Depletion of the ubiquitin-binding adaptor molecule SQSTM1/P62 from macrophages harboring cftr △f508 Mutation Improves the Delivery of Burkholderia cenocepacia to the Autophagic Machinery

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 2049-2058

  Abdulrahman, Basant A ^a,b   Khweek, Arwa Abu ^a   Akhter, Anwari ^a   Caution, Kyle ^a   Tazi, Mia ^a   Hassan, Hoda ^a   Zhang, Yucheng ^a   Rowland, Patrick D ^a   Malhotra, Sankalp ^b   Aeffner, Famke ^a   Davis, Ian C ^a   Valvano, Miguel A ^c,d   Amer, Amal O ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Ein Helwan   (Egypt)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR MOLECULE; ADAPTOR PROTEINS; AUTOPHAGY; BURKHOLDERIA; CAUCASIANS; CELL SURVIVAL; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; EXPRESSION LEVELS; INTRACELLULAR SURVIVAL; LUNG INFLAMMATION; OVER-EXPRESSION; PROTEIN AGGREGATES; UBIQUITIN;

AGGREGATES; MACHINERY; MOLECULES; PROTEINS;

MACROPHAGES;

BECLIN 1; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PROTEIN P62; UBIQUITIN; UBIQUITIN BINDING ADAPTOR MOLECULE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BURKHOLDERIA CENOCEPACIA; CELL SURVIVAL; LYSOSOME; MACROPHAGE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTOPHAGY; BIOLOGICAL MARKERS; BURKHOLDERIA CENOCEPACIA; BURKHOLDERIA INFECTIONS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; MACROPHAGES; MICE; MICE, TRANSGENIC; MICROBIAL VIABILITY; MICROTUBULE-ASSOCIATED PROTEINS; PHAGOSOMES; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; TRANSFECTION; UBIQUITIN;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CENOCEPACIA;

EID: 84872742749     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.411728     Document Type: Article

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