Hyaluronan polymer length, grafting density, and surface poly(ethylene glycol) coating influence in vivo circulation and tumor targeting of hyaluronan-grafted liposomes

ACS Nano

Volumn 8, Issue 6, 2014, Pages 5423-5440

  Qhattal, Hussaini Syed Sha ^a   Hye, Tanvirul ^a   Alali, Amer ^a   Liu, Xinli ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

accelerated clearance; active tumor targeting; CD44; HA polymer length; hyaluronan liposomes; passive tumor targeting; PEG coating

Indexed keywords

BINDING ENERGY; CARDIOVASCULAR SYSTEM; GRAFTING (CHEMICAL); LIGANDS; LIPOSOMES; MOLECULAR BIOLOGY; PLASTIC COATINGS; POLYETHYLENE GLYCOLS; POLYMERS; TUMORS;

ACCELERATED CLEARANCE; CD44; HYALURONAN; POLYMER LENGTH; TUMOR TARGETING;

HYALURONIC ACID;

CD44 PROTEIN, HUMAN; HERMES ANTIGEN; HYALURONIC ACID; LIGAND; LIPID; LIPOSOME; MACROGOL DERIVATIVE;

ANIMAL; AREA UNDER THE CURVE; CANCER TRANSPLANTATION; CHEMISTRY; FEMALE; FLOW CYTOMETRY; HUMAN; LIGHT; MOUSE; NANOMEDICINE; NEOPLASMS; NUDE MOUSE; PHAGOCYTOSIS; PROCEDURES; RADIATION SCATTERING; SURFACE PROPERTY; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD44; AREA UNDER CURVE; CELL LINE, TUMOR; FEMALE; FLOW CYTOMETRY; HUMANS; HYALURONIC ACID; LIGANDS; LIGHT; LIPIDS; LIPOSOMES; MICE; MICE, NUDE; NANOMEDICINE; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHAGOCYTOSIS; POLYETHYLENE GLYCOLS; SCATTERING, RADIATION; SURFACE PROPERTIES;

EID: 84903472901     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn405839n     Document Type: Article

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