Biodistribution and in vivo toxicity of aptamer-loaded gold nanostars

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 3, 2015, Pages 671-679

  Dam, Duncan Hieu M ^a   Culver, Kayla S B ^b   Kandela, Irawati ^a   Lee, Raymond C ^a   Chandra, Kavita ^b   Lee, Hyojin ^a   Mantis, Christine ^a   Ugolkov, Andrey ^a   Mazar, Andrew P ^a   Odom, Teri W ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Northwestern University   (United States)

Author keywords

Aptamer; Biodistribution; Gold nanoconstructs; Gold nanostars; Toxicity

Indexed keywords

CELL CULTURE; DISEASES; GOLD; MEDICINE; RATS; TUMORS;

ACUTE TOXICITY; APTAMERS; BIODISTRIBUTIONS; BREAST CANCER TUMORS; CANCER CELL LINES; G-QUADRUPLEXES; GOLD NANOSTARS; TUMOR ACCUMULATION;

TOXICITY;

APTAMER; GOLD NANOPARTICLE; GOLD NANOSTAR; GUANINE QUADRUPLEX; UNCLASSIFIED DRUG; GOLD; METAL NANOPARTICLE;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG RESPONSE; DRUG SYNTHESIS; FEMALE; FIBROSARCOMA; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM TOLERATED DOSE; NONHUMAN; PATHOLOGY; RAT; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT RESPONSE; TUMOR MODEL; ANIMAL; CHEMISTRY; DRUG SCREENING; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MOUSE; NUDE MOUSE; SEXUAL DEVELOPMENT; TUMOR CELL LINE;

RATTUS;

ANIMALS; APTAMERS, NUCLEOTIDE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FIBROSARCOMA; GOLD; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; METAL NANOPARTICLES; MICE; MICE, NUDE; RATS; SEX CHARACTERISTICS;

EID: 84933507494     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.10.005     Document Type: Article

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