Purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus

Journal of Biological Chemistry

Volumn 275, Issue 17, 2000, Pages 12639-12650

  Francischetti, Ivo M B ^a   Ribeiro, José M C ^a,d   Champagne, Donald ^b   Andersen, John ^c  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c University of Arizona   (United States)

^d MSC 0425 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; COLLAGEN; COMPLEMENTARY DNA; GLYCOPROTEIN; INDOMETACIN; INTEGRIN; LIPOCALIN; THROMBIN; THROMBOXANE A2 RECEPTOR STIMULATING AGENT;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DNA LIBRARY; DNA SEQUENCE; EXPRESSION VECTOR; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RHODNIUS; SALIVARY GLAND; SEQUENCE HOMOLOGY; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA; THROMBOCYTE SHAPE;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; BLOOD PLATELETS; CALCIUM; CATTLE; CELL ADHESION; CELL AGGREGATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CLONING, MOLECULAR; COLLAGEN; CROTALID VENOMS; CYCLIC AMP; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INSECT PROTEINS; LECTINS, C-TYPE; MOLECULAR SEQUENCE DATA; PLATELET AGGREGATION INHIBITORS; RABBITS; RHODNIUS; SALIVARY GLANDS; SALIVARY PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; THROMBOXANE A2; TIME FACTORS; TRYPTOPHAN;

ANIMALIA; ESCHERICHIA COLI; HEXAPODA; RHODNIUS PROLIXUS; TRIATOMA PALLIDIPENNIS;

EID: 0034724672     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.17.12639     Document Type: Article

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