Inhibition of microglial activity alters spinal wide dynamic range neuron discharge and reduces microglial Toll-like receptor 4 expression in neuropathic rats

Clinical and Experimental Pharmacology and Physiology

Volumn 42, Issue 7, 2015, Pages 772-779

  Nazemi, Samad ^a,b   Manaheji, Homa ^b   Noorbakhsh, Syyed Mohammad ^b   Zaringhalam, Jalal ^b   Sadeghi, Mehdi ^c   Mohammad Zadeh, Mohammad ^a   Haghparast, Abbas ^b  

^a SABZEVAR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c BUSHEHR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Hyperalgesia; Microglia; Neuropathic pain; Toll like receptor 4; WDR neuron

Indexed keywords

MINOCYCLINE; SODIUM CHLORIDE; TOLL LIKE RECEPTOR 4; TLR4 PROTEIN, RAT;

ADULT; ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL ACTIVITY; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; ELECTROSTIMULATION; EXPERIMENTAL NEUROPATHY; EXPERIMENTAL PAIN; HARGREAVES TEST; HIND PAW; HYPERALGESIA; MALE; MECHANICAL STIMULATION; MICROGLIA; MICROGLIAL ACTIVATION; NERVE CELL INHIBITION; NERVE CELL MEMBRANE POTENTIAL; NEUROPATHIC PAIN; NONHUMAN; PROTEIN EXPRESSION; RAT; REPEATED DRUG DOSE; SPINAL CORD NERVE CELL; TEMPERATURE RELATED PHENOMENA; THERMAL HYPERALGESIA; THERMAL STIMULATION; WESTERN BLOTTING; WIDE DYNAMIC RANGE NEURON; WISTAR RAT; ANIMAL; DRUG EFFECTS; EVOKED RESPONSE; GENE EXPRESSION REGULATION; LIGATION; METABOLISM; NERVE CELL; NEURALGIA; PATHOLOGY; SPINAL CORD DORSAL HORN; TIME;

ANIMALS; CONSTRICTION; EVOKED POTENTIALS; GENE EXPRESSION REGULATION; HYPERALGESIA; MALE; MICROGLIA; MINOCYCLINE; NEURALGIA; NEURONS; RATS; RATS, WISTAR; SPINAL CORD DORSAL HORN; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 84933576112     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12414     Document Type: Article

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