Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Driffort, Virginie ^a   Gillet, Ludovic ^a   Bon, Emeline ^a   Marionneau Lambot, Séverine ^b   Oullier, Thibauld ^b   Joulin, Virginie ^c   Collin, Christine ^d   Pagès, Jean Christophe ^a,d   Jourdan, Marie Lise ^a,d   Chevalier, Stéphan ^a   Bougnoux, Philippe ^a,d   Le Guennec, Jean Yves ^e   Besson, Pierre ^a   Roger, Sébastien ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b Canceropole du Grand Ouest Plateforme Vivo   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d UNIVERSITY HOSPITAL OF TOURS   (France)

^e UNIVERSITY OF MONTPELLIER   (France)

Author keywords

Cancer cell invasiveness; Metastases; NaV1.5 voltage gated sodium channels; Ranolazine

Indexed keywords

RANOLAZINE; SODIUM CHANNEL NAV1.5; ACETANILIDE DERIVATIVE; PIPERAZINE DERIVATIVE; SCN5A PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CELL INVASION; CELL VIABILITY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; IN VITRO STUDY; IN VIVO STUDY; KRUSKAL WALLIS TEST; LUNG CANCER; LUNG METASTASIS; MOUSE; NONHUMAN; PROTEIN DEGRADATION; ANIMAL; BREAST NEOPLASMS; CELL MOTION; DRUG EFFECTS; FEMALE; HUMAN; LUNG; METABOLISM; NEOPLASM METASTASIS; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

MUS;

ACETANILIDES; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; LUNG; MICE; MICE, NUDE; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PIPERAZINES; RANOLAZINE;

EID: 84924357825     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-264     Document Type: Article

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