Salivary thromboxane A2-binding proteins from triatomine vectors of chagas disease inhibit platelet-mediated neutrophil extracellular traps (NETs) formation and arterial thrombosis

PLoS Neglected Tropical Diseases

Volumn 9, Issue 6, 2015, Pages

  Mizurini, Daniella M ^a   Aslan, Jorgeane S ^a   Gomes, Tainá ^a   Ma, Dongying ^b   Francischetti, Ivo M B ^b,c   Monteiro, Robson Q ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ANTICOAGULANT AGENT; ANTINEOPLASTIC METAL COMPLEX; COLLAGEN; DIPETALODIPIN; THROMBOXANE A2; TRIPLATIN; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; ARTHROPOD PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN; SALIVA PROTEIN;

ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BLEEDING; BLOOD CLOTTING TIME; CAROTID ARTERY OBSTRUCTION; CHAGAS DISEASE; CONTROLLED STUDY; EXPERIMENTAL TEST; EXTRACELLULAR TRAP; FEMALE; HUMAN; IMMUNOFLUORESCENCE TEST; LUNG EMBOLISM; MALE; MOUSE; NEUTROPHIL; NONHUMAN; TAIL BLEEDING ASSAY; THROMBOCYTE; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; THROMBUS; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; INSECT VECTOR; METABOLISM; PHYSIOLOGY; THROMBOCYTE AGGREGATION; THROMBOSIS; TRANSMISSION; TRIATOMINAE;

ANIMALS; ARTHROPOD PROTEINS; BLOOD PLATELETS; CHAGAS DISEASE; EXTRACELLULAR TRAPS; FEMALE; HUMANS; INSECT VECTORS; MALE; MICE; MICE, INBRED BALB C; NEUTROPHILS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; RECOMBINANT PROTEINS; SALIVARY PROTEINS AND PEPTIDES; THROMBOSIS; THROMBOXANE A2; TRIATOMINAE;

EID: 84934784179     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003869     Document Type: Article

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