Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of chagas disease, binds to TXA2 but does not interact with glycoprotein PVI

Thrombosis and Haemostasis

Volumn 107, Issue 1, 2012, Pages 111-123

  Ma, Dongying ^a   Assumpção, Teresa C F ^a   Li, Yuan ^a   Andersen, John F ^a   Ribeiro, José M C ^a   Francischetti, Ivo M B ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Platelet physiology; Protein function activity; Snake venoms

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; APOLIPOPROTEIN D; ARACHIDONIC ACID; BIOGENIC AMINE; COLLAGEN; CONVULXIN; DIPETALODIPIN; GLYCOPROTEIN VI; LEUKOTRIENE; LIPOCALIN; PALLIDIPIN; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN J2; THROMBOXANE A2; THROMBOXANE B2; TRIABIN; TRIPLATIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SPECIFICITY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION INHIBITION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; AMINES; ANIMALS; ARACHIDONIC ACID; HORSES; HUMANS; LIGANDS; MODELS, BIOLOGICAL; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; PROSTAGLANDINS H; PROTEIN BINDING; SALIVARY GLANDS; SALIVARY PROTEINS AND PEPTIDES; SNAKES; THROMBOXANE A2;

EID: 84855313457     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH11-10-0685     Document Type: Article

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