The social environment and neurogenesis in the adult mammalian brain

Frontiers in Human Neuroscience

Volumn , Issue MAY 2012, 2012, Pages

  Lieberwirth, Claudia ^a   Wang, Zuoxin ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Adult neurogenesis; Amygdala; Hippocampus; Hypothalamus; Olfactory bulb; Social behavior

Indexed keywords

PHEROMONE;

BRAIN REGION; DOMINANCE BEHAVIOR; ENVIRONMENTAL STRESS; HORMONAL REGULATION; HUMAN; MATE CHOICE; MENTAL STRESS; NERVE CELL DIFFERENTIATION; NONHUMAN; PARENTHOOD; PREDATOR STRESS; PREGNANCY; REVIEW; SIBLING RELATION; SOCIAL ENVIRONMENT; SOCIAL INTERACTION; SOCIAL ISOLATION; SOCIAL SUPPORT;

EID: 84933676666     PISSN: 16625161     EISSN: 16625161     Source Type: Journal    
DOI: 10.3389/fnhum.2012.00118     Document Type: Review

References (222)

1. Achenbach, G. G., and Snowdon, C. T. (2002). Costs of caregiving: weight loss in captive adult male cotton-top tamarins (Saguinus oedipus) following the birth of infants. Int. J. Primatol. 23, 179-189.
2. Adams, K. B., Sanders, S., and Auth, E. A. (2004). Loneliness and depression in independent living retirement communities: risk and resilience factors. Aging Ment. Health 8, 475-485.
3. Akbari, E. M., Chatterjee, D., Levy, F., and Fleming, A. S. (2007). Experience-dependent cell survival in the maternal rat brain. Behav. Neurosci. 121, 1001-1011.
4. Alpass, F. M., and Neville, S. (2003). Loneliness, health and depression in older males. Aging Ment. Health 7, 212-216.
5. Antzoulatos, E., Magorien, J. E., and Wood, R. I. (2008). Cell proliferation and survival in the mating circuit of adult male hamsters: effects of testosterone and sexual behavior. Horm. Behav. 54, 735-740.
6. Atkinson, H. C., and Waddell, B. J. (1995). The hypothalamic-pituitary-adrenal axis in rat pregnancy and lactation: circadian variation and interrelationship of plasma adrenocorticotropin and corticosterone. Endocrinology 136, 512-520.
7. Barha, C. K., Lieblich, S. E., and Galea, L. A. (2009). Different forms of oestrogen rapidly upregulate cell proliferation in the dentate gyrus of adult female rats. J. Neuroendocrinol. 21, 155-166.
8. Barker, J. M., and Galea, L. A. (2008). Repeated estradiol administration alters different aspects of neurogenesis and cell death in the hippocampus of female, but not male, rats. Neuroscience 152, 888-902.
9. Baudoin, C., Busquet, N., Dobson, F. S., Gheusi, G., Feron, C., Durand, J. L., Heth, G., Patris, B., and Todrank, J. (2005). Male-female associations and female olfactory neurogenesis with pair bonding in Mus spicilegus. Biol. J. Linn. Soc. Lond. 84, 323-334.
10. Becker, J. B., Arnold, A. P., Berkley, K. J., Blaustein, J. D., Eckel, L. A., Hampson, E., Herman, J. P., Marts, S., Sadee, W., Steiner, M., Taylor, J., and Young, E. (2005). Strategies and methods for research on sex differences in brain and behavior. Endocrinology 146, 1650-1673.
11. Bedard, A., and Parent, A. (2004). Evidence of newly generated neurons in the human olfactory bulb. Brain Res. Dev. Brain Res. 151, 159-168.
12. Bell, N. J., Forthun, L. F., and Sun, S. W. (2000). Attachment, adolescent competencies, and substance use: developmental considerations in the study of risk behaviors. Subst. Use Misuse 35, 1177-1206.
13. Bernier, P. J., Bedard, A., Vinet, J., Levesque, M., and Parent, A. (2002). Newly generated neurons in the amygdala and adjoining cortex of adult primates. Proc. Natl. Acad. Sci. U.S.A. 99, 11464-11469.
14. Brennan, P. A., and Keverne, E. B. (2004). Something in the air? New insights into mammalian pheromones. Curr. Biol. 14, R81-R89.
15. Brennan, P. A. (2010). "Pheromones and mammalian behavior," in The Neurobiology of Olfaction, ed. A. Menini (Boca Raton, FL: CRC Press), 157-180.
16. Bridges, R. S., and Bridges, R. S. (2008). Neurobiology of the Parental Brain. London: Academic Press.
17. Bronson, F. H. (1989). Mammalian Reproductive Biology. Chicago: University of Chicago Press.
18. Bruel-Jungerman, E., Laroche, S., and Rampon, C. (2005). New neurons in the dentate gyrus are involved in the expression of enhanced long-term memory following environmental enrichment. Eur. J. Neurosci. 21, 513-521.
19. Brus, M., Meurisse, M., Franceschini, I., Keller, M., and Levy, F. (2010). Evidence for cell proliferation in the sheep brain and its down-regulation by parturition and interactions with the young. Horm. Behav. 58, 737-746.
20. Bulte, J. W. M., and Modo, M. M. J. J. (2011). Magnetic Resonance Neuroimaging: Methods and Protocols. New York, NY: Humana Press.
21. Caba, M., Silver, R., Gonzalez-Mariscal, G., Jimenez, A., and Beyer, C. (1996). Oxytocin and vasopressin immunoreactivity in rabbit hypo-thalamus during estrus, late pregnancy, and postpartum. Brain Res. 720, 7-16.
22. Cameron, H. A., and Gould, E. (1994). Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 61, 203-209.
23. Cameron, H. A., and McKay, R. D. (1999). Restoring production of hippocampal neurons in old age. Nat. Neurosci. 2, 894-897.
24. Cameron, H. A., and Mckay, R. D. (2001). Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol. 435, 406-417.
25. Campbell, J. C., Laugero, K. D., Van Westerhuyzen, J. A., Hostetler, C. M., Cohen, J. D., and Bales, K. L. (2009). Costs of pair-bonding and paternal care in male prairie voles (Micro-tus ochrogaster). Physiol. Behav. 98, 367-373.
26. Carter, C. S., Witt, D. M., Manock, S. R., Adams, K. A., Bahr, J. M., and Carlstead, K. (1989). Hormonal correlates of sexual behavior and ovulation in male-induced and postpartum estrus in female prairie voles. Physiol. Behav. 46, 941-948.
27. Cherng, C. G., Lin, P. S., Chuang, J. Y., Chang, W. T., Lee, Y. S., Kao, G. S., Lai, Y. T., and Yu, L. (2011). Presence of conspecifics and their odor-impregnated objects reverse stress-decreased neurogenesis in mouse dentate gyrus. J. Neurochem. 112, 1138-1146.
28. Christie, B. R., and Cameron, H. A. (2006). Neurogenesis in the adult hippocampus. Hippocampus 16, 199-207.
29. Clelland, C. D., Choi, M., Romberg, C., Clemenson, G. D. Jr., Fragniere, A., Tyers, P., Jessberger, S., Saksida, L. M., Barker, R. A., Gage, F. H., and Bussey, T. J. (2009). A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325, 210-213.
30. Cohen-Parsons, M., and Carter, C. S. (1987). Males increase serum estrogen and estrogen receptor binding in brain of female voles. Physiol. Behav. 39, 309-314.
31. Cooper-Kuhn, C. M., and Kuhn, H. G. (2002). Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain. Brain Res. Dev. Brain Res.134,13-21.
32. Coras, R., Siebzehnrubl, F. A., Pauli, E., Huttner, H. B., Njunting, M., Kobow, K., Villmann, C., Hahnen, E., Neuhuber, W., Weigel, D., Buch-felder, M., Stefan, H., Beck, H., Steindler, D. A., and Blumcke, I. (2010). Low proliferation and differentiation capacities of adult hip-pocampal stem cells correlate with memory dysfunction in humans. Brain 133, 3359-3372.
33. Corona, R., Larriva-Sahd, J., and Pare-des, R. G. (2011). Paced-mating increases the number of adult new born cells in the internal cellular (granular) layer of the accessory olfactory bulb. PLoS ONE 6, e19380. doi:10.1371/journal.pone.0019380
34. Cowley, J. J., and Brooksbank, B. W. (1991). Human exposure to putative pheromones and changes in aspects of social behaviour. J. Steroid Biochem. Mol. Biol. 39, 647-659.
35. Curtis, M. A., Kam, M., Nannmark, U., Anderson, M. F., Axell, M. Z., Wikkelso, C., Holtas, S., Van Roon-Mom, W. M., Bjork-Eriksson, T., Nordborg, C., Frisen, J., Dragunow, M., Faull, R. L., and Eriksson, P. S. (2007). Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension. Science 315, 1243-1249.
36. Curtis, R. (1995). Stress, personality and illness: the move from generality to specificity in current research trends. Ir. J. Psychol. 16, 299-321.
37. Czeh, B., Michaelis, T., Watanabe, T., Frahm, J., De Biurrun, G., Van Kampen, M., Bartolomucci, A., and Fuchs, E. (2001). Stress-induced changes in cerebral metabolites, hip-pocampal volume, and cell proliferation are prevented by antide-pressant treatment with tianeptine. Proc. Natl. Acad. Sci. U.S.A. 98, 12796-12801.
38. Czeh, B., Muller-Keuker, J. I., Rygula, R., Abumaria, N., Hiemke, C., Domenici, E., and Fuchs, E. (2007). Chronic social stress inhibits cell proliferation in the adult medial pre-frontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment. Neuropsychopharmacology 32, 1490-1503.
39. Czeh, B., Welt, T., Fischer, A. K., Erhardt, A., Schmitt, W., Muller, M. B., Toschi, N., Fuchs, E., and Keck, M. E. (2002). Chronic psychosocial stress and concomitant repetitive transcra-nial magnetic stimulation: effects on stress hormone levels and adult hip-pocampal neurogenesis. Biol. Psychiatry 52, 1057-1065.
40. Danzer, S. C. (2008). Postnatal and adult neurogenesis in the development of human disease. Neuroscientist. 14, 446-458.
41. Dayer, A. G., Cleaver, K. M., Abouan-toun, T., and Cameron, H. A. (2005). New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J. Cell Biol. 168, 415-427.
42. Dewsbury, D. A. (1975). Diversity and adaptation in rodent copulatory behavior. Science 190, 947-954.
43. Drapeau, E., Mayo, W., Aurousseau, C., Le Moal, M., Piazza, P. V., and Abrous, D. N. (2003). Spatial memory performances of aged rats in the water maze predict levels of hip-pocampal neurogenesis. Proc. Natl. Acad. Sci. U.S.A. 100, 14385-14390.
44. Dulac, C., and Torello, A. T. (2003). Molecular detection of pheromone signals in mammals: from genes to behaviour. Nat. Rev. Neurosci. 4, 551-562.
45. Ellickson, P. L., Collins, R. L., and Bell, R. M. (1999). Adolescent use of illicit drugs other than marijuana: how importantissocial bonding and for which ethnic groups? Subst. Use Misuse 34, 317-346.
46. Eng, L. F., Ghirnikar, R. S., and Lee, Y. L. (2000). Glial fibrillary acidic protein: GFAP-thirty-one years (1969- 2000). Neurochem. Res. 25, 1439-1451.
47. Eriksson, P. S., Perfilieva, E., Bjork-Eriksson, T., Alborn, A. M., Nord-borg, C., Peterson, D. A., and Gage, F. H. (1998). Neurogenesis in the adult human hippocampus. Nat. Med. 4, 1313-1317.
48. Erskine, M. S., and Kornberg, E. (1992). Acute luteinizing hormone and prolactin responses to paced mating stimulation in the estrous female rat. J. Neuroendocrinol. 4, 173-179.
49. Falconer, E. M., and Galea, L. A. (2003). Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult rats. Brain Res. 975, 22-36.
50. Fietz, J., and Dausmann, K. H. (2003). Costs and potential benefits of parental care in the nocturnal fat-tailed dwarf lemur (Cheirogaleus medius). Folia Primatol. 74,246-258.
51. Flanagan-Cato, L. M., Calizo, L. H., Griffin, G. D., Lee, B. J., and Whis-ner, S. Y. (2006). Sexual behaviour induces the expression of activity-regulated cytoskeletal protein and modifies neuronal morphology in the female rat ventromedial hypo-thalamus. J. Neuroendocrinol. 18, 857-864.
52. Fowler, C. D., Freeman, M. E., and Wang, Z. (2003). Newly proliferated cells in the adult male amygdala are affected by gonadal steroid hormones. J. Neurobiol. 57, 257-269.
53. Fowler, C. D., Johnson, F., and Wang, Z. (2005). Estrogen regulation of cell proliferation and distribution of estrogen receptor-alpha in the brains of adult female prairie and meadow voles. J. Comp. Neurol. 489, 166-179.
54. Fowler, C. D., Liu, Y., Ouimet, C., and Wang, Z. (2002). The effects of social environment on adult neurogenesis in the female prairie vole. J. Neurobiol. 51, 115-128.
55. Fowler, C. D., Liu, Y., and Wang, Z. (2008). Estrogen and adult neuroge-nesis in the amygdala and hypothal-amus. Brain Res. Rev. 57, 342-351.
56. Francis, F., Koulakoff, A., Boucher, D., Chafey, P., Schaar, B., Vinet, M. C., Friocourt, G., Mcdonnell, N., Reiner, O., Kahn, A., Mcconnell, S. K., Berwald-Netter, Y., Denoulet, P., and Chelly, J. (1999). Dou-blecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Neuron 23, 247-256.
57. Furuta, M., and Bridges, R. S. (2005). Gestation-induced cell proliferation in the rat brain. Brain Res. Dev. Brain Res. 156, 61-66.
58. Galand, P., and Degraef, C. (1989). Cyclin/PCNA immunostaining as an alternative to tritiated thymidine pulse labelling for marking S phase cells in paraffin sections from animal and human tissues. Cell Tissue Kinet. 22, 383-392.
59. Galea, L. A., and McEwen, B. S. (1999). Sex and seasonal differences in the rate of cell proliferation in the dentate gyrus of adult wild meadow voles. Neuroscience 89, 955-964.
60. Ganem, G., Ginane, C., Ostrowski, M. F., and Orth, A. (2005). Assessment of mate preference in the house mouse with reference to investigations on assortative mating. Biol. J. Linn. Soc. Lond. 84, 461-471.
61. Ganong, W. F. (1997). Review of Medical Physiology. Stamford, CT: Appleton & Lange.
62. Garland, H. O., Atherton, J. C., Baylis, C., Morgan, M. R., and Milne, C. M. (1987). Hormone profiles for progesterone, oestradiol, prolactin, plasma renin activity, aldosterone and corticosterone during pregnancy and pseudopregnancy in two strains of rat: correlation with renal studies. J. Endocrinol. 113, 435-444.
63. Garthe, A., Behr, J., and Kemper-mann, G. (2009). Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PLoS ONE 4, e5464. doi:10.1371/journal.pone.0005464
64. Getz, L. L., and McGuire, B. (1993). A comparison of living singly and in male-female pairs in the prairie vole, Microtus ochrogaster. Ethology 94, 265-278.
65. Gheusi, G., Ortega-Perez, I., Murray, K., and Lledo, P. M. (2009). A niche for adult neurogenesis in social behavior. Behav. Brain Res. 200, 315-322.
66. Glasper, E. R., and Gould, E. (2010). Sexual experience enhances adult neurogenesis in the dentate gyrus and affects cognitive and anxietylike behavior in the aging rat. Soc. Neurosci. Abstr. 40, 205.1 (LLL18).
67. Glasper, E. R., Kozorovitskiy, Y., Pavlic, A., and Gould, E. (2011). Paternal experience suppresses adult neuro-genesis without altering hippocam-pal function in Peromyscus californicus. J. Comp. Neurol. 519,2271-2281.
68. Gould, E. (2007). How widespread is adult neurogenesis in mammals? Nat. Rev. Neurosci. 8, 481-488.
69. Gould, E., Cameron, H. A., Daniels, D. C., Woolley, C. S., and Mcewen, B. S. (1992). Adrenal hormones suppress cell division in the adult rat dentate gyrus. J. Neurosci. 12, 3642-3650.
70. Gould, E., Mcewen, B. S., Tanapat, P., Galea, L. A., and Fuchs, E. (1997). Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J. Neurosci. 17, 2492-2498.
71. Gould, E., Tanapat, P., Mcewen, B. S., Flugge, G., and Fuchs, E. (1998). Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc. Natl. Acad. Sci. U.S.A. 95, 3168-3171.
72. Gould, E., Woolley, C. S., Cameron, H. A., Daniels, D. C., and Mcewen, B. S. (1991). Adrenal steroids regulate postnatal development of the rat dentate gyrus: II. Effects of glu-cocorticoids and mineralocorticoids on cell birth. J. Comp. Neurol. 313, 486-493.
73. Grattan, D. R. (2001). The actions of prolactin in the brain during pregnancy and lactation. Prog. Brain Res. 133, 153-171.
74. Grattan, D. R., and Averill, R. L. (1990). Effect of ovarian steroids on a nocturnal surge of prolactin secretion that precedes parturition in the rat. Endocrinology 126, 1199-1205.
75. Grattan, D. R., Steyn, F. J., Kokay, I. C., Anderson, G. M., and Bunn, S. J. (2008). Pregnancy-induced adaptation in the neuroendocrine control of prolactin secretion. J. Neuroendocrinol. 20, 497-507.
76. Graziano, F., Bonino, S., and Cattelino, E. (2009). Links between maternal and paternal support, depressive feelings and social and academic self-efficacy in adolescence. Eur. J. Dev. Psychol. 6, 241-257.
77. Green, A. D., and Galea, L. A. (2008). Adult hippocampal cell proliferation is suppressed with estrogen withdrawal after a hormone-simulated pregnancy. Horm. Behav. 54, 203-211.
78. Gross, C. G. (2000). Neurogenesis in the adult brain: death of a dogma. Nat. Rev. Neurosci. 1, 67-73.
79. Grote, H. E., and Hannan, A. J. (2007). Regulators of adult neurogenesis in the healthy and diseased brain. Clin. Exp. Pharmacol. Physiol. 34, 533-545.
80. Gurley, L. R., Walters, R. A., and Tobey, R. A. (1974). Cell cycle-specific changes in histone phosphorylation associated with cell proliferation and chromosome condensation. J. Cell Biol. 60, 356-364.
81. Hawken, P. A., Jorre, T. J., Rodger, J., Esmaili, T., Blache, D., and Martin, G. B. (2009). Rapid induction of cell proliferation in the adult female ungulate brain (Ovisaries) associated with activation of the reproductive axis by exposure to unfamiliar males. Biol. Reprod. 80, 1146-1151.
82. Hersen, M. (2006). Clinician's Handbook of Adult Behavioral Assessment. Boston: Elsevier Academic Press.
83. House, J. S., Landis, K. R., and Umber-son, D. (1988). Social relationships and health. Science 241, 540-545.
84. Huang, L., and Bittman, E. L. (2002). Olfactory bulb cells generated in adult male golden hamsters are specifically activated by exposure to estrous females. Horm. Behav. 41, 343-350.
85. Huang, L., Devries, G. J., and Bittman, EL. (1998). Photoperiod regulates neuronal bromodeoxyuridine labeling in the brain of a seasonally breeding mammal. J. Neurobiol. 36, 410-420.
86. Huber, G., and Matus, A. (1984). Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2,in rat brain. J. Neurosci. 4, 151-160.
87. Hull, E. M., and Rodriguez-Manzo, G. (2009). "Male sexual behavior," in Hormones, Brain and Behavior, 2nd Edn, eds D. W. Pfaff, A. P. Arnold, A. M. Etgen, S. E. Fahrbach, and R. T. Rubin (San Diego: Academic Press), 5-65.
88. Jankord, R., and Herman, J. P. (2008). Limbic regulation of hypothalamo-pituitary-adrenocortical function during acute and chronic stress. Ann. N. Y. Acad. Sci. 1148, 64-73.
89. Jessberger, S., Clark, R. E., Broadbent, N. J., Clemenson, G. D. Jr., Consiglio, A., Lie, D. C., Squire, L. R., and Gage, F.H. (2009). Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recogni tion memory in adult rats. Learn. Mem. 16, 147-154.
90. Kam, M., Curtis, M. A., Mcglashan, S. R., Connor, B., Nannmark, U., and Faull, R. L. (2009). The cellular composition and morphological organization of the rostral migratory stream in the adult human brain. J. Chem. Neuroanat. 37, 196-205.
91. Kavaliers, M., Choleris, E., and Pfaff, D. W. (2005). Recognition and avoidance of the odors of parasitized conspecifics and predators: differential genomic correlates. Neurosci. Biobehav. Rev. 29, 1347-1359.
92. Kee, N., Sivalingam, S., Boonstra, R., and Wojtowicz, J. M. (2002). The utility of Ki-67 and BrdU as prolifera-tive markers of adult neurogenesis. J. Neurosci. Methods 115, 97-105.
93. Kee, N., Teixeira, C.M., Wang, A.H., and Frankland, P. W. (2007). Imaging activation of adult-generated granule cells in spatial memory. Nat. Protoc. 2, 3033-3044.
94. Keeney, A., Jessop, D. S., Harbuz, M. S., Marsden, C. A., Hogg, S., and Blackburn-Munro, R. E. (2006). Differential effects of acute and chronic social defeat stress on hypothalamic-pituitary-adrenal axis function and hippocampal serotonin release in mice. J. Neuroendocrinol. 18, 330-338.
95. Kempermann, G., Kuhn, H. G., and Gage, F. H. (1997). More hippocam-pal neurons in adult mice living in an enriched environment. Nature 386, 493-495.
96. Kiecolt-Glaser, J. K., and Newton, T. L. (2001). Marriage and health: his and hers. Psychol. Bull. 127, 472-503.
97. Kim, S. K., Hwang, I. K., Yoo, K. Y., Yoo, D. Y., Bae, E., Lee, C. H., Choi, J. H., Choi, J. W., Seong, J. K., Yoon, Y. S., and Won, M. H. (2010). Pregnancy inhibits cell proliferation and neuroblast differentiation without neu-ronal damage in the hippocampal dentate gyrus in C57BL/6N mice. Brain Res. 1315, 25-32.
98. Kinsley, C. H., Trainer, R., Stafisso-Sandoz, G., Quadros, P., Marcus, L. K., Hearon, C., Meyer, E. A., Hester, N., Morgan, M., Kozub, F. J., and Lambert, K. G. (2006). Motherhood and the hormones of pregnancy modify concentrations of hip-pocampal neuronal dendritic spines. Horm. Behav. 49, 131-142.
99. Knoth, R., Singec, I., Ditter, M., Pan-tazis, G., Capetian, P., Meyer, R. P., Horvat, V., Volk, B., and Kemper-mann, G. (2010). Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years. PLoS ONE 5, e8809. doi:10.1371/journal.pone.0008809
100. Kokoeva, M. V., Yin, H., and Flier, J. S. (2005). Neurogenesis in the hypo-thalamus of adult mice: potential role in energy balance. Science 310, 679-683.
101. Kollack-Walker, S., and Newman, S. W. (1997). Mating-induced expression of c-fos in the male Syrian hamster brain: role of experience, pheromones, and ejaculations. J. Neurobiol. 32, 481-501.
102. Kozorovitskiy, Y., and Gould, E. (2004). Dominance hierarchy influences adult neurogenesis in the dentate gyrus. J. Neurosci. 24, 6755-6759.
103. Larsen, C. M., Kokay, I. C., and Grat-tan, D. R. (2008). Male pheromones initiate prolactin-induced neuroge-nesis and advance maternal behavior in female mice. Horm. Behav. 53, 509-517.
104. Leasure, J. L., and Decker, L. (2009). Social isolation prevents exercise-induced proliferation of hippocam-pal progenitor cells in female rats. Hippocampus 19, 907-912.
105. Lee, R. M., and Robbins, S. B. (1998). The relationship between social connectedness and anxiety, self-esteem, and social identity. J. Couns. Psychol. 45, 338-345.
106. Lemaire, V., Koehl, M., Le Moal, M., and Abrous, D. N. (2000). Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc. Natl. Acad. Sci. U.S.A. 97, 11032-11037.
107. Leuner, B., Caponiti, J. M., and Gould, E. (2012). Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids. Hippocampus 22, 861-868.
108. Leuner, B., Glasper, E. R., and Gould, E. (2010a). Parenting and plasticity. Trends Neurosci. 33, 465-473.
109. Leuner, B., Glasper, E. R., and Gould, E. (2010b). Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones. PLoS ONE 5, e11597. doi:10.1371/jour-nal.pone.0011597
110. Leuner, B., Mirescu, C., Noiman, L., and Gould, E. (2007). Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids. Hippocampus 17, 434-442.
111. Levy, F., Gheusi, G., and Keller, M. (2011). Plasticity of the parental brain: a case for neurogenesis. J. Neuroendocrinol. 23, 984-993.
112. Lieberwirth, C., Liu, Y., Jia, X., and Wang, Z. (2012). Social isolation impairs adult neurogenesis in the limbic system and alters behaviors in female prairie voles. Horm. Behav. doi:10.1016/j.yhbeh.2012.03.005
113. Lightman, S. L. (2008). The neuroen-docrinology of stress: a never ending story. J. Neuroendocrinol. 20, 880-884.
114. Lillard, L. A., and Waite, L. J. (1995). Til death do us part - marital disruption and mortality. Am. J. Sociol. 100, 1131-1156.
115. Lin, D. Y., Zhang, S. Z., Block, E., and Katz, L. C. (2005). Encoding social signals in the mouse main olfactory bulb. Nature 434, 470-477.
116. Lin, S. H., Kiyohara, T., and Sun, B. (2003). Maternal behavior: activation of the central oxytocin receptor system in parturient rats? Neuroreport 14, 1439-1444.
117. Liu, Y., Curtis, J. T., Fowler, C. D., Meredith, M., and Wang, Z. X. (2007). Chemosensory cues affect adult neu-rogenesis in the amygdala of prairie voles in a sex-specific manner. Soc. Behav. Neuroendocrinol Abstr. 11, P1.26.
118. Lledo, P. M., and Saghatelyan, A. (2005). Integrating new neurons into the adult olfactory bulb: joining the network, life-death decisions, and the effects of sensory experience. Trends Neurosci. 28, 248-254.
119. Lonstein, J. S., and De Vries, G. J. (1999). Comparison of the parental behavior of pair-bonded female and male prairie voles (Microtus ochrogaster). Physiol. Behav. 66, 33-40.
120. Lonstein, J. S., and De Vries, G. J. (2000). Sex differences in the parental behavior of rodents. Neurosci. Biobehav. Rev. 24, 669-686.
121. Lucassen, P. J., Meerlo, P., Naylor, A. S., Van Dam, A. M., Dayer, A. G., Fuchs, E., Oomen, C. A., and Czeh, B. (2010). Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: implications for depression and antidepressant action. Eur. Neuropsychopharmacol. 20, 1-17.
122. Luzzati, F., De Marchis, S., Fasolo, A., and Peretto, P. (2006). Neurogenesis in the caudate nucleus of the adult rabbit. J. Neurosci. 26, 609-621.
123. Maestripieri, D. (2001). Is there mother-infant bonding in primates? Dev. Rev. 21, 93-120.
124. Mak, G. K., Enwere, E. K., Gregg, C., Pakarainen, T., Poutanen, M., Huh-taniemi, I., and Weiss, S. (2007). Male pheromone-stimulated neuro-genesis in the adult female brain: possible role in mating behavior. Nat. Neurosci. 10, 1003-1011.
125. Mak, G. K., and Weiss, S. (2010). Paternal recognition of adult offspring mediated by newly generated CNS neurons. Nat. Neurosci. 13, 753-758.
126. Martinez, I., and Paredes, R. G. (2001). Only self-paced mating is rewarding in rats of both sexes. Horm. Behav. 40, 510-517.
127. Martinez, M., Calvo-Torrent, A., and Pico-Alfonso, M. A. (1998). Social defeat and subordination as models of social stress in laboratory rodents: a review. Aggress. Behav. 24, 241-256.
128. Mas, M. (1995). Neurobiological correlates of masculine sexual behavior. Neurosci. Biobehav. Rev. 19, 261-277.
129. Mazzucco, C. A., Lieblich, S. E., Bing-ham, B. I., Williamson, M. A., Viau, S V., and Galea, L. A. (2006). Both estrogen receptor alpha and estrogen receptor beta agonists enhance cell proliferation in the dentate gyrus of adult female rats. Neuroscience 141, 1793-1800.
130. McEwen, B. S. (1994). Corticosteroids and hippocampal plasticity. Ann. N. Y. Acad. Sci. 746, 134-142.
131. McEwen, B. S. (2010). Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling. Ann. N. Y. Acad. Sci. 1204(Suppl.), E38-E59.
132. Meisel, R. L., and Mullins, A. J. (2006). Sexual experience in female rodents: cellular mechanisms and functional consequences. Brain Res. 1126, 56-65.
133. Memberg, S. P., and Hall, A. K. (1995). Dividing neuron precursors express neuron-specific tubulin. J. Neurobiol. 27, 26-43.
134. Migaud, M., Batailler, M., Segura, S., Duittoz, A., Franceschini, I., and Pillon, D. (2010). Emerging new sites for adult neurogenesis in the mammalian brain: a comparative study between the hypo-thalamus and the classical neurogenic zones. Eur. J. Neurosci. 32, 2042-2052.
135. Ming, G. L., and Song, H. (2005). Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 28, 223-250.
136. Minturn, J. E., Geschwind, D. H., Fryer, H. J., and Hockfield, S. (1995). Early postmitotic neurons transiently express TOAD-64, a neural specific protein. J. Comp. Neurol. 355, 369-379.
137. Mirescu, C., and Gould, E. (2006). Stress and adult neurogenesis. Hippocampus 16, 233-238.
138. Mitra, R., Sundlass, K., Parker, K. J., Schatzberg, A. F., and Lyons, D. M. (2006). Social stress-related behavior affects hippocampal cell proliferation in mice. Physiol. Behav. 89, 123-127.
139. Mogi, K., Nagasawa, M., and Kikusui, T. (2011). Developmental consequences and biological significance of mother-infant bonding. Prog. Neuropsychopharmacol. Biol. Psychiatry 35, 1232-1241.
140. Mullen, R. J., Buck, C. R., and Smith, A. M. (1992). NeuN,a neuronal specific nuclear protein in vertebrates. Development 116, 201-211.
141. Nagy, A. I., Ormerod, B. K., Maz-zucco, C., and Galea, L. A. M. (2005). Estradiol-induced enhancement in cell proliferation is mediated through estrogen receptors in the dentate gyrus of adult female rats. Drug Dev. Res. 66, 142-149.
142. Nowak, R., Porter, R. H., Levy, F., Orgeur, P., and Schaal, B. (2000). Role of mother-young interactions in the survival of offspring in domestic mammals. Rev. Reprod. 5, 153-163.
143. Numan, M., and Insel, T. R. (2003). The Neurobiology of Parental Behavior. New York: Springer-Verlag.
144. Nyuyki, K. D., Waldherr, M., Baeuml, S., and Neumann, I. D. (2011). Yes, I am ready now: differential effects of paced versus unpaced mating on anxiety and central oxytocin release in female rats. PLoS ONE 6, e23599. doi:10.1371/journal.pone.0023599
145. Oatridge, A., Holdcroft, A., Saeed, N., Hajnal, J. V., Puri, B. K., Fusi, L., and Bydder, G. M. (2002). Change in brain size during and after pregnancy: study in healthy women and women with preeclampsia. AJNR Am. J. Neuroradiol. 23, 19-26.
146. Oboti, L., Savalli, G., Giachino, C., De Marchis, S., Panzica, G. C., Fasolo, A., and Peretto, P. (2009). Integration and sensory experience-dependent survival of newly-generated neurons in the accessory olfactory bulb of female mice. Eur. J. Neurosci. 29, 679-692.
147. Okano, H. J., and Darnell, R. B. (1997). A hierarchy of Hu RNA binding proteins in developing and adult neurons. J. Neurosci. 17, 3024-3037.
148. Okuda, H., Tatsumi, K., Makinodan, M., Yamauchi, T., Kishimoto, T., and Wanaka, A. (2009). Environmental enrichment stimulates progenitor cell proliferation in the amygdala. J. Neurosci. Res. 87, 3546-3553.
149. Ormerod, B. K., and Galea, L. A. (2001). Reproductive status influences cell proliferation and cell survival in the dentate gyrus of adult female meadow voles: a possible regulatory role for estradiol. Neuroscience 102, 369-379.
150. Ormerod, B. K., and Galea, L. A. (2003). Reproductive status influences the survival of new cells in the dentate gyrus of adult male meadow voles. Neurosci. Lett. 346, 25-28.
151. Ormerod, B. K., Lee, T. T., and Galea, L. A. (2003). Estradiol initially enhances but subsequently suppresses (via adrenal steroids) granule cell proliferation in the dentate gyrus of adult female rats. J. Neurobiol. 55, 247-260.
152. Ormerod, B. K., Lee, T. T., and Galea, L. A. (2004). Estradiol enhances neu-rogenesis in the dentate gyri of adult male meadow voles by increasing the survival of young granule neurons. Neuroscience 128, 645-654.
153. Pawluski, J. L., Barakauskas, V. E., and Galea, L. A. (2010). Pregnancy decreases oestrogen receptor alpha expression and pyknosis, but not cell proliferation or survival, in the hippocampus. J. Neuroendocrinol. 22 248-257.
154. Pawluski, J. L., Brummelte, S., Barha, C. K., Crozier, T. M., and Galea, L. A. (2009). Effects of steroid hormones on neurogenesis in the hippocampus of the adult female rodent during the estrous cycle, pregnancy, lactation and aging. Front. Neuroendocrinol. 30, 343-357.
155. Pereira, A. C., Huddleston, D. E., Brick-man, A. M., Sosunov, A. A., Hen, R., Mckhann, G. M., Sloan, R., Gage F. H., Brown, T. R., and Small, S. A. (2007). An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc. Natl. Acad Sci. U.S.A. 104, 5638-5643.
156. Pfaus, J. G., and Heeb, M. M. (1997). Implications of immediate-early gene induction in the brain following sexual stimulation of female and male rodents. Brain Res. Bull. 44 397-407.
157. Powers, J. B. (1970). Hormonal control of sexual receptivity during the estrous cycle of the rat. Physiol. Behav. 5, 831-835.
158. Properi, E. (1997). Mutliple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control. Prog. Cell Cycle Res. 3 193-210.
159. Ramony Cajal, S. (1928). Degeneration & Regeneration of the Nervous System. London: Oxford University Press.
160. Rasia-Filho, A. A., Fabian, C., Rigoti, K. M., and Achaval, M. (2004). Influence of sex, estrous cycle and motherhood on dendritic spine density in the rat medial amygdala revealed by the Golgi method. Neuroscience 126 839-847.
161. Raymond, A. D., Kucherepa, N. N., Fisher, K. R., Halina, W. G., and Partlow, G. D. (2006). Neurogenesis of oxytocin-containing neurons in the paraventricular nucleus (PVN) of the female pig in 3 reproductive states: puberty gilts, adult gilts and lactating sows. Brain Res. 1102 44-51.
162. Rochefort, C., Gheusi, G., Vincent, J. D. and Lledo, P. M. (2002). Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory. J. Neurosci. 22, 2679-2689
163. Rolls, A., Schori, H., London, A., and Schwartz, M. (2008). Decrease in hippocampal neurogenesis during pregnancy: a link to immunity. Mol. Psychiatry 13, 468-469.
164. Rosenblatt, J. S. (1967). Non-hormonal basis of maternal behavior in the rat. Science 156, 1512-1514.,
165. Ruscio, M. G., Sweeny, T. D., Hazelton, J. L., Suppatkul, P., Boothe, E., and Carter, C. S. (2008). Pup exposure elicits hippocampal cell proliferation in the prairie vole. Behav. Brain Res. 187, 9-16.
166. Russell, J. A., Douglas, A. J., and Ingram, C. D. (2001). Brain preparations for maternity - adaptive changes in behavioral and neuroendocrine sys tems during pregnancy and lactation. An overview. Prog. Brain Res., 133, 1-38.
167. Sanchez, S., Pelaez, F., Gil-Burmann, C., and Kaumanns, W. (1999). Costs of infant-carrying in the cotton-top. tamarin (Saguinus oedipus). Am. J. Primatol. 48, 99-111.
168. Schmechel, D. E., Brightman, M. W., and Marangos, P. J. (1980). Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation. Brain Res. 190, 195-214.
169. Scholzen, T., and Gerdes, J. (2000). The Ki-67 protein: from the known and the unknown. J. Cell. Physiol. 182, 311-322.
170. Seeringer, A., Walter, M., Kirchheiner, J., and Abler, B. (2010). Sex in the brain - imaging neural correlates of sexual stimulation. Nervenheilkunde 29, 468-474
171. Seki, T., and Arai, Y. (1993). Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat. J. Neurosci. 13, 2351-2358.
172. Shaikh, A. A. (1971). Estrone and estradiol levels in the ovarian venous blood from rats during the estrous,cycle and pregnancy. Biol. Reprod. 5, 297-307.
173. Shingo, T., Gregg, C., Enwere, E., Fujikawa, H., Hassam, R., Geary, C., Cross, J. C., and Weiss, S. (2003). Pregnancy-stimulated neu- rogenesis in the adult female fore- brain mediated by prolactin. Science 299, 117-120.,
174. Shors, T. J., Miesegaes, G., Beylin, A., Zhao, M., Rydel, T., and Gould, E. (2001). Neurogenesis in the adult is involved in the forma tion of trace memories. Nature 410, 372-376.
175. Sierra, A., Encinas, J. M., and Maletic Savatic, M. (2011). Adult human neurogenesis: from microscopy to magnetic resonance imaging. Front. Neurosci. 5:47. doi:10.3389/fnins.2011.00047
176. Silverstein, M., and Bengtson, V. L. (1991). Do close parent-child rela tions reduce the mortality risk of older parents? J. Health Soc. Behav. 32, 382-395.
177. Simon, M., Czeh, B., and Fuchs, E.(2005).Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress. Brain Res. 1049, 244-248.
178. Sivan, E., Whittaker, P. G., Sinha, D., Homko, C. J., Lin, M., Reece, E. A., and Boden, G. (1998). Leptin in human pregnancy: the relationship with gestational hormones. Am. J. Obstet. Gynecol. 179, 1128-1132.
179. Smith, A. S., and Wang, Z. (2011). Salubrious effects of oxytocin on social stress-induced deficits. Horm. Behav. 61, 320-330.
180. Smith, M. T., Pencea, V., Wang, Z., Luskin, M. B., and Insel, T. R. (2001). Increased number of BrdU-labeled neurons in the rostral migratory stream of the estrous prairie vole. Horm. Behav. 39, 11-21.
181. Snyder, J. S., and Cameron, H. A. (2011). Couldadulthippocampalneurogen-esis be relevant for human behavior? Behav. Brain Res. 227, 384-390.
182. Spalding, K. L., Bhardwaj, R. D., Buch-holz, B. A., Druid, H., and Frisen, J. (2005). Retrospective birth dating of cells in humans. Cell 122, 133-143.
183. Spritzer, M. D., and Galea, L. A. (2007). Testosterone and dihy-drotestosterone, but not estradiol, enhance survival of new hippocam-pal neurons in adult male rats. Dev. Neurobiol. 67, 1321-1333.
184. Spritzer, M. D., Ibler, E., Inglis, W., and Curtis, M. G. (2011). Testosterone and social isolation influence adult neurogenesis in the dentate gyrus of male rats. Neuroscience 195, 180-190.
185. Spritzer, M. D., Weinberg, A., Viau, V., and Galea, L. A. (2009). Prior sexual experience increases hippocam-pal cell proliferation and decreases risk assessment behavior in response to acute predator odor stress in the male rat. Behav. Brain Res. 200, 106-112.
186. Staples, L. G. (2010). Predator odor avoidance as a rodent model of anxiety: learning-mediated consequences beyond the initial exposure. Neurobiol. Learn. Mem. 94, 435-445.
187. Steptoe, A. (1991). Invited review. The links between stress and illness. J. Psychosom. Res. 35, 633-644.
188. Stoeber, K., Tlsty, T. D., Happerfield, L., Thomas, G. A., Romanov, S., Bobrow, L., Williams, E. D., and Williams, G. H. (2001). DNA replication licensing and human cell proliferation. J. Cell Sci. 114, 2027-2041.
189. Stranahan, A. M., Khalil, D., and Gould, E. (2006). Social isolation delays the positive effects of running on adult neurogenesis. Nat. Neurosci. 9, 526-533.
190. Tung, Y. H., Shin, M. S., Cho, S., Baik, H. H., Jin, B. K., Chang, H. K., Lee, E. K., and Kim, C. J. (2010). Depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus. Neurosci. Lett. 470, 86-90.
191. Tabori, N. E., Stewart, L. S., Znamen-sky, V., Romeo, R. D., Alves, S. E., Mcewen, B. S., and Milner, T. A. (2005). Ultrastructural evidence that androgen receptors are located at extranuclear sites in the rat hip-pocampal formation. Neuroscience 130, 151-163.
192. Tanapat, P., Hastings, N. B., and Gould, E. (2005). Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose- and time-dependent manner. J. Comp. Neurol. 481, 252-265.
193. Tanapat, P., Hastings, N. B., Reeves, A. J., and Gould, E. (1999). Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat. J. Neurosci. 19, 5792-5801.
194. Tanapat, P., Hastings, N. B., Rydel, T. A., Galea, L. A., and Gould, E. (2001). Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone-dependent mechanism. J. Comp. Neurol. 437, 496-504.
195. Tashiro, A., Makino, H., and Gage, F. H. (2007). Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. J. Neurosci. 27, 3252-3259.
196. Thomas, R. M., Hotsenpiller, G., and Peterson, D. A. (2007). Acute psychosocial stress reduces cell survival in adult hippocampal neurogene-sis without altering proliferation. J. Neurosci. 27, 2734-2743.
197. Thomas, R. M., Urban, J. H., and Peterson, D. A. (2006). Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult rat hippocampus. Exp. Neurol. 201, 308-315.
198. Tirindelli, R., Dibattista, M., Pifferi, S., and Menini, A. (2009). From pheromones to behavior. Physiol. Rev. 89, 921-956.
199. Townsend, K. C., and McWhirter, B. T. (2005). Connectedness: a review of the literature with implications for counseling, assessment, and research. J. Couns. Dev. 83, 191-201.
200. Tsigos, C., and Chrousos, G. P. (2002). Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J. Psychosom. Res. 53, 865-871.
201. Turnbull, A. C., Patten, P. T., Flint, A. P., Keirse, M. J., Jeremy, J. Y., and Anderson, A. B. (1974). Significant fall in progesterone and rise in oestradiol levels in human peripheral plasma before onset of labour. Lancet 1, 101-103.
202. Valenstein, E. S., and Young, W. C. (1955). An experiential factor influencing the effectiveness of testosterone propionate in eliciting sexual behavior in male guinea pigs. Endocrinology 56, 173-177.
203. van Bokhoven, P., Oomen, C. A., Hoogendijk, W. J., Smit, A. B., Lucassen, P. J., and Spijker, S. (2011). Reduction in hippocampal neurogenesis after social defeat is long-lasting and responsive to late antidepressant treatment. Eur. J. Neurosci. 33, 1833-1840.
204. van der Hart, M. G., Czeh, B., De Biurrun, G., Michaelis, T., Watan-abe, T., Natt, O., Frahm, J., and Fuchs, E. (2002). Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume. Mol. Psychiatry 7, 933-941.
205. van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., and Gage, F. H. (2002). Functional neurogenesis in the adult hippocampus. Nature 415, 1030-1034.
206. van Praag, H., Shubert, T., Zhao, C., Van Gage, F. H. (2005). Exercise enhance learning and hippocampal neuroge nesis in aged mice. J. Neurosci. 25 8680-8685.
207. Veenema, A. H., and Neumann, I. D (2008). "Central vasopressin an oxytocin release: regulation of com plex social behaviours," in Advance in Vasopressin and Oxytocin: From Genes to Behaviour to Disease, eds I. J A. Urban, J. P. H. Burbach, and D. D Wied (Amsterdam: Elsevier Scienc Bv), 261-276.
208. Waldherr, M., and Neumann, I. D (2007). Centrally released oxytoci mediates mating-induced anxiolysi in male rats. Proc. Natl. Acad. Sci U.S.A. 104, 16681-16684.
209. Wallace, K. J., and Rosen, J. B. (2000) Predator odor as an unconditione fear stimulus in rats: elicitation o freezing by trimethylthiazoline, component of fox feces. Behav. Neurosci. 114, 912-922.
210. Waltz, M., Badura, B., Pfaff, H., and Schott, T. (1988). Marriage an the psychological consequences o a heart attack: a longitudinal stud of adaptation to chronic illnes after 3 years. Soc. Sci. Med. 27 149-158.
211. Wang, C., Liu, F., Liu, Y. Y., Zhao, C. H., You, Y., Wang, L., Zhang, J., Wei, B, Ma, T., Zhang, Q., Zhang, Y., Chen R., Song, H., and Yang, Z. (2011) Identification and characterizatio of neuroblasts in the subventricula zone and rostral migratory stream o the adult human brain. Cell Res. 21 1534-1550.
212. Weickert, C. S., Webster, M. J., Colvin S. M., Herman, M. M., Hyde, T. M., Weinberger, D. R., and Kleinman, J. E. (2000). Localization of epidermal growth factor receptors and putative neuroblasts in human subependy-mal zone. J. Comp. Neurol. 423, 359-372.
213. Weiland, N. G., Orikasa, C., Hayashi, S., and Mcewen, B. S. (1997). Distribution and hormone regulation of estrogen receptor immunoreac-tive cells in the hippocampus of male and female rats. J. Comp. Neurol. 388, 603-612.
214. Westenbroek, C., Den Boer, J. A., Veen-huis, M., and Ter Horst, G. J. (2004). Chronic stress and social housing differentially affect neurogenesis in male and female rats. Brain Res. Bull. 64, 303-308.
215. Williams, J. R., Catania, K. C., and Carter, C. S. (1992). Development of partner preferences in female prairie voles (Microtus ochrogaster): the role of social and sexual experience. Horm. Behav. 26, 339-349.
216. Winberg, J. (2005). Mother and newborn baby: mutual regulation of physiology and behavior - a selective review. Dev. Psychobiol. 47, 217-229.
217. Winner, B., Kohl, Z., and Gage, F. H. (2011). Neurodegenerative disease and adult neurogenesis. Eur. J. Neu-rosci. 33, 1139-1151.
218. Wong, E.Y., and Herbert, J. (2005). Roles of mineralocorticoid and glucocor-ticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. Eur. J. Neurosci. 22, 785-792.
219. Yap, J. J., Takase, L. F., Kochman, L. J., Fornal, C. A., Miczek, K. A., and Jacobs, B. L. (2006). Repeated brief social defeat episodes in mice: effects on cell proliferation in the dentate gyrus. Behav. Brain Res. 172, 344-350.
220. Young, K. A., Gobrogge, K. L., Liu, Y., and Wang, Z. (2011). The neurobiology of pair bonding: insights from a socially monogamous rodent. Front. Neuroendocrinol. 32, 53-69.
221. Young, L. J., and Wang, Z. (2004). The neurobiology of pair bonding. Nat. Neurosci. 7, 1048-1054.
222. Zheng, W., Zhuge, Q., Zhong, M., Chen, G., Shao, B., Wang, H., Mao, X., Xie, L., and Jin, K. (2011). Neurogene-sis in adult human brain after traumatic brain injury. J. Neurotrauma. doi:10.1212/s00222-009-0987-6