Directed cardiomyogenesis of human pluripotent stem cells by modulating Wnt/β-catenin and BMP signalling with small molecules

Biochemical Journal

Volumn 469, Issue 2, 2015, Pages 235-241

  Aguilar, Jose S ^a   Begum, Aynun N ^a   Alvarez, Jonathan ^a   Zhang, Xiao Bing ^b   Hong, Yiling ^a,b   Hao, Jijun ^a  

^a WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BMP; Cardiomyogenesis; ESCs; IPSCs; Small molecules and dmh1; Wnt beta catenin

Indexed keywords

6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ALPHA TUBULIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; MYOSIN HEAVY CHAIN; NESTIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TROPONIN T; WNT PROTEIN; DMH1 COMPOUND; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINOLINE DERIVATIVE;

ARTICLE; CARDIAC STEM CELL; CARDIOMYOGENESIS; CELL DIFFERENTIATION; CELL LINEAGE; CELL RENEWAL; CONTROLLED STUDY; ECTODERM; ENDODERM; ENDOTHELIUM CELL; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MESODERM; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; METABOLISM; MUSCLE DEVELOPMENT; WNT SIGNALING PATHWAY;

BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; HUMANS; MUSCLE DEVELOPMENT; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; PYRAZOLES; PYRIDINES; PYRIMIDINES; QUINOLINES; WNT SIGNALING PATHWAY;

EID: 84937130313     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20150186     Document Type: Article

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