-
1
-
-
66149093072
-
The pathology of chronic obstructive pulmonary disease
-
Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol. 2009;4: 435-459.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 435-459
-
-
Hogg, J.C.1
Timens, W.2
-
2
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3: e442.
-
(2006)
PLoS Med
, vol.3
, pp. e442
-
-
Mathers, C.D.1
Loncar, D.2
-
3
-
-
35148893108
-
Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should)
-
Agusti A. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should). Proc Am Thorac Soc. 2007;4: 522-525.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 522-525
-
-
Agusti, A.1
-
4
-
-
37349010640
-
Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations
-
Wouters EF, Groenewegen KH, Dentener MA, Vernooy JH. Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations. Proc Am Thorac Soc. 2007;4(8): 626-634.
-
(2007)
Proc Am Thorac Soc
, vol.4
, Issue.8
, pp. 626-634
-
-
Wouters, E.F.1
Groenewegen, K.H.2
Dentener, M.A.3
Vernooy, J.H.4
-
5
-
-
34247564631
-
Increased proportion of Fas positive CD8+ cells in peripheral blood of patients with COPD
-
Domagała-Kulawik J, Hoser G, Dabrowska M, Chazan R. Increased proportion of Fas positive CD8+ cells in peripheral blood of patients with COPD. Respir Med. 2007;101(6): 1338-1343.
-
(2007)
Respir Med
, vol.101
, Issue.6
, pp. 1338-1343
-
-
Domagała-Kulawik, J.1
Hoser, G.2
Dabrowska, M.3
Chazan, R.4
-
6
-
-
60249085440
-
Role of T-lymphocytes and pro-inflammatory mediators in the pathogenesis of chronic obstructive pulmonary disease
-
Gadgil A, Duncan SR. Role of T-lymphocytes and pro-inflammatory mediators in the pathogenesis of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2008;3: 531-541.
-
(2008)
Int J Chron Obstruct Pulmon Dis
, vol.3
, pp. 531-541
-
-
Gadgil, A.1
Duncan, S.R.2
-
7
-
-
35148862090
-
The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research
-
Curtis JL, Freeman CM, Hogg JC. The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research. Proc Am Thorac Soc. 2007;4: 512-521.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 512-521
-
-
Curtis, J.L.1
Freeman, C.M.2
Hogg, J.C.3
-
9
-
-
85081880795
-
-
Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. NHLBI/WHO workshop report. NIH Publication
-
Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease. NHLBI/WHO workshop report. NIH Publication no. 2701:1-100.
-
, vol.2701
, pp. 1-100
-
-
-
10
-
-
85081878388
-
Bethesda, MD: National Heart, Lung and Blood Institute, April 2001
-
Last update 2008. Available at: (accessed 12 March 2009). 2.
-
Rabe KF, Hurd S, Anzueto A, etal. Bethesda, MD: National Heart, Lung and Blood Institute, April 2001. Last update 2008. Available at: http://www.goldcopd.com (accessed 12 March 2009). 2.
-
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
-
11
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, etal. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med. 2004;350: 2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
12
-
-
14444279391
-
Severity of airflow limitation is associated with severity of airway inflammation in smokers
-
Di Stefano A, Capelli A, Lusuardi M, Balbo P, Vecchio C, Maestrelli P, Mapp CE, Fabbri LM, Donner CF, Saetta M. Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med. 1998;158: 1277-1285.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1277-1285
-
-
Di Stefano, A.1
Capelli, A.2
Lusuardi, M.3
Balbo, P.4
Vecchio, C.5
Maestrelli, P.6
Mapp, C.E.7
Fabbri, L.M.8
Donner, C.F.9
Saetta, M.10
-
13
-
-
66649127821
-
Immunologic aspects of chronic obstructive pulmonary disease
-
Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med. 2009;360: 2445-2454.
-
(2009)
N Engl J Med
, vol.360
, pp. 2445-2454
-
-
Cosio, M.G.1
Saetta, M.2
Agusti, A.3
-
14
-
-
33645321836
-
Cigarette smoke-induced emphysema: a role for the B cell?
-
van der Strate BW, Postma DS, Brandsma CA, Melgert BN, Luinge MA, Geerlings M, Hylkema MN, van den Berg A, Timens W, Kerstjens HA. Cigarette smoke-induced emphysema: a role for the B cell? Am J Respir Crit Care Med. 2006;173: 751-758.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 751-758
-
-
van der Strate, B.W.1
Postma, D.S.2
Brandsma, C.A.3
Melgert, B.N.4
Luinge, M.A.5
Geerlings, M.6
Hylkema, M.N.7
van den Berg, A.8
Timens, W.9
Kerstjens, H.A.10
-
15
-
-
34249652351
-
Anti-elastin autoimmunity in tobacco smoking-induced emphysema
-
Lee SH, Goswami S, Grudo A, etal. Anti-elastin autoimmunity in tobacco smoking-induced emphysema. Nat Med. 2007;13: 567-569.
-
(2007)
Nat Med
, vol.13
, pp. 567-569
-
-
Lee, S.H.1
Goswami, S.2
Grudo, A.3
-
16
-
-
3543140733
-
Autoimmunity, T-cells and STAT-4 in the pathogenesis of chronic obstructive pulmonary disease
-
Cosio MG. Autoimmunity, T-cells and STAT-4 in the pathogenesis of chronic obstructive pulmonary disease. Eur Respir J. 2004;24: 3-5.
-
(2004)
Eur Respir J
, vol.24
, pp. 3-5
-
-
Cosio, M.G.1
-
17
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. N Engl J Med. 2009;361: 888-898.
-
(2009)
N Engl J Med
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
-
18
-
-
77949653161
-
Development, regulation and functional capacities of Th17 cells
-
Hirota K, Martin B, Veldhoen M. Development, regulation and functional capacities of Th17 cells. Semin Immunopathol. 2010;32: 3-16.
-
(2010)
Semin Immunopathol
, vol.32
, pp. 3-16
-
-
Hirota, K.1
Martin, B.2
Veldhoen, M.3
-
19
-
-
80052961881
-
Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease
-
Vargas-Rojas MI, Ramírez-Venegas A, Limón-Camacho L, Ochoa L, Hernández-Zenteno R, Sansores RH. Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease. Respir Med. 2011;105: 1648-1654.
-
(2011)
Respir Med
, vol.105
, pp. 1648-1654
-
-
Vargas-Rojas, M.I.1
Ramírez-Venegas, A.2
Limón-Camacho, L.3
Ochoa, L.4
Hernández-Zenteno, R.5
Sansores, R.H.6
-
20
-
-
67650653218
-
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients
-
Di Stefano A, Caramori G, Gnemmi I, etal. T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol. 2009;157: 316-324.
-
(2009)
Clin Exp Immunol
, vol.157
, pp. 316-324
-
-
Di Stefano, A.1
Caramori, G.2
Gnemmi, I.3
-
21
-
-
78349269946
-
Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD
-
Doe C, Bafadhel M, Siddiqui S, etal. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest. 2010;138: 1140-1147.
-
(2010)
Chest
, vol.138
, pp. 1140-1147
-
-
Doe, C.1
Bafadhel, M.2
Siddiqui, S.3
-
23
-
-
78650041389
-
CD4+/CD25+ cells in systemic inflammation in COPD
-
Domagała-Kulawik J, Hoser G, Dabrowska M, Safianowska A, Chazan R. CD4+/CD25+ cells in systemic inflammation in COPD. Scand J Immunol. 2011;73: 59-65.
-
(2011)
Scand J Immunol
, vol.73
, pp. 59-65
-
-
Domagała-Kulawik, J.1
Hoser, G.2
Dabrowska, M.3
Safianowska, A.4
Chazan, R.5
-
24
-
-
84870410032
-
Imbalance of Th17/Treg cells in mice with chronic cigarette smoke exposure
-
Wang H, Peng W, Weng Y, Ying H, Li H, Xia D, Yu W. Imbalance of Th17/Treg cells in mice with chronic cigarette smoke exposure. Int Immunopharmacol. 2012;14: 504-512.
-
(2012)
Int Immunopharmacol
, vol.14
, pp. 504-512
-
-
Wang, H.1
Peng, W.2
Weng, Y.3
Ying, H.4
Li, H.5
Xia, D.6
Yu, W.7
-
26
-
-
34447556991
-
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
-
Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev. 2007;87: 1047-1082.
-
(2007)
Physiol Rev
, vol.87
, pp. 1047-1082
-
-
Yoshida, T.1
Tuder, R.M.2
-
28
-
-
39449126502
-
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
-
Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol. 2008;9: 239-244.
-
(2008)
Nat Immunol
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
-
29
-
-
58849142042
-
Decreased FOXP3 expression in small airways of smokers with COPD
-
Isajevs S, Taivans I, Strazda G, Kopeika U, Bukovskis M, Gordjusina V, Kratovska A. Decreased FOXP3 expression in small airways of smokers with COPD. Eur Respir J. 2009;33: 61-67.
-
(2009)
Eur Respir J
, vol.33
, pp. 61-67
-
-
Isajevs, S.1
Taivans, I.2
Strazda, G.3
Kopeika, U.4
Bukovskis, M.5
Gordjusina, V.6
Kratovska, A.7
-
31
-
-
42949090409
-
Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4+CD25+ regulatory T-lymphocyte response to tobacco smoking
-
Barceló B, Pons J, Ferrer JM, Sauleda J, Fuster A, Agustí AG. Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4+CD25+ regulatory T-lymphocyte response to tobacco smoking. Eur Respir J. 2008;31: 555-562.
-
(2008)
Eur Respir J
, vol.31
, pp. 555-562
-
-
Barceló, B.1
Pons, J.2
Ferrer, J.M.3
Sauleda, J.4
Fuster, A.5
Agustí, A.G.6
-
32
-
-
84887501001
-
Imbalance between subpopulations of regulatory T cells in COPD
-
Hou J, Sun Y, Hao Y, Zhuo J, Liu X, Bai P, Han J, Zheng X, Zeng H. Imbalance between subpopulations of regulatory T cells in COPD. Thorax. 2013;68: 1131-1139.
-
(2013)
Thorax
, vol.68
, pp. 1131-1139
-
-
Hou, J.1
Sun, Y.2
Hao, Y.3
Zhuo, J.4
Liu, X.5
Bai, P.6
Han, J.7
Zheng, X.8
Zeng, H.9
-
33
-
-
84859416933
-
Regulatory T cells: mechanisms of differentiation and function
-
Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol. 2012;30: 531-564.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
34
-
-
85081879205
-
-
Tobacco Smoking. European Lung White Book. The European Respiratory Society
-
Tobacco Smoking. European Lung White Book. The European Respiratory Society, 2004: 108-124.
-
(2004)
, pp. 108-124
-
-
-
35
-
-
54049158837
-
Airway infiltration of CD4+ CCR6+ Th17 type cells associated with chronic cigarette smoke induced airspace enlargement
-
Harrison OJ, Foley J, Bolognese BJ, Long E III, Podolin PL, Walsh PT. Airway infiltration of CD4+ CCR6+ Th17 type cells associated with chronic cigarette smoke induced airspace enlargement. Immunol Lett. 2008;121: 13-21.
-
(2008)
Immunol Lett
, vol.121
, pp. 13-21
-
-
Harrison, O.J.1
Foley, J.2
Bolognese, B.J.3
Long, E.4
Podolin, P.L.5
Walsh, P.T.6
-
36
-
-
79952337776
-
Chronic bronchitis and emphysema
-
In: Mason RJ, Martin TR, King TE Jr, Schraufnagel DE, Murray JF, Jay A, editors., Philadelphia, PA, Saunders
-
Shapiro SD, Reilly JJJ, Rennard SI. Chronic bronchitis and emphysema. In: Mason RJ, Martin TR, King TE Jr, Schraufnagel DE, Murray JF, Jay A, editors. Nadel Textbood of Respiratory Medicine, Vol. I. Philadelphia, PA, Saunders, 2010: 919-967.
-
(2010)
Nadel Textbood of Respiratory Medicine
, vol.1
, pp. 919-967
-
-
Shapiro, S.D.1
Reilly, J.J.J.2
Rennard, S.I.3
-
37
-
-
69149102202
-
Chronic obstructive pulmonary disease in non-smokers
-
Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet. 2009;374: 733-743.
-
(2009)
Lancet
, vol.374
, pp. 733-743
-
-
Salvi, S.S.1
Barnes, P.J.2
-
38
-
-
77956993930
-
Association of severity of COPD with IgE and interleukin-1 beta
-
Singh B, Arora S, Khanna V. Association of severity of COPD with IgE and interleukin-1 beta. Monaldi Arch Chest Dis. 2010;73: 86-87.
-
(2010)
Monaldi Arch Chest Dis
, vol.73
, pp. 86-87
-
-
Singh, B.1
Arora, S.2
Khanna, V.3
-
39
-
-
84863617821
-
IL-21 promotes lupus-like disease in chronic graft-vs-host disease through both CD4 T cell- and B cell-intrinsic mechanisms
-
Nguyen V, Luzina I, Rus H, Tegla C, Chen C, Rus V. IL-21 promotes lupus-like disease in chronic graft-vs-host disease through both CD4 T cell- and B cell-intrinsic mechanisms. J Immunol. 2012;189: 1081-1093.
-
(2012)
J Immunol
, vol.189
, pp. 1081-1093
-
-
Nguyen, V.1
Luzina, I.2
Rus, H.3
Tegla, C.4
Chen, C.5
Rus, V.6
-
40
-
-
34547204946
-
Essential auto-crine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, Yang XO, Martinez G, etal. Essential auto-crine regulation by IL-21 in the generation of inflammatory T cells. Nature. 2007;448: 480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
-
41
-
-
83355169701
-
Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis
-
Rico de Souza A, Zago M, Pollock SJ, Sime PJ, Phipps RP, Baglole CJ. Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis. J Biol Chem. 2011;286: 43214-43228.
-
(2011)
J Biol Chem
, vol.286
, pp. 43214-43228
-
-
Rico de Souza, A.1
Zago, M.2
Pollock, S.J.3
Sime, P.J.4
Phipps, R.P.5
Baglole, C.J.6
-
42
-
-
77956469491
-
Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells
-
Ramirez JM, Brembilla NC, Sorg O, Chicheportiche R, Matthes T, Dayer JM, Saurat JH, Roosnek E, Chizzolini C. Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. Eur J Immunol. 2010;40: 2450-2459.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2450-2459
-
-
Ramirez, J.M.1
Brembilla, N.C.2
Sorg, O.3
Chicheportiche, R.4
Matthes, T.5
Dayer, J.M.6
Saurat, J.H.7
Roosnek, E.8
Chizzolini, C.9
-
43
-
-
84880720706
-
Expression of interleukin (IL)-10, IL-17A and IL-22 in serum and sputum of stable chronic obstructive pulmonary disease patients
-
Zhang L, Cheng Z, Liu W, Wu K. Expression of interleukin (IL)-10, IL-17A and IL-22 in serum and sputum of stable chronic obstructive pulmonary disease patients. COPD. 2013;10: 459-465.
-
(2013)
COPD
, vol.10
, pp. 459-465
-
-
Zhang, L.1
Cheng, Z.2
Liu, W.3
Wu, K.4
-
44
-
-
84866742560
-
TGF-β signalling in context
-
Massagué J. TGF-β signalling in context. Mol Cell Biol. 2012;13: 616-630.
-
(2012)
Mol Cell Biol
, vol.13
, pp. 616-630
-
-
Massagué, J.1
-
45
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol. 2008;9: 641-649.
-
(2008)
Nat Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
46
-
-
44049102724
-
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses
-
Volpe E, Servant N, Zollinger R, Bogiatzi SI, Hupé P, Barillot E, Soumelis V. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol. 2008;9: 650-657.
-
(2008)
Nat Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
Servant, N.2
Zollinger, R.3
Bogiatzi, S.I.4
Hupé, P.5
Barillot, E.6
Soumelis, V.7
-
47
-
-
70349123761
-
New paradigms in the pathogenesis of chronic obstructive pulmonary disease II
-
Sethi S, Mallia P, Johnston SL. New paradigms in the pathogenesis of chronic obstructive pulmonary disease II. Proc Am Thorac Soc. 2009;6: 532-534.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 532-534
-
-
Sethi, S.1
Mallia, P.2
Johnston, S.L.3
-
48
-
-
84859424158
-
Chronic obstructive pulmonary disease
-
Decramer M, Janssens W, Miravitlles M. Chronic obstructive pulmonary disease. Lancet. 2012;379: 1341-1351.
-
(2012)
Lancet
, vol.379
, pp. 1341-1351
-
-
Decramer, M.1
Janssens, W.2
Miravitlles, M.3
|