Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization

Biochemical and Biophysical Research Communications

Volumn 413, Issue 1, 2011, Pages 80-86

  Kim, Kwang Youn ^a   Yu, Sun Nyoung ^a   Lee, Sun Yi ^b   Chun, Sung Sik ^c   Choi, Yong Lark ^d   Park, Yeong Min ^a   Song, Chung Seog ^e   Chatterjee, Bandana ^e   Ahn, Soon Cheol ^a,e,f  

^a Pusan National University School of Medicine   (South Korea)

^b Rural Development Administration   (South Korea)

^c International University of Korea   (South Korea)

^d Dong A University   (South Korea)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f Pusan National University   (South Korea)

Author keywords

Apoptosis; Mitochondrial membrane potential; N Acetylcysteine; PC 3 cells; Prostate cancer; Reactive oxygen species; Salinomycin

Indexed keywords

ACETYLCYSTEINE; ANDROGEN; CASPASE 3; CYTOCHROME C; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; SALINOMYCIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CELL STRAIN LNCAP; CONCENTRATION RESPONSE; CONTROLLED STUDY; EVOKED RESPONSE; HUMAN; HUMAN TISSUE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN TRANSPORT; TUMOR GROWTH; TUMOR RECURRENCE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; CYTOSOL; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRANS; REACTIVE OXYGEN SPECIES;

EID: 80052844878     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.054     Document Type: Article

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