ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis

Journal of Experimental and Clinical Cancer Research

Volumn 34, Issue 1, 2015, Pages

  Qin, Li Sen ^a,b   Jia, Pi Feng ^c   Zhang, Zhi Qing ^a   Zhang, Shi Ming ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Sixth People's Hospital of Yancheng   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Cyclophilin D and p53; Glioma; Mitochondrial permeability transition pore (mPTP); Programmed necrosis; Salinomycin

Indexed keywords

ACETYLCYSTEINE; CYCLOPHILIN D; CYCLOSPORIN A; PROTEIN P53; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; SALINOMYCIN; SANGLIFEHRIN A; SMALL INTERFERING RNA; CYCLOPHILIN; PYRAN DERIVATIVE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; GLIOMA CELL; MITOCHONDRIAL PERMEABILITY; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; CHEMICALLY INDUCED; GENETICS; GLIOMA; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOPHILINS; GLIOMA; HUMANS; PYRANS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84933518128     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0174-1     Document Type: Article

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