Azaspiracid-1 inhibits bioelectrical activity of spinal cord neuronal networks

Toxicon

Volumn 47, Issue 7, 2006, Pages 766-773

  Kulagina, Nadezhda V ^a   Twiner, Michael J ^b   Hess, Philipp ^c   McMahon, Terry ^c   Satake, Masayuki ^d   Yasumoto, Takeshi ^e   Ramsdell, John S ^b   Doucette, Gregory J ^b   Ma, Wu ^a   O'Shaughnessy, Thomas J ^a  

^a NAVAL RESEARCH LABORATORY   (United States)

^b CENTER FOR COASTAL ENVIRONMENTAL HEALTH AND BIOMOLECULAR RESEARCH   (United States)

^c MARINE INSTITUTE   (Ireland)

^d TOHOKU UNIVERSITY   (Japan)

^e JAPAN FOOD RESEARCH LABORATORIES   (Japan)

Author keywords

Action potential; Azaspiracid 1; Biosensor; Extracellular recording; Microelectrode array; Phycotoxin; Primary neuronal cultures; Voltage gated channels

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; AZASPIRACID; AZASPIRACID 1; BICUCULLINE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CALCIUM CURRENT; CONTROLLED STUDY; DRUG INHIBITION; EMBRYO; FRONTAL CORTEX; IC 50; MICROELECTRODE; MOUSE; NERVE CONDUCTION; NERVE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SODIUM CURRENT; SPIKE WAVE; SPINAL CORD NERVE CELL; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; MARINE TOXINS; MICE; NERVE NET; NEURONS; SODIUM; SPINAL CORD; SPIRO COMPOUNDS;

MOLLUSCA; MURINAE;

EID: 33646759551     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.02.011     Document Type: Article

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