-
1
-
-
0028912082
-
Recent progress in research on Tripterygium: A male antifertility plant
-
Zhen QS, Ye X and Wei ZJ: Recent progress in research on Tripterygium: a male antifertility plant. Contraception 51: 121-129, 1995.
-
(1995)
Contraception
, vol.51
, pp. 121-129
-
-
Zhen, Q.S.1
Ye, X.2
Wei, Z.J.3
-
2
-
-
0032433899
-
Antitumor activity of triptolide against cholangiocarcinoma growth in vitro and in hamsters
-
DOI 10.1016/S0304-3835(98)00222-5, PII S0304383598002225
-
Tengchaisri T, Chawengkirttikul R, Rachaphaew N, Reutrakul V, Sangsuwan R and Sirisinha S: Antitumor activity of triptolide against cholangiocarcinoma growth in vitro and in hamsters. Cancer Lett 133: 169-175, 1998. (Pubitemid 29069041)
-
(1998)
Cancer Letters
, vol.133
, Issue.2
, pp. 169-175
-
-
Tengchaisri, T.1
Chawengkirttikul, R.2
Rachaphaew, N.3
Reutrakul, V.4
Sangsuwan, R.5
Sirisinha, S.6
-
3
-
-
0032742443
-
Inhibitory effect of triptolide on platelet derived growth factor-A and coronary arteriosclerosis after heart transplantation
-
DOI 10.1016/S0041-1345(99)00539-4, PII S0041134599005394
-
Hachida M, Lu H, Zhang X, Saito S, Furutani Y, Matsuoka R, Hoshi H and Koyanagi H: Inhibitory effect of triptolide on platelet derived growth factor-A and coronary arteriosclerosis after heart transplantation. Transplant Proc 7: 2719-2723, 1999. (Pubitemid 29525625)
-
(1999)
Transplantation Proceedings
, vol.31
, Issue.7
, pp. 2719-2723
-
-
Hachida, M.1
Lu, H.2
Zhang, X.3
Saito, S.4
Furutani, Y.5
Matsuoka, R.6
Hoshi, H.7
Koyanagi, H.8
-
4
-
-
33745944185
-
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells
-
Carter BZ, Mak DH, Schober WD, McQueen T, Harris D, Estrov Z, Evans RL and Andreeff M: Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood 108: 630-637, 2006.
-
(2006)
Blood
, vol.108
, pp. 630-637
-
-
Carter, B.Z.1
Mak, D.H.2
Schober, W.D.3
McQueen, T.4
Harris, D.5
Estrov, Z.6
Evans, R.L.7
Andreeff, M.8
-
5
-
-
43949175494
-
Apoptosis
-
Cohen JJ: Apoptosis. Immunol Today 14: 126-130, 1993.
-
(1993)
Immunol Today
, vol.14
, pp. 126-130
-
-
Cohen, J.J.1
-
6
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White E: Life, death, and the pursuit of apoptosis. Genes Dev 10: 1-15, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 1-15
-
-
White, E.1
-
7
-
-
0027172322
-
Molecular regulation of apoptosis: Genetic controls on cell death
-
Williams GT and Smith CA: Molecular regulation of apoptosis: genetic controls on cell death. Cell 74: 777-779, 1993.
-
(1993)
Cell
, vol.74
, pp. 777-779
-
-
Williams, G.T.1
Smith, C.A.2
-
9
-
-
0842281645
-
Cell Death: Critical Control Points
-
DOI 10.1016/S0092-8674(04)00046-7
-
Danial NN and Korsmeyer SJ: Cell death: critical control points. Cell 116: 205-219, 2004. (Pubitemid 38167313)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
10
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
Desagher S, Osen-Sand A, Nichols A, Eskes R, Montessuit S, Lauper S, Maundrell K, Antonsson B and Martinou JC: Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 144: 891-901, 1999.
-
(1999)
J Cell Biol
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.C.9
-
11
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ: Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730, 2001.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
12
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
DOI 10.1101/gad.897601
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR and Thompson CB: BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15: 1481-1486, 2001. (Pubitemid 32552527)
-
(2001)
Genes and Development
, vol.15
, Issue.12
, pp. 1481-1486
-
-
Zong, W.-X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
13
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM and Huang DC: Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17: 393-403, 2005.
-
(2005)
Mol Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
14
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
DOI 10.1016/j.molcel.2005.02.003
-
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR and Newmeyer DD: BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17: 525-535, 2005. (Pubitemid 40269117)
-
(2005)
Molecular Cell
, vol.17
, Issue.4
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
Newmeyer, D.D.7
-
15
-
-
0038046166
-
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
-
DOI 10.1101/gad.1093903
-
Nijhawan D, Fang M, Traer E, Zhong Q, Gao W, Du F and Wang X: Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev 17: 1475-1486, 2003. (Pubitemid 36734705)
-
(2003)
Genes and Development
, vol.17
, Issue.12
, pp. 1475-1486
-
-
Nijhawan, D.1
Fang, M.2
Traer, E.3
Zhong, Q.4
Gao, W.5
Du, F.6
Wang, X.7
-
16
-
-
22244464818
-
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
-
Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM and Huang DC: Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev 19: 1294-1305, 2005.
-
(2005)
Genes Dev
, vol.19
, pp. 1294-1305
-
-
Willis, S.N.1
Chen, L.2
Dewson, G.3
Wei, A.4
Naik, E.5
Fletcher, J.I.6
Adams, J.M.7
Huang, D.C.8
-
17
-
-
44449110735
-
MCL-1 inhibits BAX in the absence of MCL-1/BAX Interaction
-
Germain M, Milburn J and Duronio V: MCL-1 inhibits BAX in the absence of MCL-1/BAX Interaction. J Biol Chem 283: 6384-6392, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 6384-6392
-
-
Germain, M.1
Milburn, J.2
Duronio, V.3
-
18
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams JM and Cory S: The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326, 1998. (Pubitemid 28406819)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
19
-
-
0037085778
-
Myeloid cell factor-1 is a critical survival factor for multiple myeloma
-
Zhang B, Gojo I and Fenton RG: Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood 99: 1885-1893, 2002.
-
(2002)
Blood
, vol.99
, pp. 1885-1893
-
-
Zhang, B.1
Gojo, I.2
Fenton, R.G.3
-
20
-
-
0344629380
-
Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
-
DOI 10.1159/000074483
-
Festjens N, van Gurp M, van Loo G, Saelens X and Vandenabeele P: Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death. Acta Haematologica 111: 7-27, 2004. (Pubitemid 37499952)
-
(2004)
Acta Haematologica
, vol.111
, Issue.1-2
, pp. 7-27
-
-
Festjens, N.1
Van Gurp, M.2
Van Loo, G.3
Saelens, X.4
Vandenabeele, P.5
-
21
-
-
33645287685
-
Akt/PKB signaling in cancer: A function in cell motility and invasion
-
Yoeli-Lerner M and Toker A: Akt/PKB signaling in cancer: a function in cell motility and invasion. Cell Cycle 5: 603-605, 2006.
-
(2006)
Cell Cycle
, vol.5
, pp. 603-605
-
-
Yoeli-Lerner, M.1
Toker, A.2
-
22
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G, Ouyang G and Bao S: The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 9: 59-71, 2005.
-
(2005)
J Cell Mol Med
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
23
-
-
33748063941
-
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F and Libra M: Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 46: 249-279, 2006.
-
(2006)
Adv Enzyme Regul
, vol.46
, pp. 249-279
-
-
McCubrey, J.A.1
Steelman, L.S.2
Abrams, S.L.3
Lee, J.T.4
Chang, F.5
Bertrand, F.E.6
Navolanic, P.M.7
Terrian, D.M.8
Franklin, R.A.9
D'Assoro, A.B.10
Salisbury, J.L.11
Mazzarino, M.C.12
Stivala, F.13
Libra, M.14
-
24
-
-
54049083409
-
Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells
-
Yang M, Huang J, Pan HZ and Jin J: Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells. Int J Mol Med 22: 489-496, 2008.
-
(2008)
Int J Mol Med
, vol.22
, pp. 489-496
-
-
Yang, M.1
Huang, J.2
Pan, H.Z.3
Jin, J.4
-
25
-
-
63549123206
-
Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation
-
Shi X, Jin Y, Cheng C, Zhang H, Zou W, Zheng Q, Lu Z, Chen Q, Lai Y and Pan J: Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation. Clin Cancer Res 15: 1686-1697, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1686-1697
-
-
Shi, X.1
Jin, Y.2
Cheng, C.3
Zhang, H.4
Zou, W.5
Zheng, Q.6
Lu, Z.7
Chen, Q.8
Lai, Y.9
Pan, J.10
-
26
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM: Caspases: the executioners of apoptosis. Biochem J 326: 1-16, 1997.
-
(1997)
Biochem J
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
27
-
-
14944384245
-
Apoptosis signaling in tumor therapy
-
Fulda S and Debatin KM: Apoptosis signaling in tumor therapy. Ann NY Acad Sci 1028: 150-156, 2004.
-
(2004)
Ann NY Acad Sci
, vol.1028
, pp. 150-156
-
-
Fulda, S.1
Debatin, K.M.2
-
28
-
-
8844263797
-
Targeting apoptosis pathways in cancer therapy
-
DOI 10.2174/1568009043332763
-
Fulda S and Debatin KM: Targeting apoptosis pathways in cancer therapy. Curr Cancer Drug Targets 4: 569-576, 2004. (Pubitemid 39536377)
-
(2004)
Current Cancer Drug Targets
, vol.4
, Issue.7
, pp. 569-576
-
-
Fulda, S.1
Debatin, K.-M.2
-
29
-
-
85047699682
-
Direct repression of the Mcl-1 promoter by E2F1
-
DOI 10.1038/sj/onc/1205157
-
Croxton R, Ma Y, Song L, Haura EB and Cress WD: Direct repression of the Mcl-1 promoter by E2F1. Oncogene 21: 1359-1369, 2002. (Pubitemid 34214501)
-
(2002)
Oncogene
, vol.21
, Issue.9
, pp. 1359-1369
-
-
Croxton, R.1
Ma, Y.2
Song, L.3
Haura, E.B.4
Cress, W.D.5
-
30
-
-
0037370472
-
Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway
-
Wang JM, Lai MZ and Yang-Yen HF: Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Mol Cell Biol 23: 1896-1909, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 18961909
-
-
Wang, J.M.1
Lai, M.Z.2
Yang-Yen, H.F.3
-
31
-
-
0032772367
-
The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
-
Wang JM, Chao JR, Chen W, Kuo ML, Yen JJ and Yang-Yen HF: The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol Cell Biol 19: 6195-6206, 1999. (Pubitemid 29399324)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.9
, pp. 6195-6206
-
-
Wang, J.U.-M.1
Chao, J.-R.2
Chen, W.3
Kuo, M.-L.4
Yen, J.J.-Y.5
Yang-Yen, H.-F.6
-
32
-
-
33646846666
-
Mcl-1 interacts with truncated bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis
-
DOI 10.1074/jbc.M505688200
-
Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G and Brady HJ: Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. J Biol Chem 281: 5750-5759, 2006. (Pubitemid 43847674)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.9
, pp. 5750-5759
-
-
Clohessy, J.G.1
Zhuang, J.2
De Boer, J.3
Gil-Gomez, G.4
Brady, H.J.M.5
|