870057726 scopus 로고    scopus 로고
    • First record of the genus Azadinium(Dinophyceae) from the Shetland Islands, including the description of Azadinium polongum sp nov
    • Tillmann, U., Soehner, S., Nezan, E. & Krock, B. First record of the genus Azadinium(Dinophyceae) from the Shetland Islands, including the description of Azadinium polongum sp nov. Harmful Algae 20, 142-155, doi:10.1016/j. hal.2012.10.001 (2012
    • (2012) Harmful Algae , vol.20 , pp. 142-155
    • Tillmann, U.1    Soehner, S.2    Nezan, E.3    Krock, B.4
  • 13
    • 46349102246 scopus 로고    scopus 로고
    • Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts
    • Twiner, M. J., Rehmann, N., Hess, P. & Doucette, G. J. Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts. Mar. Drugs 6, 39-72, doi:10.3390/md20080004 (2008
    • (2008) Mar. Drugs , vol.6 , pp. 39-72
    • Twiner, M.J.1    Rehmann, N.2    Hess, P.3    Doucette, G.J.4
  • 14
  • 15
    • 77951528520 scopus 로고    scopus 로고
    • Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons
    • Cao, Z., LePage, K. T., Frederick, M. O., Nicolaou, K. C. & Murray, T. F. Involvement of Caspase Activation in Azaspiracid-Induced Neurotoxicity in Neocortical Neurons. Toxicol. Sci. 114, 323-334, doi:10.1093/toxsci/kfp312 (2010
    • (2010) Toxicol. Sci. , vol.114 , pp. 323-334
    • Cao, Z.1    Lepage, K.T.2    Frederick, M.O.3    Nicolaou, K.C.4    Murray, T.F.5
  • 16
    • 84866402236 scopus 로고    scopus 로고
    • Marine algal toxin azaspiracid is an open-state blocker of herg potassium channels
    • Twiner, M. J. et al. Marine Algal Toxin Azaspiracid Is an Open-State Blocker of hERG Potassium Channels. Chem. Res. Toxicol. 25, 1975-1984, doi:10.1021/tx300283t (2012
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 1975-1984
    • Twiner, M.J.1
  • 17
    • 61449087418 scopus 로고    scopus 로고
    • Mussel-Associated azaspiracid intoxication in the united states
    • Klontz, K. C., Abraham, A., Plakas, S. M. & Dickey, R. W. Mussel-Associated Azaspiracid Intoxication in the United States. Ann. Intern. Med. 150, 361-361 (2009
    • (2009) Ann. Intern. Med. , vol.150 , pp. 361-361
    • Klontz, K.C.1    Abraham, A.2    Plakas, S.M.3    Dickey, R.W.4
  • 18
    • 84893933186 scopus 로고    scopus 로고
    • In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats
    • Ferreiro, S. F. et al. In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats. Arch. Toxicol. 88, 425-434, doi:10.1007/s00204-013-1115-4 (2014
    • (2014) Arch. Toxicol. , vol.88 , pp. 425-434
    • Ferreiro, S.F.1
  • 19
    • 53549095708 scopus 로고    scopus 로고
    • Azaspiracid substituent at C1 is relevant to in vitro toxicity
    • Vilarino, N. et al. Azaspiracid substituent at C1 is relevant to in vitro toxicity. Chem. Res. Toxicol. 21, 1823-1831, doi:10.1021/tx800165c (2008
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 1823-1831
    • Vilarino, N.1
  • 20
    • 75249087776 scopus 로고    scopus 로고
    • Cell volumedecrease as a link between azaspiracid-induced cytotoxicity and c-jun-n-terminal kinase activation in cultured neurons
    • Vale, C., Nicolaou, K. C., Frederick, M. O., Vieytes, M. R. & Botana, L. M. Cell VolumeDecrease as a Link between Azaspiracid-Induced Cytotoxicity and c-Jun-N-Terminal Kinase Activation in Cultured Neurons. Toxicol. Sci. 113, 158-168, doi:10.1093/toxsci/kfp246 (2010
    • (2010) Toxicol. Sci. , vol.113 , pp. 158-168
    • Vale, C.1    Nicolaou, K.C.2    Frederick, M.O.3    Vieytes, M.R.4    Botana, L.M.5
  • 21
    • 77953286406 scopus 로고    scopus 로고
    • Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations
    • Furey, A., O'Doherty, S., O'Callaghan, K., Lehane, M. & James, K. J. Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations. Toxicon 56, 173-190, doi:10.1016/j.toxicon.2009.09.009 (2010
    • (2010) Toxicon , vol.56 , pp. 173-190
    • Furey, A.1    O'Doherty, S.2    O'Callaghan, K.3    Lehane, M.4    James, K.J.5
  • 22
    • 0035401331 scopus 로고    scopus 로고
    • A cytotoxicity assay for the detection and differentiation of two families of shellfish toxins
    • Flanagan, A. F. et al. A cytotoxicity assay for the detection and differentiation of two families of shellfish toxins. Toxicon 39, 1021-1027, doi:10.1016/s0041-0101 (00)00241-5 (2001
    • (2001) Toxicon , vol.39 , pp. 1021-1027
    • Flanagan, A.F.1
  • 23
    • 84899411275 scopus 로고    scopus 로고
    • Epimers of azaspiracids: Isolation, structural elucidation, relative lc-ms response, and in vitro toxicity of 37-epi-azaspiracid-1
    • Kilcoyne, J. et al. Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, and in Vitro Toxicity of 37-epi-Azaspiracid-1. Chem. Res. Toxicol. 27, 587-600, doi:10.1021/tx400434b (2014
    • (2014) Chem. Res. Toxicol. , vol.27 , pp. 587-600
    • Kilcoyne, J.1
  • 24
    • 84864067373 scopus 로고    scopus 로고
    • Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route
    • Aune, T. et al. Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route. Toxicon 60, 895-906, doi:10.1016/j. toxicon.2012.06.007 (2012
    • (2012) Toxicon , vol.60 , pp. 895-906
    • Aune, T.1
  • 25
    • 84873388502 scopus 로고    scopus 로고
    • Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of alzheimer's disease
    • Graham, S. F. et al. Investigation of the Human Brain Metabolome to Identify Potential Markers for Early Diagnosis and Therapeutic Targets of Alzheimer's Disease. Anal. Chem. 85, 1803-1811, doi:10.1021/ac303163f (2013
    • (2013) Anal. Chem. , vol.85 , pp. 1803-1811
    • Graham, S.F.1
  • 26
    • 0032585736 scopus 로고    scopus 로고
    • Sensitivity and specificity of free and total glutaric acid and 3-hydroxyglutaric acid measurements by stable-isotope dilution assays for the diagnosis of glutaric aciduria type i
    • Baric, I. et al. Sensitivity and specificity of free and total glutaric acid and 3-hydroxyglutaric acid measurements by stable-isotope dilution assays for the diagnosis of glutaric aciduria type I. J. Inherit. Metab. Dis. 22, 867-881, doi:10.1023/a,1005683222187 (1999
    • (1999) J. Inherit. Metab. Dis. , vol.22 , pp. 867-881
    • Baric, I.1
  • 27
    • 3242706145 scopus 로고    scopus 로고
    • 3-hydroxyglutaric acid fails to affect the viability of primary neuronal rat cells
    • Freudenberg, F., Lukacs, Z. & Ullrich, K. 3-hydroxyglutaric acid fails to affect the viability of primary neuronal rat cells. Neurobiol. Dis. 16, 581-584, doi:10.1016/j. nbd.2004.05.001 (2004
    • (2004) Neurobiol. Dis. , vol.16 , pp. 581-584
    • Freudenberg, F.1    Lukacs, Z.2    Ullrich, K.3
  • 28
    • 33645881325 scopus 로고    scopus 로고
    • Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency
    • Sauer, S. W. et al. Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency. J. Neurochem. 97, 899-910, doi:10.1111/j.1471-4159.2006.03813.x (2006
    • (2006) J. Neurochem. , vol.97 , pp. 899-910
    • Sauer, S.W.1
  • 29
  • 30
    • 84865472344 scopus 로고    scopus 로고
    • Ion Channel Pharmacology under Flow: Automation Via Well-Plate Microfluidics
    • Spencer, C. I. et al. Ion Channel Pharmacology Under Flow: Automation Via Well-Plate Microfluidics. Assay Drug Dev. Technol. 10, 313-324, doi:10.1089/adt.2011.414 (2012
    • (2012) Assay Drug Dev. Technol. , vol.10 , pp. 313-324
    • Spencer, C.I.1
  • 31
    • 78650692977 scopus 로고    scopus 로고
    • Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type i
    • Sauer, S. W. et al. Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type I. Brain 134, 157-170, doi:10.1093/brain/awq269 (2011
    • (2011) Brain , vol.134 , pp. 157-170
    • Sauer, S.W.1
  • 32
    • 0037458492 scopus 로고    scopus 로고
    • Glutaric acid induces oxidative stress in brain of young rats
    • Marques, F. D. et al. Glutaric acid induces oxidative stress in brain of young rats. Brain Res. 964, 153-158, doi:10.1016/s0006-8993(02)04118-5 (2003
    • (2003) Brain Res. , vol.964 , pp. 153-158
    • Marques, F.D.1
  • 33
    • 36349019325 scopus 로고    scopus 로고
    • Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats
    • Rosa, R. B. et al. Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats. Life Sci. 81, 1668-1676, doi:10.1016/j.lfs.2007.09.021 (2007
    • (2007) Life Sci. , vol.81 , pp. 1668-1676
    • Rosa, R.B.1
  • 34
    • 33744802945 scopus 로고    scopus 로고
    • GMI ganglioside prevents seizures, Na1, K1-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole
    • Fighera, M. R. et al. GMI ganglioside prevents seizures, Na1, K1-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole. Neurobiol. Dis. 22, 611-623, doi:10.1016/j.nbd.2006.01.002 (2006
    • (2006) Neurobiol. Dis. , vol.22 , pp. 611-623
    • Fighera, M.R.1
  • 35
    • 0344701091 scopus 로고    scopus 로고
    • Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid
    • Lima, T. T. F. et al. Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid. Brain Res. 802, 55-60, doi:10.1016/s0006-8993(98)00563-0 (1998
    • (1998) Brain Res. , vol.802 , pp. 55-60
    • Lima, T.T.F.1
  • 36
    • 33646759551 scopus 로고    scopus 로고
    • Azaspiracid-1 inhibits bioelectrical activity of spinal cord neuronal networks
    • Kulagina, N. V. et al. Azaspiracid-1 inhibits bioelectrical activity of spinal cord neuronal networks. Toxicon 47, 766-773, doi:10.1016/j.toxicon.2006.02.011 (2006
    • (2006) Toxicon , vol.47 , pp. 766-773
    • Kulagina, N.V.1
  • 37
    • 0035158606 scopus 로고    scopus 로고
    • Low molecular weight dicarboxylic acids and glyoxylic acid: Seasonal and air mass characteristics
    • Rohrl, A. & Lammel, G. Low molecular weight dicarboxylic acids and glyoxylic acid: Seasonal and air mass characteristics. Environ. Sci. Technol. 35, 95-101, doi:10.1021/es0000448 (2001
    • (2001) Environ. Sci. Technol. , vol.35 , pp. 95-101
    • Rohrl, A.1    Lammel, G.2
  • 38
    • 0033512554 scopus 로고    scopus 로고
    • An analysis of rapid increases in condensation nuclei concentrations at a remote coastal site in western Ireland
    • Grenfell, J. L. et al. An analysis of rapid increases in condensation nuclei concentrations at a remote coastal site in western Ireland. J. Geophys. Res.-Atmospheres 104, 13771-13780, doi:10.1029/1999jd900096 (1999
    • (1999) J. Geophys. Res.-Atmospheres , vol.104 , pp. 13771-13780
    • Grenfell, J.L.1
  • 39
    • 84901759197 scopus 로고    scopus 로고
    • Glutaric acid-mediated apoptosis in primary striatal neurons
    • Tian, F. et al. Glutaric acid-mediated apoptosis in primary striatal neurons. BioMed research international 2014, 484731, doi:10.1155/2014/484731 (2014
    • (2014) BioMed Research International , vol.2014 , pp. 484731
    • Tian, F.1
  • 41
    • 83755180492 scopus 로고    scopus 로고
    • Metabolome in progression to Alzheimer's disease
    • Oresic, M. et al. Metabolome in progression to Alzheimer's disease. Transl. Psychiatr. 1, doi:10.1038/tp.2011.55 (2011
    • (2011) Transl. Psychiatr. , vol.1
    • Oresic, M.1
  • 42
    • 80055007441 scopus 로고    scopus 로고
    • 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular A beta and hyperphosphorylated tau in vitro
    • Alonso, E. et al. 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular A beta and hyperphosphorylated tau in vitro. Neurochem. Int. 59, 1056-1065, doi:10.1016/j.neuint.2011.08.013 (2011).
    • (2011) Neurochem. Int. , vol.59 , pp. 1056-1065
    • Alonso, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.