메뉴 건너뛰기




Volumn 948, Issue , 2013, Pages 105-120

Synthesis of polyethylenimine-based nanocarriers for systemic tumor targeting of nucleic acids

Author keywords

EGF receptor; Gene delivery; Molecular conjugates; Polyethylene glycol; Polyethylenimine; Targeting

Indexed keywords

LIGAND; NUCLEIC ACID; PEPTIDE; PLASMID DNA; POLYETHYLENEIMINE; RNA;

EID: 84934442996     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-140-0_8     Document Type: Article
Times cited : (15)

References (35)
  • 2
    • 0030775528 scopus 로고    scopus 로고
    • The in fluence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
    • Tang MX, Szoka FC (1997) The in fluence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 4:823-832
    • (1997) Gene Ther , vol.4 , pp. 823-832
    • Tang, M.X.1    Szoka, F.C.2
  • 3
    • 3042857264 scopus 로고    scopus 로고
    • A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
    • Kopatz I, Remy JS, Behr JP (2004) A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin. J Gene Med 6:769-776
    • (2004) J Gene Med , vol.6 , pp. 769-776
    • Kopatz, I.1    Remy, J.S.2    Behr, J.P.3
  • 4
    • 0242414440 scopus 로고    scopus 로고
    • Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
    • Sonawane ND, Szoka FC Jr, Verkman AS (2003) Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem 278:44826-44831
    • (2003) J Biol Chem , vol.278 , pp. 44826-44831
    • Sonawane, N.D.1    Szoka Jr., F.C.2    Verkman, A.S.3
  • 5
    • 0030729180 scopus 로고    scopus 로고
    • ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo
    • Ferrari S, Moro E, Pettenazzo A, Behr JP, Zacchello F, Scarpa M (1997) ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo. Gene Ther 4:1100-1106
    • (1997) Gene Ther , vol.4 , pp. 1100-1106
    • Ferrari, S.1    Moro, E.2    Pettenazzo, A.3    Behr, J.P.4    Zacchello, F.5    Scarpa, M.6
  • 7
    • 0035408714 scopus 로고    scopus 로고
    • Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
    • Wightman L, Kircheis R, Rossler V, Carotta S, Ruzicka R, Kursa M, Wagner E (2001) Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med 3:362-372
    • (2001) J Gene Med , vol.3 , pp. 362-372
    • Wightman, L.1    Kircheis, R.2    Rossler, V.3    Carotta, S.4    Ruzicka, R.5    Kursa, M.6    Wagner, E.7
  • 9
    • 70449110501 scopus 로고    scopus 로고
    • Friedmann T, Rossi J (eds Gene transfer: delivery and expression of DNA and RNA, a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Ogris M, Wagner E (2008) Linear polyethylenimine: synthesis and transfection procedures for in vitro and in vivo. In: Friedmann T, Rossi J (eds) Gene transfer: delivery and expression of DNA and RNA, a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 521-526
    • (2008) Linear Polyethylenimine: Synthesis and Transfection Procedures for in Vitro and in Vivo , pp. 521-526
    • Ogris, M.1    Wagner, E.2
  • 10
    • 17644418754 scopus 로고    scopus 로고
    • Full deacylation of polyethylenimine dramatically boosts its gene delivery ef fi ciency and speci fi city to mouse lung
    • Thomas M, Lu JJ, Ge Q, Zhang C, Chen J, Klibanov AM (2005) Full deacylation of polyethylenimine dramatically boosts its gene delivery ef fi ciency and speci fi city to mouse lung. Proc Natl Acad Sci U S A 102:5679-5684
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5679-5684
    • Thomas, M.1    Lu, J.J.2    Ge, Q.3    Zhang, C.4    Chen, J.5    Klibanov, A.M.6
  • 11
    • 11844290850 scopus 로고    scopus 로고
    • Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
    • Boeckle S, von Gersdorff K, van der Piepen S, Culmsee C, Wagner E, Ogris M (2004) Puri fi cation of polyethylenimine polyplexes highlights the role of free polycations in gene transfer. J Gene Med 6:1102-1111
    • (2004) J Gene Med , vol.6 , pp. 1102-1111
    • Boeckle, S.1    Von Gersdorff, K.2    Van Der Piepen, S.3    Culmsee, C.4    Wagner, E.5    Ogris, M.6
  • 13
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet P, Favrot MC, Hurbin A, Coll JL (2002) Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J Gene Med 4:84-91
    • (2002) J Gene Med , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3    Coll, J.L.4
  • 14
    • 3242707528 scopus 로고    scopus 로고
    • Situ single cell observation by fl uorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine
    • Itaka K, Harada A, Yamasaki Y, Nakamura K, Kawaguchi H, Kataoka K (2004) In situ single cell observation by fl uorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine. J Gene Med 6:76-84
    • (2004) J Gene Med , vol.6 , pp. 76-84
    • Itaka, K.1    Harada, A.2    Yamasaki, Y.3    Nakamura, K.4    Kawaguchi, H.5    Kataoka, K.6
  • 16
    • 70449096070 scopus 로고    scopus 로고
    • Drug nanocarriers labeled with near-infraredemitting quantum dots (quantoplexes): Imaging fast dynamics of distribution in living animals
    • Zintchenko A, Susha AS, Concia M, Feldmann J, Wagner E, Rogach AL, Ogris M (2009) Drug nanocarriers labeled with near-infraredemitting quantum dots (quantoplexes): imaging fast dynamics of distribution in living animals. Mol Ther 17:1849-1856
    • (2009) Mol Ther , vol.17 , pp. 1849-1856
    • Zintchenko, A.1    Susha, A.S.2    Concia, M.3    Feldmann, J.4    Wagner, E.5    Rogach, A.L.6    Ogris, M.7
  • 17
    • 0142072936 scopus 로고    scopus 로고
    • Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-Targeted gene transfer
    • Kursa M, Walker GF, Roessler V, Ogris M, Roedl W, Kircheis R, Wagner E (2003) Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-Targeted gene transfer. Bioconjug Chem 14:222-231
    • (2003) Bioconjug Chem , vol.14 , pp. 222-231
    • Kursa, M.1    Walker, G.F.2    Roessler, V.3    Ogris, M.4    Roedl, W.5    Kircheis, R.6    Wagner, E.7
  • 18
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin- PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schuller S, Kircheis R, Wagner E (1999) PEGylated DNA/transferrin- PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 6:595-605
    • (1999) Gene Ther , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 21
    • 47249130263 scopus 로고    scopus 로고
    • Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
    • Fella C, Walker GF, Ogris M, Wagner E (2008) Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding. Eur J Pharm Sci 34:309-320
    • (2008) Eur J Pharm Sci , vol.34 , pp. 309-320
    • Fella, C.1    Walker, G.F.2    Ogris, M.3    Wagner, E.4
  • 22
    • 14044252938 scopus 로고    scopus 로고
    • Toward synthetic viruses: Endosomal pH-Triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo
    • Walker GF, Fella C, Pelisek J, Fahrmeir J, Boeckle S, Ogris M, Wagner E (2005) Toward synthetic viruses: endosomal pH-Triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol Ther 11:418-425
    • (2005) Mol Ther , vol.11 , pp. 418-425
    • Walker, G.F.1    Fella, C.2    Pelisek, J.3    Fahrmeir, J.4    Boeckle, S.5    Ogris, M.6    Wagner, E.7
  • 24
    • 0035131596 scopus 로고    scopus 로고
    • Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
    • Kircheis R, Wightman L, Schreiber A, Robitza B, Rossler V, Kursa M, Wagner E (2001) Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 8:28-40
    • (2001) Gene Ther , vol.8 , pp. 28-40
    • Kircheis, R.1    Wightman, L.2    Schreiber, A.3    Robitza, B.4    Rossler, V.5    Kursa, M.6    Wagner, E.7
  • 25
    • 18044400296 scopus 로고    scopus 로고
    • DNA/polyethylenimine transfection particles in fluence of ligands, polymer size, and PEGylation on internalization and gene expression
    • Ogris M, Steinlein P, Carotta S, Brunner S, Wagner E (2001) DNA/polyethylenimine transfection particles: In fluence of ligands, polymer size, and PEGylation on internalization and gene expression. AAPS Pharm Sci 3:E21
    • (2001) AAPS Pharm Sci , vol.3 , pp. 21
    • Ogris, M.1    Steinlein, P.2    Carotta, S.3    Brunner, S.4    Wagner, E.5
  • 26
    • 0141990620 scopus 로고    scopus 로고
    • Tumor-Targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes
    • Ogris M, Walker G, Blessing T, Kircheis R, Wolschek M, Wagner E (2003) Tumor-Targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes. J Control Release 91:173-181
    • (2003) J Control Release , vol.91 , pp. 173-181
    • Ogris, M.1    Walker, G.2    Blessing, T.3    Kircheis, R.4    Wolschek, M.5    Wagner, E.6
  • 27
    • 79960368490 scopus 로고    scopus 로고
    • Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR) mediated delivery: A fully synthetic, EGFR-Targeted gene transfer system avoiding receptor activation
    • Schafer A, Pahnke A, Schaffert D, Van Weerden WM, de Ridder CM, Rodl W, Vetter A, Spitzweg C, Kraaij R, Wagner E, Ogris M (2011) Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR) mediated delivery: a fully synthetic, EGFR-Targeted gene transfer system avoiding receptor activation. Hum Gene Ther 22:1463-1473
    • (2011) Hum Gene Ther , vol.22 , pp. 1463-1473
    • Schafer, A.1    Pahnke, A.2    Schaffert, D.3    Van Weerden, W.M.4    De Ridder, C.M.5    Rodl, W.6    Vetter, A.7    Spitzweg, C.8    Kraaij, R.9    Wagner, E.10    Ogris, M.11
  • 28
    • 55549102623 scopus 로고    scopus 로고
    • Phase I/II marker lesion study of intravesical BC-819 DNA plasmid in H19 over expressing super fi cial bladder cancer refractory to bacillus calmette-guerin
    • Sidi AA, Ohana P, Benjamin S, Shalev M, Ransom JH, Lamm D, Hochberg A, Leibovitch I (2008) Phase I/II marker lesion study of intravesical BC-819 DNA plasmid in H19 over expressing super fi cial bladder cancer refractory to bacillus calmette-guerin. J Urol 180: 2379-2383
    • (2008) J Urol , vol.180 , pp. 2379-2383
    • Sidi, A.A.1    Ohana, P.2    Benjamin, S.3    Shalev, M.4    Ransom, J.H.5    Lamm, D.6    Hochberg, A.7    Leibovitch, I.8
  • 29
    • 0037419724 scopus 로고    scopus 로고
    • Spectrophotometric determination of polyethylenimine in the presence of an oligonucleotide for the characterization of controlled release formulations
    • Ungaro F, De Rosa G, Miro A, Quaglia F (2003) Spectrophotometric determination of polyethylenimine in the presence of an oligonucleotide for the characterization of controlled release formulations. J Pharm Biomed Anal 31:143-149
    • (2003) J Pharm Biomed Anal , vol.31 , pp. 143-149
    • Ungaro, F.1    De Rosa, G.2    Miro, A.3    Quaglia, F.4
  • 31
    • 0035850217 scopus 로고    scopus 로고
    • DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline
    • Jeong JH, Song SH, Lim DW, Lee H, Park TG (2001) DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline). J Control Release 73:391-399
    • (2001) J Control Release , vol.73 , pp. 391-399
    • Jeong, J.H.1    Song, S.H.2    Lim, D.W.3    Lee, H.4    Park, T.G.5
  • 32
    • 3042667834 scopus 로고    scopus 로고
    • Animal-free production of ccc-supercoiled plasmids for research and clinical applications
    • Schleef M, Schmidt T (2004) Animal-free production of ccc-supercoiled plasmids for research and clinical applications. J Gene Med 6(Suppl 1):S45-S53
    • (2004) J Gene Med , vol.6 , Issue.SUPPL. 1
    • Schleef, M.1    Schmidt, T.2
  • 33
    • 79960850563 scopus 로고    scopus 로고
    • Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations
    • Magnusson T, Haase R, Schleef M, Wagner E, Ogris M (2011) Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations. J Gene Med 13:382-391
    • (2011) J Gene Med , vol.13 , pp. 382-391
    • Magnusson, T.1    Haase, R.2    Schleef, M.3    Wagner, E.4    Ogris, M.5
  • 34
    • 78650695686 scopus 로고    scopus 로고
    • The establishment of an upscaled micro-mixer method allows the standardized and reproducible preparation of well-de fined plasmid/LPEI polyplexes
    • Kasper JC, Schaffert D, Ogris M, Wagner E, Friess W (2011) The establishment of an upscaled micro-mixer method allows the standardized and reproducible preparation of well-de fined plasmid/LPEI polyplexes. Eur J Pharm Biopharm 77:182-185
    • (2011) Eur J Pharm Biopharm , vol.77 , pp. 182-185
    • Kasper, J.C.1    Schaffert, D.2    Ogris, M.3    Wagner, E.4    Friess, W.5
  • 35
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris M, Steinlein P, Kursa M, Mechtler K, Kircheis R, Wagner E (1998) The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther 5:1425-1433
    • (1998) Gene Ther , vol.5 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.