Leptin in human pregnancy: The relationship with gestational hormones

American Journal of Obstetrics and Gynecology

Volumn 179, Issue 5, 1998, Pages 1128-1132

  Sivan, E ^a   Whittaker, P G ^a   Sinha, D ^a   Homko, C J ^a   Lin, M ^a   Reece, E A ^a   Boden, G ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3T3 L1 Adipocytes; Gestational hormones; Leptin; Pregnancy

Indexed keywords

LEPTIN; PLACENTAL PEPTIDE HORMONE;

ADIPOCYTE; CESAREAN SECTION; CONFERENCE PAPER; FEMALE; FIRST TRIMESTER PREGNANCY; HORMONE BLOOD LEVEL; HUMAN; NORMAL HUMAN; PREGNANCY; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY;

EID: 0031757143     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(98)70118-8     Document Type: Conference Paper

References (18)

1. Y Zhang R Proenca M Maffei M Barone L Leopold JM Friedman Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432
2. DL Coleman Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice Diabetologia 14 1978 141 148
3. RV Considine MK Sinha ML Heiman A Kriauciunas TW Stephens MR Nyce Serum immunoreactive leptin concentrations in normal-weight and obese humans N Engl J Med 334 1996 292 295
4. M Maffei J Halaas E Rayussin RE Pratley GM Lee Y Zhang Leptin levels in human and rodent: measurement of plasma leptin and ob mRNA in obese and weight-reduced subjects Nat Med 1 1995 1155 1161
5. LA Campfield FJ Smith Y Guisez R Devos P. Burn Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks Science 269 1995 546 549
6. MW Schwartz RJ Seeley LA Campfield P Burn DG Baskin Identification of targets of leptin action in rat hypothalamus J Clin Invest 98 1996 1001 1106
7. RV Considine EL Considine CJ Williams TM Hyde JF Caro The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations Diabetes 19 1996 992 994
8. FF Chehab ME Lim L. Ronghua Correction of the sterility defect in homozygous obese female mice by treatment with human recombinant leptin Nat Genet 12 1996 318 320
9. IA Barash CC Cheung DS Weigle R Hongping EB Kagigting JL Kuijper Leptin is a metabolic signal to the reproductive system Endocrinology 137 1996 3144 3147
10. RS Ashima J Dushay EM Flier D Prabakaran JS Flier Leptin accelerates the onset of puberty in normal female mice J Clin Invest 99 1997 391 395
11. FF Chehab K Mounzih R Lu ME Lim Early onset of reproductive function in normal female mice treated with leptin Science 275 1997 88 90
12. RS Ashima D Prabakaran C Mantzoros D Qu B Lowell EM Flier Role of leptin in the neuroendocrine response to fasting Nature 382 1996 250 252
13. C Mantzoros JS Flier AD Rogol A longitudinal assessment of hormonal and physical alterations during normal puberty in boys v rising leptin levels may signal the onset of puberty J Clin Endocrinol Metab 82 1997 1066 1070
14. H Masuzaki H Ogawa N Sagawa K Hosada T Matsumoto H Mise Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans Nat Med 3 1997 1029 1033
15. M Rosenbaum M Nicolson J Hirsch SB Heymsfield D Gallagher F Chu Effects of gender, body composition, and menopause on plasma concentrations of leptin J Clin Endocrinol Metab. 81 1996 3424 3427
16. MO Aspillaga PG Whittaker A Taylor T. Lind Some new aspects of the endocrinological response to pregnancy Br J Obstet Gynaecol 90 1983 596 603
17. P Leroy S Dessolin P Villageois BC Moon JM Friedman G Ailhaud Expression of ob gene in adipose cells: regulation by insulin J Biol Chem 271 1996 2365 2368
18. G Boden X Chen Kolaczynski M. Polansky Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects J Clin Invest 100 1997 1107 1113