On the feasibility of growth-coupled product synthesis in microbial strains

Metabolic Engineering

Volumn 30, Issue , 2015, Pages 166-178

  Klamt, Steffen ^a   Mahadevan, Radhakrishnan ^b,c  

^a MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Computational strain design; Elementary (flux) modes; Elementary (flux) vectors; Escherichia coli; Growth coupled product synthesis; Yield space

Indexed keywords

BIOMASS; BIOMOLECULES; ECOLOGY; ESCHERICHIA COLI; METABOLIC ENGINEERING; METABOLISM; METABOLITES; STRAIN; VECTOR SPACES;

CONSTRAINT-BASED MODELING; ELEMENTARY (FLUX) MODES; INHOMOGENEOUS PROBLEMS; INTERVENTION STRATEGY; MAINTENANCE REQUIREMENT; MICROBIAL PRODUCTION; PRODUCT SYNTHESIS; YIELD SPACE;

PRODUCT DESIGN;

ADENOSINE TRIPHOSPHATE; CARBON;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BIOMASS PRODUCTION; ESCHERICHIA COLI; FEASIBILITY STUDY; METABOLITE; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS; BIOLOGICAL MODEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

ESCHERICHIA COLI;

ADENOSINE TRIPHOSPHATE; ESCHERICHIA COLI; MODELS, BIOLOGICAL;

EID: 84935478514     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.05.006     Document Type: Article

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