Comparison of aqueous and gellan ophthalmic timolol with placebo on the 24-hour heart rate response in patients on treatment for glaucoma

American Journal of Ophthalmology

Volumn 132, Issue 5, 2001, Pages 626-632

  Dickstein, Kenneth ^a   Hapnes, Rune ^a   Aarsland, Torbjørn ^b  

^a STAVANGER UNIVERSITY HOSPITAL   (Norway)

^b Hjertelaget Research Foundation   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

GELLAN; PLACEBO; TIMOLOL;

ADULT; AGED; ARTICLE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; EXERCISE; FEMALE; GLAUCOMA; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HUMAN; INTRAOCULAR HYPERTENSION; MALE; PRIORITY JOURNAL;

ADRENERGIC BETA-ANTAGONISTS; CIRCADIAN RHYTHM; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; GELS; GLAUCOMA, OPEN-ANGLE; HEART RATE; HUMANS; INTRAOCULAR PRESSURE; MALE; MIDDLE AGED; OCULAR HYPERTENSION; OPHTHALMIC SOLUTIONS; SAFETY; TIMOLOL;

EID: 0034761016     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(01)01181-3     Document Type: Article

References (17)

1. Glaucoma medications, glaucoma therapy, and the evolving paradigm
2. Cardiovascular effects of ophthalmic timolol
3. Adverse respiratory and cardiovascular events attributed to timolol ophthalmic solution
4. Systemic absorption of topically applied ocular timolol
5. Relation of stroke volume during submaximal and maximal upright exercise in normal men
6. Comparison of the effect of ophthalmic timolol solution and ophthalmic timolol gel on peak exercise performance in middle-aged men
7. Effects of selective and nonselective beta-adrenergic blockade on mechanisms of exercise conditioning
8. Role of the Frank-Starling mechanism in maintaining cardiac output during increasing levels of treadmill exercise in beta-blocked normal men
9. Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade
10. Effect of nonselective β-blockade on cardiopulmonary exercise performance in men following myocardial infarction
11. A comparison of timolol versus betaxolol ophthalmic on cardiopulmonary exercise performance in healthy volunteers
12. Effect of topical timolol maleate on exercise performance
13. β-blocking effects of timolol at low plasma concentrations
14. Potential side effects of timolol therapy in the treatment of glaucoma
15. Cardiovascular effects of topical beta-blockers during exercise
16. A double-masked, placebo-controlled evaluation of timolol in a gel vehicle
17. The intraocular pressure lowering of timolol in gel-forming solution