A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide

Ophthalmology

Volumn 105, Issue 10, 1998, Pages 1952-1959

  Clineschmidt, Coleen M ^a   Williams, Robert D ^b   Snyder, Ellen ^a   Adamsons, Ingrid A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Taustine Eye Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; TIMOLOL; TIMOLOL MALEATE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EYE IRRITATION; FEMALE; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; OPEN ANGLE GLAUCOMA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME;

EID: 0031795381     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-6420(98)91047-8     Document Type: Article

References (13)

1. Kass MA, Meltzer DW, Gordon M, et al. Compliance with topical pilocarpine treatment. Am J Ophthalmol 1986;101: 515-23.
2. Eisen SA, Miller DK, Woodward RS, et al. The effect of prescribed daily dose frequency on patient medication compliance. Arch Intern Med 1990;150:1881-4.
3. Bigger JF. A comparison of patient compliance in treated vs untreated ocular hypertension. Trans Am Acad Ophthalmol Otolaryngol 1976;81:277-85.
4. Barlett JD, Fingeret M. Medical management of the glaucomas. In: Bartlett JD, Jaanus SD, eds. Clinical Ocular Pharmacology, 3rd ed. Newton, MA: Butterworth-Heinemann, 1995; chap. 35.
5. Strahlman ER, Vogel R, Tipping R, et al. The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. Ophthalmology 1996;103:1283-93.
6. McCannel CA, Heinrich SR, Brubaker RF. Acetazolamide but not timolol lowers aqueous humor flow in sleeping humans. Graefes Arch Clin Exp Ophthalmol 1992;230: 518-20.
7. Laibovitz R, Boyle J, Snyder E, et al. Dorzolamide versus pilocarpine as adjunctive therapies to timolol: a comparison of patient preference and impact on daily life. Clin Ther 1996; 18:821-32.
8. Söderström M, Wallin Ö, Granström P-A, Thorburn W. Timolol-pilocarpine combined vs timolol and pilocarpine given separately. Am J Ophthalmol 1989;107:465-70.
9. Thorburn W. Comparison of timolol and pilocarpine combination versus concomitant therapy with separate components: a Swedish multicenter study. Chibret Int J Ophthalmol 1990; 7:50-3.
10. Strahlman E, Tipping R, Vogel R, et al. A double-masked, randomized 1-year study comparing dorzolamide (TRUSOPT), timolol and betaxolol. Arch Ophthalmol 1995;113:1009-16.
11. Cramer JA, Russell ML. Strategies to enhance adherence to a medical regimen. Epilepsy Res Suppl 1988;1:163-75.
12. Cramer JA. Optimizing long-term patient compliance. Neurology 1995;45(Suppl 1):S25-8.
13. Adamsons I, Clineschmidt C, Polis A, et al. The efficacy and safety of dorzolamide as adjunctive therapy to timolol maleate gellan solution in patients with elevated intraocular pressure. J Glaucoma 1998;7:253-60.