Compound 13, an α1-selective small molecule activator of AMPK, inhibits Helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis

Biochemical and Biophysical Research Communications

Volumn 463, Issue 4, 2015, Pages 510-517

  Zhao, Hangyong ^a   Zhu, Huanghuang ^a   Lin, Zhou ^a   Lin, Gang ^a   Lv, Guoqiang ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

AMPK; Apoptosis; Compound 13; Gastric epithelial cells; Helicobacter pylori; HO 1; Reactive oxygen species (ROS)

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA 1; PROTOPORPHYRIN TIN; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ADENYLATE KINASE; ENZYME ACTIVATOR;

APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HELICOBACTER INFECTION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STOMACH EPITHELIUM; CYTOLOGY; DRUG EFFECTS; GASTRIC MUCOSA; GENETICS; HELICOBACTER PYLORI; METABOLISM; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; PATHOGENICITY; TRANSFORMED CELL LINE;

HELICOBACTER PYLORI;

ADENYLATE KINASE; APOPTOSIS; BASE SEQUENCE; CELL LINE, TRANSFORMED; ENZYME ACTIVATION; ENZYME ACTIVATORS; GASTRIC MUCOSA; HELICOBACTER PYLORI; HUMANS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84936891694     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.05.059     Document Type: Article

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