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Volumn 21, Issue 25, 2015, Pages 7754-7763

Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats

Author keywords

Autophagy; Ezetimibe; Hepatic steatosis; Nonalcoholic fatty liver disease

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BECLIN 1; CELL PROTEIN; EZETIMIBE; FATTY ACID; GLUCOSE; INSULIN; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; PALMITIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BAFILOMYCIN A1; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; HYPOCHOLESTEROLEMIC AGENT; LIPID; MACROLIDE;

EID: 84936806623     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i25.7754     Document Type: Article
Times cited : (30)

References (50)
  • 1
    • 33747517955 scopus 로고    scopus 로고
    • The epidemiology of nonalcoholic fatty liver disease in adults
    • 16540768
    • Clark JM. The epidemiology of nonalcoholic fatty liver disease in adults. J Clin Gastroenterol 2006;40 Suppl 1:S5-10 [PMID: 16540768 DOI: 10.1097/01.mcg.0000168638.84840.ff]
    • (2006) J Clin Gastroenterol , vol.40 , pp. S5-S10
    • Clark, J.M.1
  • 2
    • 56649123256 scopus 로고    scopus 로고
    • The epidemiology of nonalcoholic fatty liver disease: A global perspective
    • 18956290
    • Lazo M, Clark JM. The epidemiology of nonalcoholic fatty liver disease: a global perspective. Semin Liver Dis 2008;28:339-350 [PMID: 18956290 DOI: 10.1055/s-0028-1091978]
    • (2008) Semin Liver Dis , vol.28 , pp. 339-350
    • Lazo, M.1    Clark, J.M.2
  • 4
    • 84865120793 scopus 로고    scopus 로고
    • Dorothy Hodgkin Lecture 2012: Non-alcoholic fatty liver disease, insulin resistance and ectopic fat: A new problem in diabetes management
    • 22672330
    • Byrne CD. Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management. Diabet Med 2012;29:1098-1107 [PMID: 22672330 DOI: 10.1111/j.1464-5491.2012.03732.x]
    • (2012) Diabet Med , vol.29 , pp. 1098-1107
    • Byrne, C.D.1
  • 7
    • 36549013633 scopus 로고    scopus 로고
    • Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome
    • 18022391
    • Deushi M, Nomura M, Kawakami A, Haraguchi M, Ito M, Okazaki M, Ishii H, Yoshida M. Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS Lett 2007;581:5664-5670 [PMID: 18022391 DOI: 10.1016/j.febslet.2007.11.023]
    • (2007) FEBS Lett , vol.581 , pp. 5664-5670
    • Deushi, M.1    Nomura, M.2    Kawakami, A.3    Haraguchi, M.4    Ito, M.5    Okazaki, M.6    Ishii, H.7    Yoshida, M.8
  • 8
    • 70350468701 scopus 로고    scopus 로고
    • Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance
    • 19654286
    • Nomura M, Ishii H, Kawakami A, Yoshida M. Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance. Am J Physiol Endocrinol Metab 2009;297:E1030-E1038 [PMID: 19654286 DOI: 10.1152/ajpendo.00343.2009]
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. E1030-E1038
    • Nomura, M.1    Ishii, H.2    Kawakami, A.3    Yoshida, M.4
  • 9
    • 84869889959 scopus 로고    scopus 로고
    • Effects of ezetimibe on visceral fat in the metabolic syndrome: A randomised controlled study
    • 23033884
    • Takase H, Dohi Y, Okado T, Hashimoto T, Goto Y, Kimura G. Effects of ezetimibe on visceral fat in the metabolic syndrome: a randomised controlled study. Eur J Clin Invest 2012;42:1287-1294 [PMID: 23033884 DOI: 10.1111/eci.12000]
    • (2012) Eur J Clin Invest , vol.42 , pp. 1287-1294
    • Takase, H.1    Dohi, Y.2    Okado, T.3    Hashimoto, T.4    Goto, Y.5    Kimura, G.6
  • 10
    • 0035572836 scopus 로고    scopus 로고
    • Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice
    • 11742881
    • Davis HR, Compton DS, Hoos L, Tetzloff G. Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice. Arterioscler Thromb Vasc Biol 2001;21:2032-2038 [PMID: 11742881 DOI: 10.1161/hq1201.100260]
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 2032-2038
    • Davis, H.R.1    Compton, D.S.2    Hoos, L.3    Tetzloff, G.4
  • 12
    • 16844376244 scopus 로고    scopus 로고
    • Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia
    • 15671032
    • Davies JP, Scott C, Oishi K, Liapis A, Ioannou YA. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. J Biol Chem 2005;280:12710-12720 [PMID: 15671032 DOI: 10.1074/jbc. M409110200]
    • (2005) J Biol Chem , vol.280 , pp. 12710-12720
    • Davies, J.P.1    Scott, C.2    Oishi, K.3    Liapis, A.4    Ioannou, Y.A.5
  • 13
    • 77952674608 scopus 로고    scopus 로고
    • Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet
    • 20185740
    • Chan DC, Watts GF, Gan SK, Ooi EM, Barrett PH. Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet. Diabetes Care 2010;33:1134-1139 [PMID: 20185740 DOI: 10.2337/dc09-1765]
    • (2010) Diabetes Care , vol.33 , pp. 1134-1139
    • Chan, D.C.1    Watts, G.F.2    Gan, S.K.3    Ooi, E.M.4    Barrett, P.H.5
  • 16
    • 41149120450 scopus 로고    scopus 로고
    • Ezetimibe improves high fat and cholesterol diet-induced nonalcoholic fatty liver disease in mice
    • 18329014
    • Zheng S, Hoos L, Cook J, Tetzloff G, Davis H, Van Heek M, Hwa JJ. Ezetimibe improves high fat and cholesterol diet-induced nonalcoholic fatty liver disease in mice. Eur J Pharmacol 2008;584:118-124 [PMID: 18329014 DOI: 10.1016/j.ejphar.2008.01.045]
    • (2008) Eur J Pharmacol , vol.584 , pp. 118-124
    • Zheng, S.1    Hoos, L.2    Cook, J.3    Tetzloff, G.4    Davis, H.5    Van Heek, M.6    Hwa, J.J.7
  • 18
    • 82255185591 scopus 로고    scopus 로고
    • Therapeutic effects of ezetimibe for non-alcoholic steatohepatitis in fatty liver shionogi-ob/ob mice
    • 21951423
    • Matono T, Koda M, Tokunaga S, Kato J, Sugihara T, Ueki M, Murawaki Y. Therapeutic effects of ezetimibe for non-alcoholic steatohepatitis in fatty liver shionogi-ob/ob mice. Hepatol Res 2011;41:1240-1248 [PMID: 21951423 DOI: 10.1111/j.1872-034X.2011.00888.x]
    • (2011) Hepatol Res , vol.41 , pp. 1240-1248
    • Matono, T.1    Koda, M.2    Tokunaga, S.3    Kato, J.4    Sugihara, T.5    Ueki, M.6    Murawaki, Y.7
  • 19
    • 84891820153 scopus 로고    scopus 로고
    • Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse
    • 23510093
    • Wang X, Sugimoto K, Fujisawa T, Shindo N, Minato S, Kamada Y, Hamano M, Ohishi M, Ikegami H, Rakugi H. Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse. Hepatol Res 2014;44:102-113 [PMID: 23510093 DOI: 10.1111/hepr.12092]
    • (2014) Hepatol Res , vol.44 , pp. 102-113
    • Wang, X.1    Sugimoto, K.2    Fujisawa, T.3    Shindo, N.4    Minato, S.5    Kamada, Y.6    Hamano, M.7    Ohishi, M.8    Ikegami, H.9    Rakugi, H.10
  • 21
    • 78149348442 scopus 로고    scopus 로고
    • Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis
    • 20699423
    • Jia L, Ma Y, Rong S, Betters JL, Xie P, Chung S, Wang N, Tang W, Yu L. Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis. J Lipid Res 2010;51:3135-3144 [PMID: 20699423 DOI: 10.1194/jlr. M006353]
    • (2010) J Lipid Res , vol.51 , pp. 3135-3144
    • Jia, L.1    Ma, Y.2    Rong, S.3    Betters, J.L.4    Xie, P.5    Chung, S.6    Wang, N.7    Tang, W.8    Yu, L.9
  • 22
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • 18305538
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008;451:1069-1075 [PMID: 18305538 DOI: 10.1038/nature06639]
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 23
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • 14699058
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004;15:1101-1111 [PMID: 14699058 DOI: 10.1091/mbc. E03-09-0704]
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 25
    • 34548299555 scopus 로고    scopus 로고
    • Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
    • 17620365
    • Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007;171:513-524 [PMID: 17620365 DOI: 10.2353/ajpath.2007.070188]
    • (2007) Am J Pathol , vol.171 , pp. 513-524
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Yoshimori, T.4    Stolz, D.B.5    Ron, D.6    Yin, X.M.7
  • 28
    • 77955789211 scopus 로고    scopus 로고
    • Altered lipid content inhibits autophagic vesicular fusion
    • 20375270
    • Koga H, Kaushik S, Cuervo AM. Altered lipid content inhibits autophagic vesicular fusion. FASEB J 2010;24:3052-3065 [PMID: 20375270 DOI: 10.1096/fj.09-144519]
    • (2010) FASEB J , vol.24 , pp. 3052-3065
    • Koga, H.1    Kaushik, S.2    Cuervo, A.M.3
  • 29
    • 80054788704 scopus 로고    scopus 로고
    • Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes
    • 21856859
    • Mei S, Ni HM, Manley S, Bockus A, Kassel KM, Luyendyk JP, Copple BL, Ding WX. Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes. J Pharmacol Exp Ther 2011;339:487-498 [PMID: 21856859 DOI: 10.1124/jpet.111.184341]
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 487-498
    • Mei, S.1    Ni, H.M.2    Manley, S.3    Bockus, A.4    Kassel, K.M.5    Luyendyk, J.P.6    Copple, B.L.7    Ding, W.X.8
  • 30
    • 0026722931 scopus 로고
    • Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain
    • 1397718
    • Kawano K, Hirashima T, Mori S, Saitoh Y, Kurosumi M, Natori T. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes 1992;41:1422-1428 [PMID: 1397718 DOI: 10.2337/diab.41.11.1422]
    • (1992) Diabetes , vol.41 , pp. 1422-1428
    • Kawano, K.1    Hirashima, T.2    Mori, S.3    Saitoh, Y.4    Kurosumi, M.5    Natori, T.6
  • 31
    • 0028112936 scopus 로고
    • OLETF (Otsuka Long-Evans Tokushima Fatty) rat: A new NIDDM rat strain
    • 7859627
    • Kawano K, Hirashima T, Mori S, Natori T. OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain. Diabetes Res Clin Pract 1994;24 Suppl: S317-S320 [PMID: 7859627 DOI: 10.1016/0168-8227 (94) 90269-0]
    • (1994) Diabetes Res Clin Pract , vol.24 , pp. S317-S320
    • Kawano, K.1    Hirashima, T.2    Mori, S.3    Natori, T.4
  • 32
    • 36649022057 scopus 로고    scopus 로고
    • Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: Involvement of maintenance of Akt kinase activation
    • 17845508
    • Song Z, Song M, Lee D Y, Liu Y, Deaciuc I V, McClain CJ. Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: involvement of maintenance of Akt kinase activation. Basic Clin Pharmacol Toxicol 2007;101:262-268 [PMID: 17845508 DOI: 10.1111/j.1742-7843.2007.00116.x]
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , pp. 262-268
    • Song, Z.1    Song, M.2    Lee, D.Y.3    Liu, Y.4    Deaciuc, I.V.5    McClain, C.J.6
  • 33
    • 79952032653 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats
    • 21373642
    • Yang SJ, Choi JM, Chae SW, Kim WJ, Park SE, Rhee EJ, Lee WY, Oh KW, Park SW, Kim SW, Park CY. Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. PLoS One 2011;6:e17057 [PMID: 21373642 DOI: 10.1371/journal.pone.0017057]
    • (2011) PLoS One , vol.6 , pp. e17057
    • Yang, S.J.1    Choi, J.M.2    Chae, S.W.3    Kim, W.J.4    Park, S.E.5    Rhee, E.J.6    Lee, W.Y.7    Oh, K.W.8    Park, S.W.9    Kim, S.W.10    Park, C.Y.11
  • 36
    • 0032575551 scopus 로고    scopus 로고
    • Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae
    • 9712845
    • Kametaka S, Okano T, Ohsumi M, Ohsumi Y. Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae. J Biol Chem 1998;273:22284-22291 [PMID: 9712845 DOI: 10.1074/jbc.273.35.22284]
    • (1998) J Biol Chem , vol.273 , pp. 22284-22291
    • Kametaka, S.1    Okano, T.2    Ohsumi, M.3    Ohsumi, Y.4
  • 37
    • 1342321743 scopus 로고    scopus 로고
    • Two ubiquitin-like conjugation systems essential for autophagy
    • 15209383
    • Ohsumi Y, Mizushima N. Two ubiquitin-like conjugation systems essential for autophagy. Semin Cell Dev Biol 2004;15:231-236 [PMID: 15209383 DOI: 10.1016/j.semcdb.2003.12.004]
    • (2004) Semin Cell Dev Biol , vol.15 , pp. 231-236
    • Ohsumi, Y.1    Mizushima, N.2
  • 38
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • 11060023
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-5728 [PMID: 11060023 DOI: 10.1093/emboj/19.21.5720]
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6    Kominami, E.7    Ohsumi, Y.8    Yoshimori, T.9
  • 39
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • 17611390
    • Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007;3:542-545 [PMID: 17611390 DOI: 10.4161/auto.4600]
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 40
    • 79953153831 scopus 로고    scopus 로고
    • Selective degradation of p62 by autophagy
    • 20814791
    • Ichimura Y, Komatsu M. Selective degradation of p62 by autophagy. Semin Immunopathol 2010;32:431-436 [PMID: 20814791 DOI: 10.1007/s00281-010-0220-1]
    • (2010) Semin Immunopathol , vol.32 , pp. 431-436
    • Ichimura, Y.1    Komatsu, M.2
  • 41
    • 79953163093 scopus 로고    scopus 로고
    • Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes
    • 21371430
    • Yang SJ, Choi JM, Kim L, Kim BJ, Sohn JH, Kim WJ, Park SE, Rhee EJ, Lee WY, Oh KW, Park SW, Kim SW, Park CY. Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes. Biochem Biophys Res Commun 2011;407:153-157 [PMID: 21371430 DOI: 10.1016/j.bbrc.2011.02.129]
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 153-157
    • Yang, S.J.1    Choi, J.M.2    Kim, L.3    Kim, B.J.4    Sohn, J.H.5    Kim, W.J.6    Park, S.E.7    Rhee, E.J.8    Lee, W.Y.9    Oh, K.W.10    Park, S.W.11    Kim, S.W.12    Park, C.Y.13
  • 42
    • 84884218057 scopus 로고    scopus 로고
    • Intestinal and hepatic niemann-pick c1-like 1
    • 23991401
    • Park SW. Intestinal and hepatic niemann-pick c1-like 1. Diabetes Metab J 2013;37:240-248 [PMID: 23991401 DOI: 10.4093/dmj.2013.37.4.240]
    • (2013) Diabetes Metab J , vol.37 , pp. 240-248
    • Park, S.W.1
  • 43
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • 9547102
    • Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-845 [PMID: 9547102 DOI: 10.1016/S0016-5085 (98) 70599-2]
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 44
    • 84870995648 scopus 로고    scopus 로고
    • Regulation of lipid stores and metabolism by lipophagy
    • 22595754
    • Liu K, Czaja MJ. Regulation of lipid stores and metabolism by lipophagy. Cell Death Differ 2013;20:3-11 [PMID: 22595754 DOI: 10.1038/cdd.2012.63]
    • (2013) Cell Death Differ , vol.20 , pp. 3-11
    • Liu, K.1    Czaja, M.J.2
  • 45
    • 77954230819 scopus 로고    scopus 로고
    • Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress
    • 20578144
    • Wang Y, Singh R, Xiang Y, Czaja MJ. Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress. Hepatology 2010;52:266-277 [PMID: 20578144 DOI: 10.1002/hep. 23645]
    • (2010) Hepatology , vol.52 , pp. 266-277
    • Wang, Y.1    Singh, R.2    Xiang, Y.3    Czaja, M.J.4
  • 46
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • 20519119
    • Yang L, Li P, Fu S, Calay ES, Hotamisligil GS. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010;11:467-478 [PMID: 20519119 DOI: 10.1016/j.cmet.2010.04.005]
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 50
    • 84896494398 scopus 로고    scopus 로고
    • Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition
    • 24214142
    • Yamamura T, Ohsaki Y, Suzuki M, Shinohara Y, Tatematsu T, Cheng J, Okada M, Ohmiya N, Hirooka Y, Goto H, Fujimoto T. Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition. Hepatology 2014;59:1591-1599 [PMID: 24214142 DOI: 10.1002/hep. 26930]
    • (2014) Hepatology , vol.59 , pp. 1591-1599
    • Yamamura, T.1    Ohsaki, Y.2    Suzuki, M.3    Shinohara, Y.4    Tatematsu, T.5    Cheng, J.6    Okada, M.7    Ohmiya, N.8    Hirooka, Y.9    Goto, H.10    Fujimoto, T.11


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