-
1
-
-
0020769842
-
Vectors for high conditional expression of cloned genes
-
Leplatois, P. & Danchin, A. Vectors for high conditional expression of cloned genes. Biochimie 65, 317-324 (1983).
-
(1983)
Biochimie
, vol.65
, pp. 317-324
-
-
Leplatois, P.1
Danchin, A.2
-
2
-
-
0035491607
-
Conditional control of gene expression in the mouse
-
Lewandoski, M. Conditional control of gene expression in the mouse. Nat. Rev. Genet. 2, 743-755 (2001).
-
(2001)
Nat. Rev. Genet
, vol.2
, pp. 743-755
-
-
Lewandoski, M.1
-
3
-
-
79955016301
-
Conditional expression of the TVA receptor allows clonal analysis of descendents from cre-expressing progenitor cells
-
Beier, K. T., Samson, M. E. S., Matsuda, T. & Cepko, C. L. Conditional expression of the TVA receptor allows clonal analysis of descendents from cre-expressing progenitor cells. Dev. Biol. 353, 309-320 (2011).
-
(2011)
Dev. Biol
, vol.353
, pp. 309-320
-
-
Beier, K.T.1
Samson, M.E.S.2
Matsuda, T.3
Cepko, C.L.4
-
4
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
Lois, C., Hong, E. J., Pease, S., Brown, E. J. & Baltimore, D. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295, 868-872 (2002).
-
(2002)
Science
, vol.295
, pp. 868-872
-
-
Lois, C.1
Hong, E.J.2
Pease, S.3
Brown, E.J.4
Baltimore, D.5
-
5
-
-
84870835237
-
Engraftment potential of adipose tissue-derived human mesenchymal stem cells after transplantation in the fetal rabbit
-
Martinez-Gonzalez, I., Moreno, R., Petriz, J., Gratacos, E. & Aran, J. M. Engraftment potential of adipose tissue-derived human mesenchymal stem cells after transplantation in the fetal rabbit. Stem Cells Dev. 21, 3270-3277 (2012).
-
(2012)
Stem Cells Dev
, vol.21
, pp. 3270-3277
-
-
Martinez-Gonzalez, I.1
Moreno, R.2
Petriz, J.3
Gratacos, E.4
Aran, J.M.5
-
6
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
7
-
-
0030917202
-
ONYX-015, an E1B gene-attenuated adenovirus, causes tumorspecific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
-
Heise, C. et al. ONYX-015, an E1B gene-attenuated adenovirus, causes tumorspecific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat. Med. 3, 639-645 (1997).
-
(1997)
Nat. Med
, vol.3
, pp. 639-645
-
-
Heise, C.1
-
8
-
-
0026773397
-
Tissue-specific and development-specific expression of the human phenylalanine-hydroxylase chloramphenicol acetyltransferase fusion gene in transgenic mice
-
Wang, Y. B. et al. Tissue-specific and development-specific expression of the human phenylalanine-hydroxylase chloramphenicol acetyltransferase fusion gene in transgenic mice. J. Biol. Chem. 267, 15105-15110 (1992).
-
(1992)
J. Biol. Chem
, vol.267
, pp. 15105-15110
-
-
Wang, Y.B.1
-
9
-
-
0028795918
-
The upstream promoter element of the glucagon gene G1, confers pancreatic alpha cell-specific expression
-
Morel, C., Cordierbussat, M. & Philippe, J. The upstream promoter element of the glucagon gene, G1, confers pancreatic alpha cell-specific expression. J. Biol. Chem. 270, 3046-3055 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 3046-3055
-
-
Morel, C.1
Cordierbussat, M.2
Philippe, J.3
-
10
-
-
0242401835
-
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
-
Gong, S. C. et al. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425, 917-925 (2003).
-
(2003)
Nature
, vol.425
, pp. 917-925
-
-
Gong, S.C.1
-
11
-
-
84979459774
-
Developmental context determines latency of MYC-induced tumorigenesis
-
Beer, S. et al. Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol. 2, 1785-1798 (2004).
-
(2004)
PLoS Biol
, vol.2
, pp. 1785-1798
-
-
Beer, S.1
-
12
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher, D. W. & Bishop, J. M. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
13
-
-
84857658829
-
Transcriptional code and disease map for adult retinal cell types
-
Siegert, S. et al. Transcriptional code and disease map for adult retinal cell types. Nat. Neurosci. 15, 487-495 (2012).
-
(2012)
Nat. Neurosci
, vol.15
, pp. 487-495
-
-
Siegert, S.1
-
14
-
-
0034175969
-
Gene therapy: Designer promoters for tumour targeting
-
Nettelbeck, D. M., Jerome, V. & Muller, R. Gene therapy: designer promoters for tumour targeting. Trends Genet. 16, 174-181 (2000).
-
(2000)
Trends Genet
, vol.16
, pp. 174-181
-
-
Nettelbeck, D.M.1
Jerome, V.2
Muller, R.3
-
15
-
-
36849060584
-
Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
-
Brown, B. D. et al. Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state. Nat. Biotechnol. 25, 1457-1467 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1457-1467
-
-
Brown, B.D.1
-
16
-
-
65449143961
-
Inducible site-specific recombination in neural stem/progenitor cells
-
Chen, J., Kwon, C. H., Lin, L., Li, Y. J. & Parada, L. F. Inducible site-specific recombination in neural stem/progenitor cells. Genesis 47, 122-131 (2009).
-
(2009)
Genesis
, vol.47
, pp. 122-131
-
-
Chen, J.1
Kwon, C.H.2
Lin, L.3
Li, Y.J.4
Parada, L.F.5
-
17
-
-
84874529329
-
Alpha-fetoprotein promoter-driven Cre/LoxP-switched RNA interference for hepatocellular carcinoma tissue-specific target therapy
-
Peng, Y. F. et al. Alpha-fetoprotein promoter-driven Cre/LoxP-switched RNA interference for hepatocellular carcinoma tissue-specific target therapy. PLoS ONE 8, e53072 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e53072
-
-
Peng, Y.F.1
-
18
-
-
0032692949
-
Temporal spatial, and cell type-specific control of CRE-mediated DNA recombination in transgenic mice
-
Utomo, A. R. H., Nikitin, A. Y. & Lee, W. H. Temporal, spatial, and cell type-specific control of CRE-mediated DNA recombination in transgenic mice. Nat. Biotechnol. 17, 1091-1096 (1999).
-
(1999)
Nat. Biotechnol
, vol.17
, pp. 1091-1096
-
-
Utomo, A.R.H.1
Nikitin, A.Y.2
Lee, W.H.3
-
19
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
Gardner, T. S., Cantor, C. R. & Collins, J. J. Construction of a genetic toggle switch in Escherichia Coli Nature 403, 339-342 (2000).
-
(2000)
Nature
, vol.403
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
20
-
-
33744509927
-
Engineering life: Building a FAB for biology
-
Baker, D. et al. Engineering life: building a FAB for biology. Sci. Am. 294, 44-51 (2006).
-
(2006)
Sci. Am
, vol.294
, pp. 44-51
-
-
Baker, D.1
-
21
-
-
0034688173
-
A synthetic oscillatory network of transcriptional regulators
-
Elowitz, M. B. & Leibler, S. A synthetic oscillatory network of transcriptional regulators. Nature 403, 335-338 (2000).
-
(2000)
Nature
, vol.403
, pp. 335-338
-
-
Elowitz, M.B.1
Leibler, S.2
-
22
-
-
34447310821
-
A universal RNAi-based logic evaluator that operates in mammalian cells
-
Rinaudo, K. et al. A universal RNAi-based logic evaluator that operates in mammalian cells. Nat. Biotechnol. 25, 795-801 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 795-801
-
-
Rinaudo, K.1
-
23
-
-
77950676224
-
Self-sufficient control of urate homeostasis in mice by a synthetic circuit
-
Kemmer, C. et al. Self-sufficient control of urate homeostasis in mice by a synthetic circuit. Nat. Biotechnol. 28, 355-360 (2010).
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 355-360
-
-
Kemmer, C.1
-
24
-
-
77952679687
-
Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems
-
Chen, Y. Y., Jensen, M. C. & Smolke, C. D. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. Proc. Natl Acad. Sci. USA 107, 8531-8536 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 8531-8536
-
-
Chen, Y.Y.1
Jensen, M.C.2
Smolke, C.D.3
-
25
-
-
79959514813
-
A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
-
Ye, H. F., Daoud-El Baba, M., Peng, R. W. & Fussenegger, M. A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice. Science 332, 1565-1568 (2011).
-
(2011)
Science
, vol.332
, pp. 1565-1568
-
-
Ye, H.F.1
Daoud-El Baba, M.2
Peng, R.W.3
Fussenegger, M.4
-
26
-
-
84863454666
-
Programmable single-cell mammalian biocomputers
-
Auslander, S., Auslander, D., Muller, M., Wieland, M. & Fussenegger, M. Programmable single-cell mammalian biocomputers. Nature 487, 123-127 (2012).
-
(2012)
Nature
, vol.487
, pp. 123-127
-
-
Auslander, S.1
Auslander, D.2
Muller, M.3
Wieland, M.4
Fussenegger, M.5
-
27
-
-
77956431677
-
Rationally designed logic integration of regulatory signals in mammalian cells
-
Leisner, M., Bleris, L., Lohmueller, J., Xie, Z. & Benenson, Y. Rationally designed logic integration of regulatory signals in mammalian cells. Nat. Nanotechnol. 5, 666-670 (2010).
-
(2010)
Nat. Nanotechnol
, vol.5
, pp. 666-670
-
-
Leisner, M.1
Bleris, L.2
Lohmueller, J.3
Xie, Z.4
Benenson, Y.5
-
28
-
-
80052456127
-
Multi-input RNAi-based logic circuit for identification of specific cancer cells
-
Xie, Z., Wroblewska, L., Prochazka, L., Weiss, R. & Benenson, Y. Multi-input RNAi-based logic circuit for identification of specific cancer cells. Science 333, 1307-1311 (2011).
-
(2011)
Science
, vol.333
, pp. 1307-1311
-
-
Xie, Z.1
Wroblewska, L.2
Prochazka, L.3
Weiss, R.4
Benenson, Y.5
-
29
-
-
84863644753
-
Synthetic memory circuits for tracking human cell fate
-
Burrill, D. R., Inniss, M. C., Boyle, P. M. & Silver, P. A. Synthetic memory circuits for tracking human cell fate. Gene Dev. 26, 1486-1497 (2012).
-
(2012)
Gene Dev
, vol.26
, pp. 1486-1497
-
-
Burrill, D.R.1
Inniss, M.C.2
Boyle, P.M.3
Silver, P.A.4
-
30
-
-
84874619884
-
Transferring a synthetic gene circuit from yeast to mammalian cells
-
Nevozhay, D., Zal, T. & Balazsi, G. Transferring a synthetic gene circuit from yeast to mammalian cells. Nat. Commun. 4, 1451 (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 1451
-
-
Nevozhay, D.1
Zal, T.2
Balazsi, G.3
-
31
-
-
48249141397
-
A synthetic mammalian gene circuit reveals antituberculosis compounds
-
Weber, W. et al. A synthetic mammalian gene circuit reveals antituberculosis compounds. Proc. Natl Acad. Sci. USA 105, 9994-9998 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9994-9998
-
-
Weber, W.1
-
32
-
-
4344670936
-
Bow ties, metabolism and disease
-
Csete, M. & Doyle, J. Bow ties, metabolism and disease. Trends Biotechnol. 22, 446-450 (2004).
-
(2004)
Trends Biotechnol
, vol.22
, pp. 446-450
-
-
Csete, M.1
Doyle, J.2
-
33
-
-
84865304769
-
A sensitive switch for visualizing natural gene silencing in single cells
-
Haynes, K. A., Ceroni, F., Flicker, D., Youngers, A. & Silver, P. A. A sensitive switch for visualizing natural gene silencing in single cells. ACS Synth. Biol. 1, 99-106 (2012).
-
(2012)
ACS Synth. Biol
, vol.1
, pp. 99-106
-
-
Haynes, K.A.1
Ceroni, F.2
Flicker, D.3
Youngers, A.4
Silver, P.A.5
-
34
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
-
35
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
Yoo, A. S. et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476, 228-231 (2011).
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
-
36
-
-
79953881831
-
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
-
Anokye-Danso, F. et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8, 376-388 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
-
37
-
-
84863115641
-
Maintenance of muscle stem-cell quiescence by microRNA-489
-
Cheung, T. H. et al. Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482, 524-528 (2012).
-
(2012)
Nature
, vol.482
, pp. 524-528
-
-
Cheung, T.H.1
-
38
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf, P. et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129, 1401-1414 (2007).
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
-
39
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
-
40
-
-
66249120339
-
MicroRNA profiling of human-induced pluripotent stem cells
-
Wilson, K. D. et al. MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells Dev. 18, 749-757 (2009).
-
(2009)
Stem Cells Dev
, vol.18
, pp. 749-757
-
-
Wilson, K.D.1
-
41
-
-
84862922523
-
Cell-type-based analysis of MicroRNA profiles in the mouse brain
-
He, M. et al. Cell-type-based analysis of MicroRNA profiles in the mouse brain. Neuron 73, 35-48 (2012).
-
(2012)
Neuron
, vol.73
, pp. 35-48
-
-
He, M.1
-
42
-
-
0036158916
-
Codon-improved Cre recombinase (iCre) expression in the mouse
-
Shimshek, D. R. et al. Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis 32, 19-26 (2002).
-
(2002)
Genesis
, vol.32
, pp. 19-26
-
-
Shimshek, D.R.1
-
43
-
-
33947647023
-
High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells
-
Raymond, C. S. & Soriano, P. High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. PLoS ONE 2, e162 (2007).
-
(2007)
PLoS ONE
, vol.2
, pp. e162
-
-
Raymond, C.S.1
Soriano, P.2
-
44
-
-
58149265300
-
Mutational derivatives of PhiC31 integrase with increased efficiency and specificity
-
Keravala, A. et al. Mutational derivatives of PhiC31 integrase with increased efficiency and specificity. Mol. Ther. 17, 112-120 (2009).
-
(2009)
Mol. Ther
, vol.17
, pp. 112-120
-
-
Keravala, A.1
-
45
-
-
4244176946
-
A single vector containing modified cre recombinase and LOX recombination sequences for inducible tissue-specific amplification of gene expression
-
Kaczmarczyk, S. J. & Green, J. E. A single vector containing modified cre recombinase and LOX recombination sequences for inducible tissue-specific amplification of gene expression. Nucleic Acids Res. 29, e56 (2001).
-
(2001)
Nucleic Acids Res
, vol.29
, pp. e56
-
-
Kaczmarczyk, S.J.1
Green, J.E.2
-
46
-
-
49049099862
-
A FLEX switch targets channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping
-
Atasoy, D., Aponte, Y., Su, H. H. & Sternson, S. M. A FLEX switch targets channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J. Neurosci. 28, 7025-7030 (2008).
-
(2008)
J. Neurosci
, vol.28
, pp. 7025-7030
-
-
Atasoy, D.1
Aponte, Y.2
Su, H.H.3
Sternson, S.M.4
-
47
-
-
77956123402
-
Multiplexing RMCE: Versatile extensions of the Flp-recombinase-mediated cassette-exchange technology
-
Turan, S., Kuehle, J., Schambach, A., Baum, C. & Bode, J. Multiplexing RMCE: Versatile extensions of the Flp-recombinase-mediated cassette-exchange technology. J. Mol. Biol. 402, 52-69 (2010).
-
(2010)
J. Mol. Biol
, vol.402
, pp. 52-69
-
-
Turan, S.1
Kuehle, J.2
Schambach, A.3
Baum, C.4
Bode, J.5
-
48
-
-
0042964105
-
Novel promoter/transactivator configurations for macrolide-and streptograminresponsive transgene expression in mammalian cells
-
Weber, W., Kramer, B. P., Fux, C., Keller, B. & Fussenegger, M. Novel promoter/transactivator configurations for macrolide-and streptograminresponsive transgene expression in mammalian cells. J. Gene Med. 4, 676-686 (2002).
-
(2002)
J. Gene Med
, vol.4
, pp. 676-686
-
-
Weber, W.1
Kramer, B.P.2
Fux, C.3
Keller, B.4
Fussenegger, M.5
-
49
-
-
0036714926
-
Macrolide-based transgene control in mammalian cells and mice
-
Weber, W. et al. Macrolide-based transgene control in mammalian cells and mice. Nat. Biotechnol. 20, 901-907 (2002).
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 901-907
-
-
Weber, W.1
-
50
-
-
0035979738
-
Regulation of transcriptional activation domain function by ubiquitin
-
Salghetti, S. E., Caudy, A. A., Chenoweth, J. G. & Tansey, W. P. Regulation of transcriptional activation domain function by ubiquitin. Science 293, 1651-1653 (2001).
-
(2001)
Science
, vol.293
, pp. 1651-1653
-
-
Salghetti, S.E.1
Caudy, A.A.2
Chenoweth, J.G.3
Tansey, W.P.4
-
51
-
-
2942715351
-
VP16 and ubiquitin: Binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes
-
Kurosu, T. & Peterlin, B. M. VP16 and ubiquitin: Binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes. Curr. Biol. 14, 1112-1116 (2004).
-
(2004)
Curr. Biol
, vol.14
, pp. 1112-1116
-
-
Kurosu, T.1
Peterlin, B.M.2
-
52
-
-
84964312492
-
Digital switching in a biosensor circuit via programmable timing of gene availability
-
Lapique, N. & Benenson, Y. Digital switching in a biosensor circuit via programmable timing of gene availability. Nat. Chem. Biol. doi: 10.1038/NCHEMBIO.1680 (2014).
-
(2014)
Nat. Chem. Biol.
-
-
Lapique, N.1
Benenson, Y.2
-
53
-
-
0033767759
-
Streptogramin-based gene regulation systems for mammalian cells
-
Fussenegger, M. et al. Streptogramin-based gene regulation systems for mammalian cells. Nat. Biotechnol. 18, 1203-1208 (2000).
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 1203-1208
-
-
Fussenegger, M.1
-
54
-
-
79957946108
-
Scaling up digital circuit computation with DNA strand displacement cascades
-
Qian, L. L. & Winfree, E. Scaling up digital circuit computation with DNA strand displacement cascades. Science 332, 1196-1201 (2011).
-
(2011)
Science
, vol.332
, pp. 1196-1201
-
-
Qian, L.L.1
Winfree, E.2
-
55
-
-
84882676796
-
Retroactivity controls the temporal dynamics of gene transcription
-
Jayanthi, S., Nilgiriwala, K. S. & Del Vecchio, D. Retroactivity controls the temporal dynamics of gene transcription. ACS Synth. Biol. 2, 431-441 (2013).
-
(2013)
ACS Synth. Biol
, vol.2
, pp. 431-441
-
-
Jayanthi, S.1
Nilgiriwala, K.S.2
Del Vecchio, D.3
|