Ion channel pharmacology under flow: Automation via well-plate microfluidics

Assay and Drug Development Technologies

Volumn 10, Issue 4, 2012, Pages 313-324

  Spencer, C Ian ^a,c   Li, Nianzhen ^a   Chen, Qin ^a   Johnson, Juliette ^a   Nevill, Tanner ^a   Kammonen, Juha ^b   Ionescu Zanetti, Cristian ^a  

^a Fluxion Biosciences Inc   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ION CHANNEL; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA1; POTASSIUM CHANNEL HERG; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; UNCLASSIFIED DRUG;

ARTICLE; ELECTROPHYSIOLOGY; EXCITATORY JUNCTION POTENTIAL; MICROFLUIDICS; POTASSIUM CURRENT; VOLTAGE CLAMP;

ANIMALS; AUTOMATION; CHLORIDE CHANNELS; CHO CELLS; CRICETINAE; CRICETULUS; ETHER-A-GO-GO POTASSIUM CHANNELS; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; ION CHANNELS; KV1.2 POTASSIUM CHANNEL; MICROFLUIDIC ANALYTICAL TECHNIQUES; NAV1.7 VOLTAGE-GATED SODIUM CHANNEL; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RECEPTORS, CHOLINERGIC; RECEPTORS, GABA-A; REPRODUCIBILITY OF RESULTS; SODIUM CHANNEL BLOCKERS; SOLUTIONS;

EID: 84865472344     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2011.414     Document Type: Article

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