Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: Involvement of maintenance of Akt kinase activation

Basic and Clinical Pharmacology and Toxicology

Volumn 101, Issue 4, 2007, Pages 262-268

  Song, Zhenyuan ^a   Song, Ming ^a   Lee, David Y W ^b,c   Liu, Yanze ^c,d   Deaciuc, Ion V ^a   McClain, Craig J ^a,b  

^a University of Louisville School of Medicine   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Natural Pharmacia International Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DNA FRAGMENT; GLUTATHIONE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PALMITIC ACID; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SILYMARIN;

ARTICLE; CELL ASSAY; CELL DEATH; CELL LYSATE; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA DEGRADATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LIPID PEROXIDATION; LIVER CELL CULTURE; LIVER PROTECTION; LIVER TOXICITY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROTEIN CONTENT; SUPERNATANT;

CASPASE 3; CELL DEATH; CELL LINE, TUMOR; DNA FRAGMENTATION; ENZYME ACTIVATION; HEPATOCYTES; HUMANS; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; LIVER; MILK THISTLE; PALMITATES; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SILYMARIN;

SILYBUM MARIANUM;

EID: 36649022057     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2007.00116.x     Document Type: Article

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