메뉴 건너뛰기




Volumn 23, Issue 6, 2002, Pages 755-759

The consequences of methylmercury exposure on interactive functions between astrocytes and neurons

Author keywords

Astrocyte; Cystine; Glutamate; Glutathione; Methylmercury; Transport

Indexed keywords

ASPARTIC ACID; CATALASE; CYSTINE; FREE RADICAL; GAMMA GLUTAMYLTRANSFERASE; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN PEROXIDE; METHYLMERCURY; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE;

EID: 0036905468     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-813X(01)00076-6     Document Type: Conference Paper
Times cited : (67)

References (42)
  • 1
    • 0027291920 scopus 로고
    • Ultrastructural evidence that mercuric chloride lowers the threshold for glutamate neurotoxicity in an organotypic culture of rat cerebellum
    • Albrecht J. Ultrastructural evidence that mercuric chloride lowers the threshold for glutamate neurotoxicity in an organotypic culture of rat cerebellum. Neurosci Lett 1993;158:155-8.
    • (1993) Neurosci Lett , vol.158 , pp. 155-158
    • Albrecht, J.1
  • 2
    • 0035830692 scopus 로고    scopus 로고
    • Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes but not in neurons
    • Allen JW, Shanker G, Aschner M. Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes but not in neurons. Brain Res 2001a;891:148-57.
    • (2001) Brain Res , vol.891 , pp. 148-157
    • Allen, J.W.1    Shanker, G.2    Aschner, M.3
  • 3
    • 0035947014 scopus 로고    scopus 로고
    • 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase
    • 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain Res 2001b;902:92-100.
    • (2001) Brain Res , vol.902 , pp. 92-100
    • Allen, J.W.1    Mutkus, L.A.2    Aschner, M.3
  • 4
    • 0026483404 scopus 로고
    • Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity
    • Ali SF, LeBel CP, Bond SC. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. NeuroToxicology 1992;13:637-48.
    • (1992) NeuroToxicology , vol.13 , pp. 637-648
    • Ali, S.F.1    LeBel, C.P.2    Bond, S.C.3
  • 5
    • 0029894261 scopus 로고    scopus 로고
    • Methylmercury in astrocytes - What possible significance?
    • Aschner M. Methylmercury in astrocytes - What possible significance? NeuroToxicology 1996;17:93-106.
    • (1996) NeuroToxicology , vol.17 , pp. 93-106
    • Aschner, M.1
  • 6
    • 0023748960 scopus 로고
    • Uptake of methylmercury in the rat brain: Effects of amino acids
    • Aschner M, Clarkson TW. Uptake of methylmercury in the rat brain: Effects of amino acids. Brain Res 1988;462:31-9.
    • (1988) Brain Res , vol.462 , pp. 31-39
    • Aschner, M.1    Clarkson, T.W.2
  • 8
    • 0028063294 scopus 로고
    • Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures
    • Aschner M, Mullaney KJ, Wagoner D, Lash LH, Kimelberg HK. Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures. Brain Res 1994;664:133-40.
    • (1994) Brain Res , vol.664 , pp. 133-140
    • Aschner, M.1    Mullaney, K.J.2    Wagoner, D.3    Lash, L.H.4    Kimelberg, H.K.5
  • 10
    • 0018963749 scopus 로고
    • Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture
    • Bannai S, Kitamura E. Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J Biol Chem 1980;255:2372-6.
    • (1980) J Biol Chem , vol.255 , pp. 2372-2376
    • Bannai, S.1    Kitamura, E.2
  • 11
    • 0027948358 scopus 로고
    • Increases in the number of reactive glia in the visual cortex of Macaca fascicularis following subclinical long-term methyl mercury exposure
    • Charleston JS, Bolender RP, Mottet NK, Body RL, Vahter ME, Burbacher TM. Increases in the number of reactive glia in the visual cortex of Macaca fascicularis following subclinical long-term methyl mercury exposure. Toxicol Appl Pharmacol 1994;129:196-206.
    • (1994) Toxicol Appl Pharmacol , vol.129 , pp. 196-206
    • Charleston, J.S.1    Bolender, R.P.2    Mottet, N.K.3    Body, R.L.4    Vahter, M.E.5    Burbacher, T.M.6
  • 12
    • 0029005110 scopus 로고
    • Autometall-ographic determination of inorganic mercury distribution in the cortex of the calcarine sulcus of the monkey Macaca fascicularis following long-term subclinical exposure to methylmercury and mercuric chloride
    • Charleston JS, Body RL, Mottet NK, Vahter ME, Burbacher TM. Autometall-ographic determination of inorganic mercury distribution in the cortex of the calcarine sulcus of the monkey Macaca fascicularis following long-term subclinical exposure to methylmercury and mercuric chloride. Toxicol Appl Pharmacol 1995;132:325-33.
    • (1995) Toxicol Appl Pharmacol , vol.132 , pp. 325-333
    • Charleston, J.S.1    Body, R.L.2    Mottet, N.K.3    Vahter, M.E.4    Burbacher, T.M.5
  • 13
    • 0029943154 scopus 로고    scopus 로고
    • Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure
    • Charleston JS, Body RL, Bolender RP, Mottet NK, Vahter ME, Burbacher TM. Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure. NeuroToxicology 1996;17:127-38.
    • (1996) NeuroToxicology , vol.17 , pp. 127-138
    • Charleston, J.S.1    Body, R.L.2    Bolender, R.P.3    Mottet, N.K.4    Vahter, M.E.5    Burbacher, T.M.6
  • 14
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW. Excitotoxic cell death. J Neurobiol 1992;23:1261-76.
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 15
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993;262:689-95.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 17
    • 0029318857 scopus 로고
    • Mechanisms of use of extracellular glutathione by lung epithelial cells and pulmonary artery endothelial cells
    • Deneke SM, Susanto I, Vogel KA, Williams CE, Lawrence RA. Mechanisms of use of extracellular glutathione by lung epithelial cells and pulmonary artery endothelial cells. Am J Resp Cell Mol Biol 1995;12:662-8.
    • (1995) Am J Resp Cell Mol Biol , vol.12 , pp. 662-668
    • Deneke, S.M.1    Susanto, I.2    Vogel, K.A.3    Williams, C.E.4    Lawrence, R.A.5
  • 18
    • 0033555806 scopus 로고    scopus 로고
    • Synthesis of the antioxi dant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione
    • Dringen R, Pfeiffer B, Hamprecht B. Synthesis of the antioxi dant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci 1999;19:562-9.
    • (1999) J Neurosci , vol.19 , pp. 562-569
    • Dringen, R.1    Pfeiffer, B.2    Hamprecht, B.3
  • 19
    • 0024416697 scopus 로고
    • Accumulation of methylmercury and inorganic mercury in the brain
    • Friberg L, Mottet NK. Accumulation of methylmercury and inorganic mercury in the brain. Biol Trace Elem Res 1989;21:201-6.
    • (1989) Biol Trace Elem Res , vol.21 , pp. 201-206
    • Friberg, L.1    Mottet, N.K.2
  • 21
    • 0000380025 scopus 로고    scopus 로고
    • Minamata disease and other mercury syndromes
    • Chang LW, editor. Boca Raton (FL): CRC Press
    • Hamada R, Osame M. Minamata disease and other mercury syndromes. In: Chang LW, editor. Toxicology of Metals. Boca Raton (FL): CRC Press; 1996. p. 337-51.
    • (1996) Toxicology of Metals , pp. 337-351
    • Hamada, R.1    Osame, M.2
  • 22
    • 0014681286 scopus 로고
    • Biological methylation of mercury in aquatic organisms
    • Jensen S, Jernelov A. Biological methylation of mercury in aquatic organisms. Nature 1969;223:753-4.
    • (1969) Nature , vol.223 , pp. 753-754
    • Jensen, S.1    Jernelov, A.2
  • 23
    • 0030010607 scopus 로고    scopus 로고
    • Methylmercury-induced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists
    • Kim SU, Park ST, Lim KT, Chung YT. Methylmercury-induced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists. NeuroToxicology 1996;17:37-45.
    • (1996) NeuroToxicology , vol.17 , pp. 37-45
    • Kim, S.U.1    Park, S.T.2    Lim, K.T.3    Chung, Y.T.4
  • 24
    • 0031984256 scopus 로고    scopus 로고
    • Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: Preference for cystine
    • Kranich O, Dringen R, Sandberg M, Hamprecht B. Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: Preference for cystine. Glia 1998;22:11-8.
    • (1998) Glia , vol.22 , pp. 11-18
    • Kranich, O.1    Dringen, R.2    Sandberg, M.3    Hamprecht, B.4
  • 25
    • 0027233049 scopus 로고
    • Glial-neuronal interactions: The relevance to neurotoxic mechanisms
    • LoPachin RM, Aschner M. Glial-neuronal interactions: The relevance to neurotoxic mechanisms. Toxicol Appl Pharmacol 1994;118:141-58.
    • (1994) Toxicol Appl Pharmacol , vol.118 , pp. 141-158
    • LoPachin, R.M.1    Aschner, M.2
  • 27
    • 0027512435 scopus 로고
    • Reduced methylmercury accumulation in a methylmercury-resistant rat pheochromocytoma PC12 cell line
    • Miura K, Clarkson TW. Reduced methylmercury accumulation in a methylmercury-resistant rat pheochromocytoma PC12 cell line. Toxicol Appl Pharmacol 1993;118:39-45.
    • (1993) Toxicol Appl Pharmacol , vol.118 , pp. 39-45
    • Miura, K.1    Clarkson, T.W.2
  • 29
    • 0022411669 scopus 로고
    • 3H-L-glutamate binding sites in rat brain as determined by quantitative autoradiography
    • 3H-L-glutamate binding sites in rat brain as determined by quantitative autoradiography. J Neurosci 1985;5:2909-19.
    • (1985) J Neurosci , vol.5 , pp. 2909-2919
    • Monaghan, D.T.1    Cotman, C.W.2
  • 32
    • 0014856188 scopus 로고
    • Biotransformation of methylmercury salts in the rat studied by specific determination of inorganic mercury
    • Norseth T, Clarkson TW. Biotransformation of methylmercury salts in the rat studied by specific determination of inorganic mercury. Biochem Pharmacol 1970;19:2775-83.
    • (1970) Biochem Pharmacol , vol.19 , pp. 2775-2783
    • Norseth, T.1    Clarkson, T.W.2
  • 33
    • 0013986322 scopus 로고
    • Neuropathological studies on organic mercury poisonings with special reference to the staining and distribution of mercury granules
    • Oyake Y, Tanaka M, Kubo H, Cichibu H. Neuropathological studies on organic mercury poisonings with special reference to the staining and distribution of mercury granules. Adv Neurol Sci 1966;10:744-50.
    • (1966) Adv Neurol Sci , vol.10 , pp. 744-750
    • Oyake, Y.1    Tanaka, M.2    Kubo, H.3    Cichibu, H.4
  • 34
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J, Miura K, Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem 1993;61:1672-6.
    • (1993) J Neurochem , vol.61 , pp. 1672-1676
    • Sagara, J.1    Miura, K.2    Bannai, S.3
  • 35
    • 0028100383 scopus 로고
    • Bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line
    • Sarafian TA, Vartavarian L, Kane DJ, Bredesen DE, Verity MA. Bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line. Toxicol Lett 1994;74:149-55.
    • (1994) Toxicol Lett , vol.74 , pp. 149-155
    • Sarafian, T.A.1    Vartavarian, L.2    Kane, D.J.3    Bredesen, D.E.4    Verity, M.A.5
  • 37
    • 0017395621 scopus 로고
    • Pathology of fetal Minamata disease - The effects of methylmercury on intrauterine life of human beings
    • Takeuchi T. Pathology of fetal Minamata disease - The effects of methylmercury on intrauterine life of human beings. Pediatrician 1977;6:69-78.
    • (1977) Pediatrician , vol.6 , pp. 69-78
    • Takeuchi, T.1
  • 38
    • 0020338425 scopus 로고
    • Pathology of Minamata disease with special reference to its pathogenesis
    • Takeuchi T. Pathology of Minamata disease with special reference to its pathogenesis. Acta Pathol Jpn 1982;32:73-99.
    • (1982) Acta Pathol Jpn , vol.32 , pp. 73-99
    • Takeuchi, T.1
  • 40
    • 0014412088 scopus 로고
    • Synthesis on methylmercury compounds by extracts of methanogenic bacterium
    • Wood JM, Kennedy FS, Rosen CE. Synthesis on methylmercury compounds by extracts of methanogenic bacterium. Nature 1968;220:173-4.
    • (1968) Nature , vol.220 , pp. 173-174
    • Wood, J.M.1    Kennedy, F.S.2    Rosen, C.E.3
  • 41
    • 0028840790 scopus 로고
    • Demethylation of methylmercury in different brain sites of Macaca fascicularis monkeys during long-term subclinical methyl mercury exposure
    • Vahter ME, Mottet NK, Friberg LT, Lind SB, Charleston SJ, Burbacher TM. Demethylation of methylmercury in different brain sites of Macaca fascicularis monkeys during long-term subclinical methyl mercury exposure. Toxicol Appl Pharmacol 1995;134:273-84.
    • (1995) Toxicol Appl Pharmacol , vol.134 , pp. 273-284
    • Vahter, M.E.1    Mottet, N.K.2    Friberg, L.T.3    Lind, S.B.4    Charleston, S.J.5    Burbacher, T.M.6
  • 42
    • 0008266881 scopus 로고    scopus 로고
    • Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity
    • Yao CP, Allen JW, Mutkus LA, Xu SB, Tan KH, Aschner M. Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity. Brain Res 2000;855:32-8.
    • (2000) Brain Res , vol.855 , pp. 32-38
    • Yao, C.P.1    Allen, J.W.2    Mutkus, L.A.3    Xu, S.B.4    Tan, K.H.5    Aschner, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.