Extended release of dexamethasone from silicone-hydrogel contact lenses containing vitamin E

Journal of Controlled Release

Volumn 148, Issue 1, 2010, Pages 110-116

  Kim, Jinah ^a   Peng, Cheng Chun ^a   Chauhan, Anuj ^a  

^a University of Florida   (United States)

Author keywords

Barriers; Contact lens; Dexamethasone; Drug delivery; Extended release; Model; Silicone hydrogel; Vitamin E

Indexed keywords

BARRIERS; DEXAMETHASONES; EXTENDED RELEASE; SILICONE HYDROGEL; VITAMIN E;

CONTACT LENSES; DRUG DELIVERY; ETHANOL; HYDROGELS; LOADING; MATHEMATICAL MODELS; SILICONES;

OPTICAL INSTRUMENTS;

ALCOHOL; ALPHA TOCOPHEROL; DEXAMETHASONE; SILICONE;

ARTICLE; CONTACT LENS; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TRANSPORT; HYDROGEL; MATHEMATICAL MODEL; PRIORITY JOURNAL;

CONTACT LENSES, EXTENDED-WEAR; DELAYED-ACTION PREPARATIONS; DEXAMETHASONE; HYDROGEL; SILICONES; VITAMIN E;

EID: 78649529312     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.119     Document Type: Article

References (20)

1. McNamara N.A., Poise K.A., Brand R.J., Graham A.D., Chan J.S., McKenney C.D. Tear mixing under a soft contact lens: effects of lens diameter. Am. J. Ophthalmol. 1999, 127:659-665.
2. Creech J.L., Chauhan A., Radke C.J. Dispersive mixing in the posterior tear film under a soft contact lens. Ind. Eng. Chem. Res. 2001, 40:3015-3026.
3. Li C.-C., Chauhan A. Modeling ophthalmic drug delivery by soaked contact lenses. Ind. Eng. Chem. Res. 2006, 45:3718-3734.
4. Le Bourlais C., Acar L., Zia H., Sado P.A., Needham T., Leverage R. Ophthalmic drug delivery systems - recent advances. Prog. Retin. Eye Res. 1998, 17:33-58.
5. Lang J.C. Ocular drug delivery conventional ocular formulations. Adv. Drug Deliv. Rev. 1995, 16:39-43.
6. Segal P. Pumps and timed release October 1991, FDA Consumer magazine.
7. Karlgard C.C.S., Wong N.S., Jones L.W., Moresoli C. In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials. Int. J. Pharm. 2003, 257:141-151.
8. Gulsen D., Chauhan A. Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle. Int. J. Pharm. 2005, 292:95-117.
9. Gulsen D., Li C.-C., Chauhan A. Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery. Curr. Eye Res. 2005, 30:1071-1080.
10. Kapoor Y., Chauhan A. Ophthalmic delivery of Cyclosporine A from Brij-97 microemulsion and surfactant-laden p-HEMA hydrogels. Int. J. Pharm. 2008, 361:222-229.
11. Kapoor Y., Chauhan A. Drug and surfactant transport in Cyclosporine A and Brij 98 laden p-HEMA hydrogels. J. Colloid Interface Sci. 2008, 322:624-633.
12. Venkatesh S., Sizemore S.P., Byrne M.E. Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics. Biomaterials 2007, 28(28):717-724.
13. Venkatesh S., Saha J., Pass S., Byrne M.E. Transport and structural analysis of molecular imprinted hydrogels for controlled drug delivery. Eur. J. Pharm. Biopharm. 2008, 69:852-860.
14. Hiratani H., Alvarez-Lorenzo C. The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems. Biomaterials 2004, 25:1105-1113.
15. Hiratani H., Mizutani Y., Alvarez-Lorenzo C. Controlling drug release from imprinted hydrogels by modifying the characteristics of the imprinted cavities. Macromol. Biosci. 2005, 5:728-733.
16. Alvarez-Lorenzo C., Hiratani H., Gomez-Amoza J.L., Martinez-Pacheco R., Souto C., Concheiro A. Soft contact lenses capable of sustained delivery of timolol. J. Pharm. Sci. 2002, 91:2182-2192.
17. Hiratani H., Alvarez-Lorenzo C. Timolol uptake and release by imprinted soft contact lenses made of N, N-diethylacrylamide and methacrylic acid. J. Control. Release 2002, 83:223-230.
18. Kim J., Conway A., Chauhan A. Extended delivery of ophthalmic drugs by silicone hydrogel contact lenses. Biomaterials 2008, 29:2259-2269.
19. Peng C.-C., Kim J., Chauhan A. Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing Vitamin E diffusion barriers. Biomaterials 2010, 31:4032-4047.
20. Melby J.C. Systemic corticosteroid therapy: pharmacology and endocrinology considerations. Ann. Intern. Med. 1974, 81:505-512.