Sirtuin-6 inhibits cardiac fibroblasts differentiation into myofibroblasts via inactivation of nuclear factor κB signaling

Translational Research

Volumn 165, Issue 3, 2015, Pages 374-386

  Tian, Kunming ^a   Liu, Zhiping ^a   Wang, Jiaojiao ^a   Xu, Suowen ^a,b   You, Tianhui ^a   Liu, Peiqing ^a,c  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

4 ,6 diamidino 2 phenylindol; AAC; Abbreviations; abdominal aortic constriction; Ang II; angiotensin II; cardiac fibroblast; CCK 8; Cell Counting Kit 8; CF; DAPI; ECM; EGFP; electrophoretic mobility shift assay; EMSA; enhanced green fluorescent protein; extracellular matrix; FCS; fetal calf serum; fibronectin; FN; GAPDH; glyceraldehyde 3 phosphate dehydrogenase; I B ; messenger RNA; mRNA; NAD; NC; negative control; NF B; nicotinamide adenine dinucleotide; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor B; PAI 1; PBS; PCR; PDTC; phosphate buffered saline; plasminogen activator inhibitor 1; polymerase chain reaction; pyrrolidine dithiocarbamate; SEM; siRNA; SIRT; SIRT6; sirtuin; Sirtuin 6; small interfering RNA; standard error of the mean; SMA; smooth muscle actin

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; ONCOPROTEIN; PYRROLIDINE DITHIOCARBAMATE; SIRTUIN 6; SMALL INTERFERING RNA; SIRTUIN; SIRTUIN 6, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE MARKER; DNA BINDING; EXTRACELLULAR MATRIX; FIBROBLAST; FOCAL ADHESION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; MALE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; FIBROSIS; GENE SILENCING; GENETIC TRANSCRIPTION; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; STENOSIS, OCCLUSION AND OBSTRUCTION;

ANGIOTENSIN II; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONSTRICTION, PATHOLOGIC; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; FIBROSIS; FOCAL ADHESIONS; GENE SILENCING; MALE; MYOCARDIUM; MYOFIBROBLASTS; NF-KAPPA B; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIRTUINS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84924528336     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2014.08.008     Document Type: Article

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