Synthesis, biological evaluation and mechanism study of a class of benzylideneindanone derivatives as novel anticancer agents

MedChemComm

Volumn 6, Issue 7, 2015, Pages 1318-1327

  Hu, Jinhui ^a   Yan, Jun ^a   Chen, Jie ^a   Pang, Yanqing ^a   Huang, Ling ^a   Li, Xingshu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 AMINO 4 METHOXYBENZYLIDENE) 5,6,7 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 2 (3 BROMO 4 METHOXYBENZYLIDENE) 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 2 (3 FLUORO 4 METHOXYBENZYLIDENE) 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 2 (3 FLUORO 4 METHOXYBENZYLIDENE) 5,6,7 TRIMETHOXY 3,4 DIHYDRONAPHTHALEN 1(2H) ONE; 2 (3 HYDROXY 4 METHOXYBENZYLIDENE) 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 2 (3 HYDROXY 4 METHOXYBENZYLIDENE) 5,6,7 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 2 (3,4 DIMETHOXYBENZYLIDENE) 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 4 (2,3,4 TRIMETHOXYPHENYL)BUTANOIC ACID; 4 OXO 4 (2,3,4 TRIMETHOXYPHENYL)BUTANOIC ACID; 4,5,6 TRIMETHOXY 2 (2,3,4 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 4,5,6 TRIMETHOXY 2 (3,4,5 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 4,5,6 TRIMETHOXY 2 (4 METHOXY 3 NITROBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 4,5,6 TRIMETHOXY 2 (4 METHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6 DIMETHOXY 2 (2,3,4 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6 DIMETHOXY 2 (3,4,5 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6 DIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6,7 TRIMETHOXY 2 (3,4,5 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6,7 TRIMETHOXY 2 (4 METHOXY 3 NITROBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6,7 TRIMETHOXY 2 (4 METHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6,7 TRIMETHOXY 2 (4 METHOXYBENZYLIDENE) 3,4 DIHYDRONAPHTHALEN 1(2H) ONE; 5,6,7 TRIMETHOXY 2,3 DIHYDRO 1H INDEN 1 ONE; 5,6,7 TRIMETHOXY 3,4 DIHYDRONAPHTHALEN 1(2H) ONE; 6 HYDROXY 5 METHOXY 2 (2,3,4 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; 6 HYDROXY 5 METHOXY 2 (3,4,5 TRIMETHOXYBENZYLIDENE) 2,3 DIHYDRO 1H INDEN 1 ONE; ANTINEOPLASTIC AGENT; BENZYLIDENEINDANONE DERIVATIVE; INDANONE DERIVATIVE; UNCLASSIFIED DRUG;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BEL 7402 CELL LINE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; HELA CELL LINE; HUMAN; HUMAN CELL; MDA MB 231 CELL LINE; MTT ASSAY; PC 3 CELL LINE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 84936879571     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c5md00139k     Document Type: Article

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