Calhex 231 Ameliorates Cardiac Hypertrophy by Inhibiting Cellular Autophagy in Vivo and in Vitro

Cellular Physiology and Biochemistry

Volumn 36, Issue 4, 2015, Pages 1597-1612

  Liu, Lei ^a   Wang, Chao ^b   Sun, Dianjun ^a   Jiang, Shuangquan ^b   Li, Hong ^a   Zhang, Weihua ^a   Zhao, Yajun ^a   Xi, Yuhui ^a   Shi, Sa ^a   Lu, Fanghao ^a   Tian, Ye ^a   Xu, Changqing ^a   Wang, Lina ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Calcium sensing receptor (CaSR); Calhex 231; Cardiac hypertrophy

Indexed keywords

ANGIOTENSIN II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CALCIUM SENSING RECEPTOR; CALHEX 231; CARDIOVASCULAR AGENT; CASPASE 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; CYCLOHEXYLAMINE DERIVATIVE; MTOR PROTEIN, RAT; N(1)-(4-CHLOROBENZOYL)-N(2)-(1-(1-NAPHTHYL)ETHYL)-1,2-DIAMINOCYCLOHEXANE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; AUTOPHAGY; BODY WEIGHT; CALCIUM CELL LEVEL; CARDIOVASCULAR PARAMETERS; CELL SURVIVAL; CHROMATIN; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART SIZE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERTROPHY INDEX; IN VITRO STUDY; IN VIVO STUDY; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STAINING; TRANSMISSION ELECTRON MICROSCOPY; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; CARDIOMEGALY; DRUG EFFECTS; HEART; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

MAMMALIA; RATTUS; RATTUS NORVEGICUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; BENZAMIDES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CARDIOMEGALY; CYCLOHEXYLAMINES; HEART; MALE; MYOCARDIUM; RATS, WISTAR; RECEPTORS, CALCIUM-SENSING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84936933556     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430322     Document Type: Article

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