Imbalance of Th17/Treg cells in mice with chronic cigarette smoke exposure

International Immunopharmacology

Volumn 14, Issue 4, 2012, Pages 504-512

  Wang, Huaying ^a   Peng, Weidong ^a   Weng, Yuesong ^b   Ying, Huajuan ^a   Li, Hequan ^c   Xia, Dajing ^d   Yu, Wanjun ^a  

^a NINGBO UNIVERSITY   (China)

^b NINGBO FIRST HOSPITAL   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cigarette exposure; COPD; Immune imbalance; Mouse model; Regulatory T cells; Th17 cells

Indexed keywords

CIGARETTE SMOKE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; MESSENGER RNA; RETINOIC ACID RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; SMOKING; TH17 CELL;

ANIMALS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; LUNG; MALE; MICE; MICE, INBRED C57BL; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TIME FACTORS; TOBACCO SMOKE POLLUTION;

EID: 84870410032     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.09.011     Document Type: Article

References (46)

1. J.C. Hogg, and W. Timens The pathology of chronic obstructive pulmonary disease Annu Rev Pathol 4 2009 435 459
2. C.D. Mathers, and D. Loncar Projections of global mortality and burden of disease from 2002 to 2030 PLoS Med 3 2006 e442
3. R.A. Pauwels, and K.F. Rabe Burden and clinical features of chronic obstructive pulmonary disease (COPD) Lancet 364 2004 613 620
4. M.G. Cosio, M. Saetta, and A. Agusti Immunologic aspects of chronic obstructive pulmonary disease N Engl J Med 360 2009 2445 2454
5. M.T. Borchers, S.C. Wesselkamper, V. Curull, A. Ramirez-Sarmiento, A. Sánchez-Font, and J. Garcia-Aymerich Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease J Clin Invest 119 2009 636 649
6. G.T. Motz, B.L. Eppert, G. Sun, S.C. Wesselkamper, M.J. Linke, and R. Deka Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema J Immunol 181 2008 8036 8043
7. B.W. van der Strate, D.S. Postma, C.A. Brandsma, B.N. Melgert, M.A. Luinge, and M. Geerlings Cigarette smoke-induced emphysema: a role for the B cell? Am J Respir Crit Care Med 173 2006 751 758
8. S.H. Lee, S. Goswami, A. Grudo, L.Z. Song, V. Bandi, and S. Goodnight-White Anti-elastin autoimmunity in tobacco smoking-induced emphysema Nat Med 13 2007 567 569
9. K. Hirota, B. Martin, and M. Veldhoen Development, regulation and functional capacities of Th17 cells Semin Immunopathol 32 2010 3 16
10. P. Miossec, T. Korn, and V.K. Kuchroo Interleukin-17 and type 17 helper T cells N Engl J Med 361 2009 888 898
11. K. Nistala, H. Moncrieffe, K.R. Newton, H. Varsani, P. Hunter, and L.R. Wedderburn Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers Arthritis Rheum 58 2008 875 887
12. J.S. Tzartos, M.A. Friese, M.J. Craner, J. Palace, J. Newcombe, and M.M. Esiri Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis Am J Pathol 172 2008 146 155
13. K. Hirota, H. Yoshitomi, M. Hashimoto, S. Maeda, S. Teradaira, and N. Sugimoto Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model J Exp Med 204 2007 2803 2812
14. Y.K. Lee, R. Mukasa, R.D. Hatton, and C.T. Weaver Developmental plasticity of Th17 and Treg cells Curr Opin Immunol 21 2009 274 280
15. C.M. Costantino, C.M. Baecher-Allan, and D.A. Hafler Human regulatory T cells and autoimmunity Eur J Immunol 38 2008 921 924
16. K.R. Bracke, A.I. D'hulst, T. Maes, K.B. Moerloose, I.K. Demedts, and S. Lebecque Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice J Immunol 177 2006 4350 4359
17. G.J. Patskan, K.F. Podraza, K. Meurrens, C.R. Coggins, B. Friedrichs, and B. Gerstenberg Toxicological comparisons of three styles of a commercial U.S. cigarette Marlboro with the 1R4F reference cigarette Inhal Toxicol 20 2008 695 721
18. J.C. Hogg, F. Chu, S. Utokaparch, R. Woods, W.M. Elliott, and L. Buzatu The nature of small-airway obstruction in chronic obstructive pulmonary disease N Engl J Med 350 2004 2645 2653
19. K. Górska, M. Maskey-Warzechowska, and R. Krenke Airway inflammation in chronic obstructive pulmonary disease Curr Opin Pulm Med 16 2010 89 96
20. A. Tamimi, D. Serdarevic, and N.A. Hanania The effects of cigarette smoke on airway inflammation in asthma and COPD: therapeutic implications Respir Med 106 2012 319 328
21. K. Amin The role of mast cells in allergic inflammation Respir Med 106 2012 9 14
22. A. Gadgil, and S.R. Duncan Role of T-lymphocytes and pro-inflammatory mediators in the pathogenesis of chronic obstructive pulmonary disease Int J Chron Obstruct Pulmon Dis 3 2008 531 541
23. J. Vila, J.D. Isaacs, and A.E. Anderson Regulatory T cells and autoimmunity Curr Opin Hematol 16 2009 274 279
24. S. Isajevs, I. Taivans, G. Strazda, U. Kopeika, M. Bukovskis, and V. Gordjusina Decreased FOXP3 expression in small airways of smokers with COPD Eur Respir J 33 2009 61 67
25. L.J. Smyth, C. Starkey, J. Vestbo, and D. Singh CD4-regulatory T-cells in COPD patients Chest 132 2007 156 163
26. S.H. Lee, S. Goswami, A. Grudo, L.Z. Song, V. Bandi, and S. Goodnight-White Antielastin autoimmunity in tobacco smoking induced emphysema Nat Med 13 2007 567 569
27. B. Barceló, J. Pons, J.M. Ferrer, J. Sauleda, A. Fuster, and A.G. Agustí Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4+CD25 + regulatory T-lymphocyte response to tobacco smoking Eur Respir J 31 2008 555 562
28. P.J. Barnes The cytokine network in chronic obstructive pulmonary disease Am J Respir Cell Mol Biol 41 2009 631 638
29. S. Takanashi, Y. Hasegawa, Y. Kanehira, K. Yamamoto, K. Fujimoto, and K. Satoh Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers Eur Respir J 14 1999 309 314
30. T.L. Hackett, R. Holloway, S.T. Holgate, and J.A. Warner Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study Respir Res 9 2008 47
31. M.I. Vargas-Rojas, A. Ramírez-Venegas, L. Limón-Camacho, L. Ochoa, R. Hernández-Zenteno, and R.H. Sansores Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease Respir Med 105 2011 1648 1654
32. E. Bettelli, M. Oukka, and V.K. Kuchroo T(H)-17 cells in the circle of immunity and autoimmunity Nat Immunol 8 2007 345 350
33. A. Di Stefano, G. Caramori, I. Gnemmi, M. Contoli, C. Vicari, and A. Capelli T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients Clin Exp Immunol 157 2009 316 324
34. K. Chen, D.A. Pociask, J.P. McAleer, Y.R. Chan, J.F. Alcorn, and J.L. Kreindler IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke PLoS One 6 2011 e20333
35. O.J. Harrison, J. Foley, B.J. Bolognese, E. Long III, P.L. Podolin, and P.T. Walsh Airway infiltration of CD4 + CCR6 + Th17 type cells associated with chronic cigarette smoke induced airspace enlargement Immunol Lett 16 121 2008 13 21
36. S.L. Traves, and L.E. Donnelly Th17 cells in airway diseases Curr Mol Med 8 2008 416 426
37. A. Barczyk, W. Pierzchala, and E. Sozañska Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine Respir Med 97 2003 726 733
38. T. Korn, E. Bettelli, M. Oukka, and V.K. Kuchroo IL-17 and Th17 cells Annu Rev Immunol 27 2009 485 517
39. G.G. Brusselle, G.F. Joos, and K.R. Bracke New insights into the immunology of chronic obstructive pulmonary disease Lancet 378 2011 1015 1026
40. B.M. Vanaudenaerde, S.E. Verleden, R. Vos, S.I. De Vleeschauwer, A. Willems-Widyastuti, and R. Geenens Innate and adaptive interleukin-17-producing lymphocytes in chronic inflammatory lung disorders Am J Respir Crit Care Med 183 2011 977 986
41. M.J. Ruddy, F. Shen, J.B. Smith, A. Sharma, and S.L. Gaffen Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment J Leukoc Biol 76 2004 135 144
42. J.L. Curtis, C.M. Freeman, and J.C. Hogg The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research Proc Am Thorac Soc 4 2007 512 521
43. N. Manel, D. Unutmaz, and D.R. Littman The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat Nat Immunol 9 2008 641 649
44. E. Volpe, N. Servant, R. Zollinger, S.I. Bogiatzi, P. Hupé, and E. Barillot A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses Nat Immunol 9 2008 650 657
45. A. Di Stefano, G. Caramori, I. Gnemmi, M. Contoli, C. Vicari, and A. Capelli T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients Clin Exp Immunol 157 2009 316 324
46. A. Kimura, and T. Kishimoto IL-6: regulator of Treg/Th17 balance Eur J Immunol 40 2010 1830 1835