Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts

Journal of Biomedical Science

Volumn 22, Issue 1, 2015, Pages

  Lin, Chih Chung ^a,b   Pan, Chih Shuo ^b   Wang, Chen Yu ^b   Liu, Shiau Wen ^a,b   Hsiao, Li Der ^a,b   Yang, Chuen Mao ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Cardiac fibroblasts; EGFR transactivation; Monocytes adhesion; TNF ; VCAM 1

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C SRC; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; CSK TYROSINE-PROTEIN KINASE; EGFR PROTEIN, HUMAN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

ARTICLE; CARDITIS; CELL ACTIVATION; CELL ADHESION; CELL ADHESION ASSAY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; HEART FIBROBLAST; HEART INJURY; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; QUANTITATIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSACTIVATION ASSAY; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CARDIAC MUSCLE; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; TRANSCRIPTION INITIATION;

FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MYOCARDIUM; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PRIMARY CELL CULTURE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SRC-FAMILY KINASES; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84937039220     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/s12929-015-0165-8     Document Type: Article

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