Tunicamycin promotes apoptosis in leukemia cells through ROS generation and downregulation of survivin expression

Apoptosis

Volumn 20, Issue 8, 2015, Pages 1087-1098

  Lim, Eun Jin ^a   Heo, Jeonghoon ^a   Kim, Young Ho ^a  

^a Kosin University   (South Korea)

Author keywords

Apoptosis; ER stress; ROS; Survivin

Indexed keywords

CASPASE 3; CYTOCHROME C; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SURVIVIN; TUNICAMYCIN; ANTINEOPLASTIC AGENT; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN KINASE INHIBITOR;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; U937 CELL LINE; CELL PROLIFERATION; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; METABOLISM;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL PROLIFERATION; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LEUKEMIA; MAP KINASE SIGNALING SYSTEM; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; TUNICAMYCIN; U937 CELLS;

EID: 84933179094     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-015-1135-z     Document Type: Article

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