-
1
-
-
0028288927
-
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
-
A. C. Chan, D. M. Desai and A. Weiss, The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction, Annu. Rev. Immunol. 12, 555-592 (1994).
-
(1994)
Annu. Rev. Immunol
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.M.2
Weiss, A.3
-
2
-
-
7944231534
-
Function of the Src-family kinases, Lck and Fyn, in Tcell development and activation
-
E. H. Palacios and A. Weiss, Function of the Src-family kinases, Lck and Fyn, in Tcell development and activation, Oncogene 23, 7990-8000 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7990-8000
-
-
Palacios, E.H.1
Weiss, A.2
-
3
-
-
0029347999
-
The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes
-
N. S. van Oers and A. Weiss, The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes, Semin. Immunol. 7, 227-236 (1995).
-
(1995)
Semin. Immunol
, vol.7
, pp. 227-236
-
-
van Oers, N.S.1
Weiss, A.2
-
4
-
-
17144384996
-
Tec family kinases in T lymphocyte development and function
-
L. J. Berg, L. D. Finkelstein, J. A. Lucas and P. L. Schwartzberg, Tec family kinases in T lymphocyte development and function, Annu. Rev. Immunol. 23, 549-600 (2005).
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 549-600
-
-
Berg, L.J.1
Finkelstein, L.D.2
Lucas, J.A.3
Schwartzberg, P.L.4
-
5
-
-
13344270890
-
Altered T cell receptor signaling and disrupted T cell development in mice lacking itk
-
X. C. Liao and D. R. Littman, Altered T cell receptor signaling and disrupted T cell development in mice lacking itk, Immunity 3, 757-769 (1995).
-
(1995)
Immunity
, vol.3
, pp. 757-769
-
-
Liao, X.C.1
Littman, D.R.2
-
6
-
-
0033597440
-
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity
-
E. M. Schaeffer, J. Debnath, G. Yap, D. McVicar, X. C. Liao, D. R. Littman, A. Sher, H. E. Varmus, M. J. Lenardo and P. L. Schwartzberg, Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity, Science 284, 638-641 (1999).
-
(1999)
Science
, vol.284
, pp. 638-641
-
-
Schaeffer, E.M.1
Debnath, J.2
Yap, G.3
McVicar, D.4
Liao, X.C.5
Littman, D.R.6
Sher, A.7
Varmus, H.E.8
Lenardo, M.J.9
Schwartzberg, P.L.10
-
7
-
-
0032543221
-
T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells
-
K. Q. Liu, S. C. Bunnell, C. B. Gurniak and L. J. Berg, T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells, J. Exp. Med. 187, 1721-1727 (1998).
-
(1998)
J. Exp. Med
, vol.187
, pp. 1721-1727
-
-
Liu, K.Q.1
Bunnell, S.C.2
Gurniak, C.B.3
Berg, L.J.4
-
8
-
-
0033213484
-
Impaired NFATc translocation and failure of Th2 development in Itk- deficient CD4+ T cells
-
D. J. Fowell, K. Shinkai, X. C. Liao, A. M. Beebe, R. L. Coffman, D. R. Littman and R. M. Locksley, Impaired NFATc translocation and failure of Th2 development in Itk- deficient CD4+ T cells, Immunity 11, 399-409 (1999).
-
(1999)
Immunity
, vol.11
, pp. 399-409
-
-
Fowell, D.J.1
Shinkai, K.2
Liao, X.C.3
Beebe, A.M.4
Coffman, R.L.5
Littman, D.R.6
Locksley, R.M.7
-
9
-
-
0037446773
-
Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor
-
J. A. Grasis, C. D. Browne and C. D. Tsoukas, Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor, J. Immunol. 170, 3971-3976 (2003).
-
(2003)
J. Immunol
, vol.170
, pp. 3971-3976
-
-
Grasis, J.A.1
Browne, C.D.2
Tsoukas, C.D.3
-
10
-
-
0033486066
-
Emt/Itk associates with activated TCR complexes: Role of the pleckstrin homology domain
-
K. A. Ching, Y. Kawakami, T. Kawakami and C. D. Tsoukas, Emt/Itk associates with activated TCR complexes: role of the pleckstrin homology domain, J. Immunol. 163, 6006-6013 (1999).
-
(1999)
J. Immunol
, vol.163
, pp. 6006-6013
-
-
Ching, K.A.1
Kawakami, Y.2
Kawakami, T.3
Tsoukas, C.D.4
-
11
-
-
0033190523
-
Tec family of protein-tyrosine kinases: An overview of their structure and function
-
H. Mano, Tec family of protein-tyrosine kinases: an overview of their structure and function, Cytokine Growth Factor Rev. 10, 267-280 (1999).
-
(1999)
Cytokine Growth Factor Rev
, vol.10
, pp. 267-280
-
-
Mano, H.1
-
12
-
-
0031029781
-
Regulatory intramolecular association in a tyrosine kinase of the Tec family
-
A. Andreotti, S. Bunnell, S. Feng, L. Berg and S. Schreiber, Regulatory intramolecular association in a tyrosine kinase of the Tec family, Nature 385, 93-97 (1997).
-
(1997)
Nature
, vol.385
, pp. 93-97
-
-
Andreotti, A.1
Bunnell, S.2
Feng, S.3
Berg, L.4
Schreiber, S.5
-
13
-
-
0033696009
-
Tec kinases: A family with multiple roles in immunity
-
W. C. Yang, Y. Collette, J. Nunes and D. Olive, Tec kinases: a family with multiple roles in immunity, Immunity 12, 373-382 (2000).
-
(2000)
Immunity
, vol.12
, pp. 373-382
-
-
Yang, W.C.1
Collette, Y.2
Nunes, J.3
Olive, D.4
-
14
-
-
0030292702
-
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
-
G. O. Cory, L. MacCarthy-Morrogh, S. Banin, I. Gout, P. M. Brickell, R. J. Levinsky, C. Kinnon and R. C. Lovering, Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways, J. Immunol. 157, 3791-3795 (1996).
-
(1996)
J. Immunol
, vol.157
, pp. 3791-3795
-
-
Cory, G.O.1
MacCarthy-Morrogh, L.2
Banin, S.3
Gout, I.4
Brickell, P.M.5
Levinsky, R.J.6
Kinnon, C.7
Lovering, R.C.8
-
15
-
-
0029834340
-
Identification of Itk/Tsk Src homology 3 domain ligands
-
S. Bunnell, P. Henry, R. Kolluri, T. Kirchhausen, R. Rickles and L. Berg, Identification of Itk/Tsk Src homology 3 domain ligands., J. Biol. Chem. 271, 25646-25656 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 25646-25656
-
-
Bunnell, S.1
Henry, P.2
Kolluri, R.3
Kirchhausen, T.4
Rickles, R.5
Berg, L.6
-
16
-
-
0034235114
-
TCR/CD3-induced activation and binding of Emt/Itk to LAT complexes; requirement for the SH2 domain
-
K. A. Ching, J. Grasis, P. Tailor, Y. Kawakami, T. Kawakami and C. D. Tsoukas, TCR/CD3-induced activation and binding of Emt/Itk to LAT complexes; requirement for the SH2 domain, J. Immunol. 165, 256-262 (2000).
-
(2000)
J. Immunol
, vol.165
, pp. 256-262
-
-
Ching, K.A.1
Grasis, J.2
Tailor, P.3
Kawakami, Y.4
Kawakami, T.5
Tsoukas, C.D.6
-
17
-
-
0037318720
-
Adaptors as central mediators of signal transduction in immune cells
-
M. S. Jordan, A. L. Singer and G. A. Koretzky, Adaptors as central mediators of signal transduction in immune cells, Nat. Immunol. 4, 110-116 (2003).
-
(2003)
Nat. Immunol
, vol.4
, pp. 110-116
-
-
Jordan, M.S.1
Singer, A.L.2
Koretzky, G.A.3
-
18
-
-
0036221481
-
Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins
-
L. E. Samelson, Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins, Annu. Rev. Immunol. 20, 371-394 (2002).
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 371-394
-
-
Samelson, L.E.1
-
19
-
-
0032878516
-
Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment
-
X. Shan and R. L. Wange, Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment, J. Biol. Chem. 274, 29323-29330 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 29323-29330
-
-
Shan, X.1
Wange, R.L.2
-
20
-
-
0032701019
-
Interaction of SLP adaptors with the SH2 domain of Tec family kinases
-
Y. W. Su, Y. Zhang, J. Schweikert, G. A. Koretzky, M. Reth and J. Wienands, Interaction of SLP adaptors with the SH2 domain of Tec family kinases, Eur. J. Immunol. 29, 3702-3711 (1999).
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 3702-3711
-
-
Su, Y.W.1
Zhang, Y.2
Schweikert, J.3
Koretzky, G.A.4
Reth, M.5
Wienands, J.6
-
21
-
-
0032541062
-
Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76- deficient T cell
-
D. Yablonski, M. R. Kuhne, T. Kadlecek and A. Weiss, Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76- deficient T cell, Science 281, 413-416 (1998).
-
(1998)
Science
, vol.281
, pp. 413-416
-
-
Yablonski, D.1
Kuhne, M.R.2
Kadlecek, T.3
Weiss, A.4
-
22
-
-
0033534525
-
The actin cytoskeleton and lymphocyte activation
-
J. M. Penninger and G. R. Crabtree, The actin cytoskeleton and lymphocyte activation, Cell 96, 9-12 (1999).
-
(1999)
Cell
, vol.96
, pp. 9-12
-
-
Penninger, J.M.1
Crabtree, G.R.2
-
23
-
-
0032493028
-
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
-
L. J. Holsinger, I. A. Graef, W. Swat, T. Chi, D. M. Bautista, L. Davidson, R. S. Lewis, F. W. Alt and G. R. Crabtree, Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction, Curr. Biol. 8, 563-572 (1998).
-
(1998)
Curr. Biol
, vol.8
, pp. 563-572
-
-
Holsinger, L.J.1
Graef, I.A.2
Swat, W.3
Chi, T.4
Bautista, D.M.5
Davidson, L.6
Lewis, R.S.7
Alt, F.W.8
Crabtree, G.R.9
-
24
-
-
0034232037
-
The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
-
M. L. Dustin and J. A. Cooper, The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling, Nature Immunology 1, 23-29 (2000).
-
(2000)
Nature Immunology
, vol.1
, pp. 23-29
-
-
Dustin, M.L.1
Cooper, J.A.2
-
25
-
-
0032559586
-
Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism
-
B. Lowin-Kropf, V. S. Shapiro and A. Weiss, Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism, J. Cell. Biol. 140, 861-871 (1998).
-
(1998)
J. Cell. Biol
, vol.140
, pp. 861-871
-
-
Lowin-Kropf, B.1
Shapiro, V.S.2
Weiss, A.3
-
26
-
-
0023427610
-
Effects of cytochalasin and phalloidin on actin
-
J. A. Cooper, Effects of cytochalasin and phalloidin on actin, J. Cell. Biol. 105, 1473-1478 (1987).
-
(1987)
J. Cell. Biol
, vol.105
, pp. 1473-1478
-
-
Cooper, J.A.1
-
27
-
-
19944431032
-
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton
-
D. Dombroski, R. A. Houghtling, C. M. Labno, P. Precht, A. Takesono, N. J. Caplen, D. D. Billadeau, R. L. Wange, J. K. Burkhardt and P. L. Schwartzberg, Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton, J. Immunol. 174, 1385-1392 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 1385-1392
-
-
Dombroski, D.1
Houghtling, R.A.2
Labno, C.M.3
Precht, P.4
Takesono, A.5
Caplen, N.J.6
Billadeau, D.D.7
Wange, R.L.8
Burkhardt, J.K.9
Schwartzberg, P.L.10
-
28
-
-
10744228513
-
Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP
-
C. M. Labno, C. M. Lewis, D. You, D. W. Leung, A. Takesono, N. Kamberos, A. Seth, L. D. Finkelstein, M. K. Rosen, P. L. Schwartzberg and J. K. Burkhardt, Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP, Curr. Biol. 13, 1619-1624 (2003).
-
(2003)
Curr. Biol
, vol.13
, pp. 1619-1624
-
-
Labno, C.M.1
Lewis, C.M.2
You, D.3
Leung, D.W.4
Takesono, A.5
Kamberos, N.6
Seth, A.7
Finkelstein, L.D.8
Rosen, M.K.9
Schwartzberg, P.L.10
Burkhardt, J.K.11
-
29
-
-
0030798980
-
Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity
-
S. D. Heyeck, H. M. Wilcox, S. C. Bunnell and L. J. Berg, Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity, J. Biol. Chem. 272, 25401-25408 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 25401-25408
-
-
Heyeck, S.D.1
Wilcox, H.M.2
Bunnell, S.C.3
Berg, L.J.4
-
30
-
-
0141510045
-
Itk phosphorylation sites are required for functional activity in primary T cells
-
H. M. Wilcox and L. J. Berg, Itk phosphorylation sites are required for functional activity in primary T cells, J. Biol. Chem. 278, 37112-37121 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 37112-37121
-
-
Wilcox, H.M.1
Berg, L.J.2
-
31
-
-
3142686560
-
Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet
-
A. T. Miller, H. M. Wilcox, Z. Lai and L. J. Berg, Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet, Immunity 21, 67-80 (2004).
-
(2004)
Immunity
, vol.21
, pp. 67-80
-
-
Miller, A.T.1
Wilcox, H.M.2
Lai, Z.3
Berg, L.J.4
-
32
-
-
12344269852
-
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
-
E. S. Hwang, S. J. Szabo, P. L. Schwartzberg and L. H. Glimcher, T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3, Science 307, 430-433 (2005).
-
(2005)
Science
, vol.307
, pp. 430-433
-
-
Hwang, E.S.1
Szabo, S.J.2
Schwartzberg, P.L.3
Glimcher, L.H.4
-
33
-
-
0034919058
-
Itk/Emt: A link between T cell antigen receptor-mediated Ca2+ events and cytoskeletal reorganization
-
C. D. Tsoukas, J. A. Grasis, K. A. Ching, Y. Kawakami and T. Kawakami, Itk/Emt: a link between T cell antigen receptor-mediated Ca2+ events and cytoskeletal reorganization, Trends in Immunol. 22, 17-20 (2001).
-
(2001)
Trends in Immunol
, vol.22
, pp. 17-20
-
-
Tsoukas, C.D.1
Grasis, J.A.2
Ching, K.A.3
Kawakami, Y.4
Kawakami, T.5
-
34
-
-
0034683671
-
Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex
-
H. N. Higgs and T. D. Pollard, Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex, J. Cell. Biol. 150, 1311-1320. (2000).
-
(2000)
J. Cell. Biol
, vol.150
, pp. 1311-1320
-
-
Higgs, H.N.1
Pollard, T.D.2
-
35
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
A. S. Kim, L. T. Kakalis, N. Abdul-Manan, G. A. Liu and M. K. Rosen, Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein, Nature 404, 151-158 (2000).
-
(2000)
Nature
, vol.404
, pp. 151-158
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
36
-
-
0037160142
-
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein
-
G. O. Cory, R. Garg, R. Cramer and A. J. Ridley, Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein, J. Biol. Chem. 277, 45115-45121 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 45115-45121
-
-
Cory, G.O.1
Garg, R.2
Cramer, R.3
Ridley, A.J.4
-
37
-
-
0347915637
-
Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation
-
K. Badour, J. Zhang, F. Shi, Y. Leng, M. Collins and K. A. Siminovitch, Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation, J. Exp. Med. 199, 99-112 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 99-112
-
-
Badour, K.1
Zhang, J.2
Shi, F.3
Leng, Y.4
Collins, M.5
Siminovitch, K.A.6
|