Epimers of azaspiracids: Isolation, structural elucidation, relative LC-MS response, and in vitro toxicity of 37-epi-azaspiracid-1

Chemical Research in Toxicology

Volumn 27, Issue 4, 2014, Pages 587-600

  Kilcoyne, Jane ^a   McCarron, Pearse ^b   Twiner, Michael J ^c   Nulty, Ciara ^a   Crain, Sheila ^b   Quilliam, Michael A ^b   Rise, Frode ^d   Wilkins, Alistair L ^e,f   Miles, Christopher O ^d,e  

^a MARINE INSTITUTE   (Ireland)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c UNIVERSITY OF MICHIGAN DEARBORN   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e NORWEGIAN VETERINARY INSTITUTE   (Norway)

^f UNIVERSITY OF WAIKATO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

37 EPIAZASPIRACID 1; ACETONITRILE; AZASPIRACID; DYE; UNCLASSIFIED DRUG; MARINE TOXIN; SPIRO COMPOUND;

AQUEOUS SOLUTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONSUMER; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY ASSAY; DECARBOXYLATION; EPIMER; EPIMERIZATION; EXPERIMENTAL MODEL; FOOD CONTAMINATION; HALF LIFE TIME; IN VITRO STUDY; LEUKEMIA CELL LINE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUSSEL; PHYTOPLANKTON; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SEA FOOD; SHELLFISH; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; TIME; TOXICITY TESTING; TOXIN ANALYSIS; ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOLATION AND PURIFICATION; ISOMERISM; JURKAT CELL LINE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; IN VITRO TECHNIQUES; ISOMERISM; JURKAT CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MARINE TOXINS; MOLECULAR STRUCTURE; SHELLFISH; SPIRO COMPOUNDS; TANDEM MASS SPECTROMETRY;

EID: 84899411275     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400434b     Document Type: Article

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