Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Scientific Reports

Volumn 5, Issue , 2015, Pages

  House, Carrie D ^a,d   Wang, Bi Dar ^a   Ceniccola, Kristin ^a   Williams, Russell ^a   Simaan, May ^b   Olender, Jacqueline ^a   Patel, Vyomesh ^b   Baptista Hon, Daniel T ^c   Annunziata, Christina M ^d   Gutkind, J Silvio ^b   Hales, Tim G ^c   Lee, Norman H ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; SCN5A PROTEIN, HUMAN; SMALL INTERFERING RNA; SODIUM CHANNEL NAV1.5; TELOMERE BINDING PROTEIN; TERF2IP PROTEIN, HUMAN; VERATRIDINE;

COLON TUMOR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; ION TRANSPORT; METABOLISM; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

CELL LINE, TUMOR; COLONIC NEOPLASMS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ION TRANSPORT; MAP KINASE SIGNALING SYSTEM; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; NEOPLASM INVASIVENESS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TELOMERE-BINDING PROTEINS; TRANSCRIPTION, GENETIC; VERATRIDINE;

EID: 84934908651     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep11541     Document Type: Article

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