Carrier-mediated cocaine transport at the blood-brain barrier as a putative mechanism in addiction liability

International Journal of Neuropsychopharmacology

Volumn 18, Issue 1, 2015, Pages

  Chapy, Hélène ^a,b   Smirnova, Maria ^a,b   André, Pascal ^a,b   Schlatter, Joël ^c   Chiadmi, Fouad ^c   Couraud, Pierre Olivier ^b,d,e   Scherrmann, Jean Michel ^a,b   Declèves, Xavier ^a,b   Cisternino, Salvatore ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d INSTITUT COCHIN   (France)

^e CNRS   (France)

Author keywords

Biological transport; Blood brain barrier; Cocaine; Drug of abuse; Pharmacokinetics

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYPYROVALERONE; ANTIPORTER; BENZOYLECGONINE; CARRIER PROTEIN; CATHINONE; CLONIDINE; COCAINE; DIAMORPHINE; DIPHENHYDRAMINE; HOMOCOCAINE; NICOTINE; NORCOCAINE; PROTON; PYROVALERONE; TRAMADOL; UNCLASSIFIED DRUG; DOPAMINE UPTAKE INHIBITOR; ORGANIC CATION TRANSPORTER; ORGANIC CATION TRANSPORTER 1; SLC22A2 PROTEIN, MOUSE;

ACIDIFICATION; ACTIVE TRANSPORT; ALKALINIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN PERFUSION; COCAINE DEPENDENCE; CONTROLLED STUDY; DIFFUSION FLUX; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MICHAELIS MENTEN KINETICS; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; ANIMAL; BRAIN; C57BL MOUSE; CELL LINE; DBA MOUSE; DIFFUSION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CARRIER PROTEINS; CELL LINE; COCAINE; COCAINE-RELATED DISORDERS; DIFFUSION; DOPAMINE UPTAKE INHIBITORS; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1;

EID: 84934922906     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu001     Document Type: Article

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