Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species

Toxicology Letters

Volumn 222, Issue 2, 2013, Pages 139-145

  Zhou, Jin ^a   Li, Pu ^b   Xue, Xiaofeng ^a   He, Songbing ^a   Kuang, Yuting ^a   Zhao, Hong ^a   Chen, Shaoji ^a   Zhi, Qiaoming ^a   Guo, Xiaobo ^c  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cisplatin resistant; Reactive oxygen species; Salinomycin

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ALDH1A1 PROTEIN; ALDH1A3 PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; CD133 ANTIGEN; CD24 ANTIGEN; CISPLATIN; DIPEPTIDYL PEPTIDASE IV; GLUTATHIONE PEROXIDASE; HERMES ANTIGEN; KRUPPEL LIKE FACTOR 4; LACTATE DEHYDROGENASE; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SALINOMYCIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL CYCLE; CELL DEATH; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

APOPTOSIS; CISPLATIN-RESISTANT; REACTIVE OXYGEN SPECIES; SALINOMYCIN;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL MARKERS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; COLORECTAL NEOPLASMS; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; HUMANS; INHIBITORY CONCENTRATION 50; NEOPLASTIC STEM CELLS; OXIDATIVE STRESS; OXIDOREDUCTASES; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRANS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84882959995     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.07.022     Document Type: Article

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