Dual drug delivery from vitamin e loaded contact lenses for glaucoma therapy

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 94, Issue , 2015, Pages 312-321

  Hsu, Kuan Hui ^a   Carbia, Blanca E ^b   Plummer, Caryn ^b   Chauhan, Anuj ^a  

^a University of Florida   (United States)

^b University of Florida   (United States)

Author keywords

Combination therapy; Contact lenses; Dorzolamide; Glaucoma; Timolol; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; EYE DROPS; TIMOLOL; ANTIHYPERTENSIVE AGENT; DELAYED RELEASE FORMULATION; SULFONAMIDE; THIOPHENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTACT LENS; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG SAFETY; IN VITRO STUDY; INTRAOCULAR PRESSURE; NONHUMAN; OPEN ANGLE GLAUCOMA; ANIMAL; BIOAVAILABILITY; COMBINATION DRUG THERAPY; DELAYED RELEASE FORMULATION; DOG; DRUG EFFECTS; GLAUCOMA, OPEN-ANGLE; HEART RATE; METABOLISM;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOLOGICAL AVAILABILITY; CONTACT LENSES; DELAYED-ACTION PREPARATIONS; DOGS; DRUG LIBERATION; DRUG THERAPY, COMBINATION; GLAUCOMA, OPEN-ANGLE; HEART RATE; INTRAOCULAR PRESSURE; OPHTHALMIC SOLUTIONS; SULFONAMIDES; THIOPHENES; TIMOLOL; VITAMIN E;

EID: 84934949820     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.06.001     Document Type: Article

References (59)

1. H.A. Quigley, and A.T. Broman The number of people with glaucoma worldwide in 2010 and 2020 Brit. J. Ophthalmol. 90 2006 262 267
2. S. Resnikoff, D. Pascolini, D. Etya'ale, I. Kocur, R. Pararajasegaram, G.P. Pokharel, and S.P. Mariotti Global data on visual impairment in the year 2002 B. World Health Organ. 82 2004 844 851
3. NEI, Report of the Glaucoma Panel, Fall, 1998. < http://www.nei.nih.gov/resources/strategicplans/neiplan/frm-glaucoma.asp > (accessed 20.08.14).
4. C. Le Bourlais, L. Acar, H. Zia, P.A. Sado, T. Needham, and R. Leverge Ophthalmic drug delivery systems - recent advances Prog. Retin. Eye Res. 17 1998 33 58
5. D. Achouri, K. Alhanout, P. Piccerelle, and V. Andrieu Recent advances in ocular drug delivery Drug Dev. Ind. Pharm. 39 2012 1 19
6. J.H. Gurwitz, R.J. Glynn, M. Monane, D.E. Everitt, D. Gilden, N. Smith, and J. Avorn Treatment for glaucoma: adherence by the elderly Am. J. Public Health 83 1993 711 716
7. B. Sleath, A.L. Robin, D. Covert, J.E. Byrd, G. Tudor, and B. Svarstad Patient-reported behavior and problems in using glaucoma medications Ophthalmology 113 2006 431 436
8. J.C. Tsai A comprehensive perspective on patient adherence to topical glaucoma therapy Ophthalmology 116 2009 S30 S36
9. C.C. Li, and A. Chauhan Modeling ophthalmic drug delivery by soaked contact lenses Ind. Eng. Chem. Res. 45 2006 3718 3734
10. D.M. Maurice Structures and fluids involved in the penetration of topically applied drugs Int. Ophthalmol. Clin. 20 1980 7 20
11. C.C.S. Karlgard, N.S. Wong, L.W. Jones, and C. Moresoli In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials Int. J. Pharm. 257 2003 141 151
12. A. Boone, A. Hui, and L. Jones Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses Eye Contact Lens 35 2009 260 267
13. L.C. Bengani, K.H. Hsu, S. Gause, and A. Chauhan Contact lenses as a platform for ocular drug delivery Expert Opin. Drug Del. 10 2013 1483 1496
14. C. Alvarez-Lorenzo, H. Hiratani, and A. Concheiro Contact lenses for drug delivery Am. J. Drug Del. 4 2006 131 151
15. L. Xinming, C. Yingde, A.W. Lloyd, S.V. Mikhalovsky, S.R. Sandeman, C.A. Howel, and L. Liewen Polymeric hydrogels for novel contact lens-based ophthalmic drug delivery systems: a review Cont. Lens Anterior Eye 31 2008 57 64
16. K.-H. Hsu, S. Gause, and A. Chauhan Review of ophthalmic drug delivery by contact lenses J. Drug Deliv. Sci. Technol. 24 2014 000-000
17. C.C. Peng, J. Kim, and A. Chauhan Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing vitamin E diffusion barriers Biomaterials 31 2010 4032 4047
18. J. Kim, C.C. Peng, and A. Chauhan Extended release of dexamethasone from silicone-hydrogel contact lenses containing vitamin E J. Control. Release 148 2010 110 116
19. C.C. Peng, A. Ben-Shlomo, E.O. Mackay, C.E. Plummer, and A. Chauhan Drug delivery by contact lens in spontaneously glaucomatous dogs Curr. Eye Res. 37 2012 204 211
20. C.C. Peng, M.T. Burke, B.E. Carbia, C. Plummer, and A. Chauhan Extended drug delivery by contact lenses for glaucoma therapy J. Control. Release 162 2012 152 158
21. C.C. Peng, and A. Chauhan Extended cyclosporine delivery by silicone-hydrogel contact lenses J. Control. Release 154 2011 267 274
22. C.C. Peng, M.T. Burke, and A. Chauhan Transport of topical anesthetics in vitamin E loaded silicone hydrogel contact lenses Langmuir 28 2012 1478 1487
23. K.-H. Hsu, R.C. Fentzke, and A. Chauhan Feasibility of corneal drug delivery of cysteamine using vitamin E modified silicone-hydrogel contact lenses Eur. J. Pharm. Biopharm. 85 2013 531 540
24. K.-H. Hsu, P. Lazon de la Jara, A. Ariyavidana, J. Watling, B. Holden, Q. Garrett, and A. Chauhan Release of betaine and dexpanthenol from vitamin E modified silicone-hydrogel contact lenses Curr. Eye Res. 40 2014 267 273
25. J.E. Frampton, and C.M. Perry Topical dorzolamide 2%/timolol 0.5% ophthalmic solution Drug Aging 23 2006 977 995
26. C.E. Plummer, E.O. MacKay, and K.N. Gelatt Comparison of the effects of topical administration of a fixed combination of dorzolamide-timolol to monotherapy with timolol or dorzolamide on IOP, pupil size, and heart rate in glaucomatous dogs Vet. Ophthalmol. 9 2006 245 249
27. J.E. Boyle, K. Ghosh, D.K. Gieser, and I.A. Adamsons A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide Ophthalmology 105 1998 1945 1951
28. C.M. Clineschmidt, R.D. Williams, E. Snyder, and I.A. Adamsons A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide Ophthalmology 105 1998 1952 1959
29. R.D. Fechtner, and T. Realini Fixed combinations of topical glaucoma medications Curr. Opin. Ophthalmol. 15 2004 132 135
30. K. Strohmaier, E. Snyder, H. DuBiner, and I. Adamsons The efficacy and safety of the dorzolamide - timolol combination versus the concomitant administration of its components Ophthalmology 105 1998 1936 1944
31. J. Bacharach, M.F. Delgado, and A.G. Iwach Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide J. Ocul. Pharmacol. Ther. 19 2003 93 96
32. D. Ormrod, and K. McClellan Topical dorzolamide 2%/timolol 0.5% Drug Aging 17 2000 477 496
33. D.G. Kaplan, S. Pazirandeh, M.M. Alvarado, L. Attal, Process for Making Soft Contact and Intraocular Lenses with an Esterifiable Carboxyl-Containing Polymer, U.S. Patent 4,668,446 A, 1987.
34. O. Wichterle, Method of manufacturing soft and flexible contact lenses, in: Google Patents, 1970.
35. D.G. Vanderlaan, D.C. Turner, M.V. Hargiss, A.C. Maiden, R.N. Love, J.D. Ford, F.F. Molock, R.B. Steffen, G.A. Hill, A. Alli, Soft Contact Lenses, U.S. Patent 6,943,203 B2, 2005.
36. S.L. Willis, J.L. Court, R.P. Redman, J.-H. Wang, S.W. Leppard, V.J. O'Byrne, S.A. Small, A.L. Lewis, S.A. Jones, and P.W. Stratford A novel phosphorylcholine-coated contact lens for extended wear use Biomaterials 22 2001 3261 3272
37. J. Kim, and A. Chauhan Dexamethasone transport and ocular delivery from poly(hydroxyethyl methacrylate) gels Int. J. Pharm. 353 2008 205 222
38. F. Fraunfelder, and S.M. Meyer Systemic adverse reactions to glaucoma medications Int. Ophthalmol. Clin. 29 1989 143 146
39. F. Fraunfelder, and S.M. Meyer Systemic side effects from ophthalmic timolol and their prevention J. Ocul. Pharmacol. Ther. 3 1987 177 184
40. A. Bobik, G. Jennings, P. Ashley, and P. Korner Timolol pharmacokinetics and effects on heart rate and blood pressure after acute and chronic administration Eur. J. Clin. Pharmacol. 16 1979 243 249
41. D. Tocco, A. Duncan, F. Deluna, H. Hucker, V. Gruber, and W. Vandenheuvel Physiological disposition and metabolism of timolol in man and laboratory animals Drug Metab. Dispos. 3 1975 361 370
42. R. Lewis, M. Lennard, P. Jackson, G. Tucker, L. Ramsay, and H. Woods Timolol and atenolol: relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics Brit. J. Clin. Pharmacol. 19 1985 329 333
43. K. Schmitz, P. Banditt, M. Motschmann, F.P. Meyer, and W. Behrens-Baumann Population pharmacokinetics of 2% topical dorzolamide in the aqueous humor of humans Invest. Ophth. Vis. Sci. 40 1999 1621 1624
44. T.O. McDonald, J.A. Shadduck, F.N. Marzulli, and H.I. Maibach Eye Irritation in Dermatotoxicology and Pharmacology 1977 John Wiley and Sons Washington, DC
45. N. Orzalesi, L. Rossetti, T. Invernizzi, A. Bottoli, and A. Autelitano Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension Invest. Ophthalmol. Vis. Sci. 41 2000 2566 2573
46. C.L. Schultz, T.R. Poling, and J.O. Mint A medical device/drug delivery system for treatment of glaucoma Clin. Exp. Optom. 92 2009 343 348
47. J. Hillman, J. Marsters, and A. Broad Pilocarpine delivery by hydrophilic lens in the management of acute glaucoma Trans. Ophthal. Soc. UK 95 1975 79 84
48. J.S. Hillman Management of acute glaucoma with pilocarpine-soaked hydrophilic lens Br. J. Ophthalmol. 58 1974 674 679
49. M. Jain Drug delivery through soft contact lenses Br. J. Ophthalmol. 72 1988 150 154
50. C.V. Leier, N.D. Baker, and P.A. Weber Cardiovascular effects of ophthalmic timolol Ann. Intern. Med. 104 1986 197 199
51. K. Dickstein, R. HaPnes, and T. Aarsland Comparison of aqueous and gellan ophthalmic timolol with placebo on the 24-hour heart rate response in patients on treatment for glaucoma Am. J. Ophthalmol. 132 2001 626 632
52. A. Alm, and J. Stjernschantz Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning: a comparison with timolol Ophthalmology 102 1995 1743 1752
53. D. Wilkie, and C. Latimer Effects of topical administration of timolol maleate on intraocular pressure and pupil size in dogs Am. J. Vet. Res. 52 1991 432 435
54. T.J. Zimmerman, and H.E. Kaufman Timolol: dose response and duration of action Arch. Ophthalmol. 95 1977 605 607
55. T.J. Zimmerman, and H.E. Kaufman Timolol: a β-adrenergic blocking agent for the treatment of glaucoma Arch. Ophthalmol. 95 1977 601 604
56. C. Gupta, A. Chauhan, and S.P. Srinivas Penetration of fluorescein across the rabbit cornea from the endothelial surface Pharm. Res. 29 2012 3325 3334
57. I. Ahmed, and T. Patton Importance of the noncorneal absorption route in topical ophthalmic drug delivery Invest. Ophthalmol. Vis. Sci. 26 1985 584 587
58. W.E. Sponsel, S. Terry, H.D. Khuu, K.-W. Lam, and H. Frenzel Periocular accumulation of timolol and betaxolol in glaucoma patients under long-term therapy Surv. Ophthalmol. 43 1999 S210 S213
59. M.F. Sugrue Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors Prog. Retin. Eye Res. 19 2000 87 112