The Viral CC Chemokine-binding Protein vCCI Inhibits Monocyte Chemoattractant Protein-1 Activity by Masking Its CCR2B-binding Site

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43270-43276

  Beck, Craig G ^b   Studer, Christian ^b   Zuber, Jean François ^b   Jachez Demange, Bénédicte ^b   Manning, Ute ^b   Urfer, Roman ^a  

^a AGY Therapeutics Inc   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; VIRUSES;

BINDING SITES;

PROTEINS;

ALANINE; ARGININE; BINDING PROTEIN; CC CHEMOKINE BINDING PROTEIN; CCR2B RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; VCCI PROTEIN; VIRUS PROTEIN; CALCIUM; CC CHEMOKINE INHIBITOR PROTEIN, VIRAL; CC-CHEMOKINE INHIBITOR PROTEIN, VIRAL; CHEMOKINE RECEPTOR; MONOCLONAL ANTIBODY; MONOCYTE CHEMOATTRACTANT PROTEIN 1 RECEPTOR;

ARTICLE; BINDING SITE; POXVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; VACCINIA VIRUS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; DOSE RESPONSE; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HAMSTER; HUMAN; KINETICS; METABOLISM; MOLECULAR CLONING; MUTATION; PROTEIN BINDING; SURFACE PLASMON RESONANCE; TWO HYBRID SYSTEM;

POXVIRIDAE; VACCINIA VIRUS; VACCINIA;

ALANINE; ANIMALS; ANTIBODIES, MONOCLONAL; ARGININE; BINDING SITES; CALCIUM; CHEMOKINE CCL2; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; RECEPTORS, CHEMOKINE; SURFACE PLASMON RESONANCE; TWO-HYBRID SYSTEM TECHNIQUES; TYROSINE; VIRAL PROTEINS;

EID: 0035900713     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106305200     Document Type: Article

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