Engraftment potential of adipose tissue-derived human mesenchymal stem cells after transplantation in the fetal rabbit

Stem Cells and Development

Volumn 21, Issue 18, 2012, Pages 3270-3277

  Martínez González, Itziar ^a   Moreno, Rafael ^a   Petriz, Jordi ^b   Gratacós, Eduard ^c   Aran, Josep M ^a  

^a HOSPITAL DURAN I REYNALS   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN;

ADIPOSE TISSUE; ADIPOSE TISSUE DERIVED MESENCHYMAL STEM CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENGRAFTMENT; FEMALE; FETUS; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROCHIMERISM; NONHUMAN; PRIORITY JOURNAL; RABBIT; SAFETY; SURVIVAL RATE; TREATMENT OUTCOME; XENOTRANSPLANTATION;

ADIPOSE TISSUE; ADULT STEM CELLS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL DIFFERENTIATION; FEMALE; FETUS; GENETIC ENGINEERING; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LYMPHOCYTE CULTURE TEST, MIXED; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; RABBITS; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 84870835237     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0032     Document Type: Article

References (29)

1. Mehta V, K Abi Nader, S Waddington and AL David. (2011). Organ targeted prenatal gene therapy -how far are we? Prenat Diagn 31:720-734.
2. Gonzaga S, T Henriques-Coelho, M Davey, PW Zoltick, AF Leite-Moreira, J Correia-Pinto and AW Flake. (2008). Cystic adenomatoid malformations are induced by localized FGF10 overexpression in fetal rat lung. Am J Respir Cell Mol Biol 39:346-355.
3. Themis M, SN Waddington, M Schmidt, C von Kalle, Y Wang, F Al-Allaf, LG Gregory, M Nivsarkar, M Themis, et al. (2005). Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. Mol Ther 12:763-771.
4. Park PJ, E Colletti, F Ozturk, JA Wood, J Tellez, G Almeida-Porada and C Porada. (2009). Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep. Hum Gene Ther 20:201-215.
5. Cumano A and I Godin. (2007). Ontogeny of the hematopoietic system. Annu Rev Immunol 25:745-785.
6. Roybal JL, MT Santore and AW Flake. (2010). Stem cell and genetic therapies for the fetus. Semin Fetal Neonatal Med 15:46-51.
7. Almeida-Porada G, CD Porada, N Tran and ED Zanjani. (2000). Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation. Blood 95:3620-3627.
8. Mosna F, L Sensebé and M Krampera. (2010). Human bone marrow and adipose tissue mesenchymal stem cells: a user's guide. Stem Cells Dev 19:1449-1470.
9. Ghannam S, C Bouffi, F Djouad, C Jorgensen and D Noel. (2010). Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications. Stem Cell Res Ther 1:2.
10. Bernardo ME, F Locatelli and WE Fibbe. (2009). Mesenchymal stromal cells. Ann New York Acad Sci 1176:101-117.
11. Chen CP, SH Liu, JP Huang, JD Aplin, YH Wu, PC Chen, CS Hu, CC Ko, MY Lee and CY Chen. (2009). Engraftment potential of human placenta-derived mesenchymal stem cells after in utero transplantation in rats. Hum Reprod 24:154-165.
12. Ersek A, JS Pixley, AD Goodrich, CD Porada, G Almeida-Porada, DS Thain and ED Zanjani. (2010). Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells. Exp Hematol 38:311-320.
13. MacKenzie TC and AW Flake. (2001). Multilineage differentiation of human MSC after in utero transplantation. Cytotherapy 3:403-405.
14. Moreno R, I Marti'nez-Gonza'lez, M Rosal, M Nadal, J Petriz, E Gratacó s and JM Aran. (2012). Fetal liver-derived mesenchymal stem cell engraftment after allogeneic in utero transplantation into rabbits. Stem Cells Dev 21:284-295.
15. Moreno R, I Marti'nez, J Petriz, M Nadal, X Tintoré, JR Gonzalez, E Gratacó s and JM Aran. (2011). The b-interferon scaffold attachment region confers high-level transgene expression and avoids extinction by epigenetic modifications of integrated provirus in adipose tissue-derived human mesenchymal stem cells. Tissue Eng Part C 17:275-287.
16. Moreno R, M Rosal, I Marti'nez, F Vilardell, JR Gonzalez, J Petriz, E Hernandez-Andrade, E Gratacó s and JM Aran. (2008). Restricted transgene persistence after lentiviral vector-mediated fetal gene transfer in the pregnant rabbit model. J Gene Med 10:951-964.
17. Moreno R, M Rosal, L Cabrero, E Gratacó s and JM Aran. (2005). Feasibility of retroviral vector-mediated in utero gene transfer to the fetal rabbit. Fetal Diagn Ther 20:485-493.
18. Pittenger MF, AM Mackay, SC Beck, RK Jaiswal, R Douglas, JD Mosca, MA Moorman, DW Simonetti, S Craig and DR Marshak. (1999). Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147.
19. Bunnell BA, M Flaat, C Gagliardi, B Patel and C Ripoll. (2008). Adipose-derived stem cells: isolation, expansion and differentiation. Methods 45:115-120.
20. Buckley SMK, SN Waddington, S Jezzard, L Lawrence, H Schneider, MV Holder, M Themis and C Coutelle. (2005). Factors influencing adenovirus-mediated airway transduction in fetal mice. Mol Ther 12:484-492.
21. Westgren M. (2006). In utero stem cell transplantation. Semin Reprod Med 24:348-357.
22. DelaRosa O, B Sa'nchez-Correa, S Morgado, C Rami'rez, B Del Ri'o, R Menta, E Lombardo, R Tarazona and JG Casado. (2011). Human adipose-derived stem cells impair naturalkiller cell function and exhibit low susceptibility to natural killer-mediated lysis. Stem Cells Dev 21:1333-1343.
23. Kim HB, AF Shaaban, EY Yang, KW Liechty and AW Flake. (1998) Microchimerism and tolerance after in utero bone marrow transplantation in mice. J Surg Res 77:1-5.
24. Durkin ET, KA Jones, D Rajesh and AF Shaaban. (2008). Early chimerism threshold predicts sustained engraftment and NK-cell tolerance in prenatal allogeneic chimeras. Blood 112:5245-5253.
25. Hofmann A, B Kessler, S Ewerling, A Kabermann, G Brem, E Wolf and A Pfeifer. (2006). Epigenetic regulation of lentiviral transgene vectors in a large animal model. Mol Ther 13:59-66.
26. Herbst F, CR Ball, F Tuorto, A Nowrouzi, W Wang, O Zavidij, SM Dieter, S Fessler, F van der Hoeven, et al. (2012). Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo. Mol Ther 20:1014-1021.
27. Giles KE, H Gowher, R Ghirlando, C Jin and G Felsenfeld. (2010). Chromatin boundaries, insulators, and long-range interactions in the nucleus. Cold Spring Harb Symp Quant Biol 75:79-85.
28. Carrier E, TH Lee, MP Busch and MJ Cowan. (1995). Induction of tolerance in nondefective mice after in utero transplantation of major histocompatibility complexmismatched fetal hematopoietic stem cells. Blood 86:4681-4690.
29. Hajdu K, S Tanigawara, LK McLean, MJ Cowan and MS Golbus. (1996). In utero allogeneic hematopoietic stem cell transplantation to induce tolerance. Fetal Diagn Ther 11: 241-248.