Lidocaine preferentially inhibits the function of purinergic P2X7 receptors expressed in Xenopus oocytes

Anesthesia and Analgesia

Volumn 120, Issue 3, 2015, Pages 597-605

  Okura, Dan ^a   Horishita, Takafumi ^a   Ueno, Susumu ^b   Yanagihara, Nobuyuki ^a   Sudo, Yuka ^c   Uezono, Yasuhito ^d   Minami, Tomoko ^a   Kawasaki, Takashi ^a   Sata, Takeyoshi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BENZOCAINE; BUPIVACAINE; LIDOCAINE; LIDOCAINE ETHOBROMIDE; MEPIVACAINE; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; ROPIVACAINE; VOLTAGE GATED SODIUM CHANNEL; LOCAL ANESTHETIC AGENT; P2RX3 PROTEIN, HUMAN; P2RX4 PROTEIN, HUMAN; P2RX7 PROTEIN, HUMAN; PURINERGIC P2X RECEPTOR ANTAGONIST;

ANALGESIC ACTIVITY; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; IC50; LOCAL ANESTHESIA; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; XENOPUS; ANIMAL; BINDING COMPETITION; BINDING SITE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; HUMAN; MEMBRANE POTENTIAL; METABOLISM; TIME; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATE; ANESTHETICS, LOCAL; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LIDOCAINE; MEMBRANE POTENTIALS; PURINERGIC P2X RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X3; RECEPTORS, PURINERGIC P2X4; RECEPTORS, PURINERGIC P2X7; TIME FACTORS; XENOPUS LAEVIS;

EID: 84927687902     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0000000000000585     Document Type: Article

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