Robust expansion of human pluripotent stem cells: Integration of bioprocess design with transcriptomic and metabolomic characterization

Stem Cells Translational Medicine

Volumn 4, Issue 7, 2015, Pages 731-742

  Silva, Marta M ^a,b   Rodrigues, Ana F ^a,b   Correia, Cláudia ^a,b   Sousa, Marcos F Q ^a,b   Brito, Catarina ^a,b   Coroadinha, Ana S ^a,b   Serra, Margarida ^a,b   Alves, Paula M ^a,b  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

Human pluripotent stem cells; Metabolic profiling; Stirred tank bioreactors; Transcriptional profiling; Xeno free microcarriers

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE 6 PHOSPHATE ISOMERASE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; HEPATOCYTE NUCLEAR FACTOR 3BETA; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRA1 60 PROTEIN; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG; UVOMORULIN;

ANAEROBIC GLYCOLYSIS; ARTICLE; BIOPROCESS; CARBON METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; METABOLOMICS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLURIPOTENT STEM CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS; TISSUE ENGINEERING; TRANSCRIPTOMICS; UPREGULATION;

EID: 84936999040     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0270     Document Type: Article

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