Functional expression of the voltage-gated Na+-channel Nav1.7 is necessary for EGF-Mediated invasion in human non-Small cell lung cancer cells

Journal of Cell Science

Volumn 126, Issue 21, 2013, Pages 4939-4949

  Campbell, Thomas M ^a   Main, Martin J ^b   Fitzgerald, Elizabeth M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Epidermal growth factor receptor; Invasion; Ion channel; Metastasis; NSCLC; Voltage gated sodium channel

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA; SODIUM CHANNEL NAV1.7; TETRODOTOXIN;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER TISSUE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR BIOPSY; TUMOR INVASION; UPREGULATION;

EPIDERMAL GROWTH FACTOR RECEPTOR; INVASION; ION CHANNEL; METASTASIS; NSCLC; VOLTAGE-GATED SODIUM CHANNEL;

CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; NAV1.7 VOLTAGE-GATED SODIUM CHANNEL; NEOPLASM INVASIVENESS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84887581428     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.130013     Document Type: Article

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