Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains

Neurobiology of Aging

Volumn 36, Issue 5, 2015, Pages 1994-2003

  Zhu, Caihong ^a   Herrmann, Uli S ^a   Li, Bei ^a   Abakumova, Irina ^a   Moos, Rita ^a   Schwarz, Petra ^a   Rushing, Elisabeth J ^a   Colonna, Marco ^b   Aguzzi, Adriano ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Microglial activation; Neuroinflammation; Pathogenesis; Prion disease; TREM2

Indexed keywords

TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; FEMALE; MALE; MICROGLIA; MOUSE; NONHUMAN; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RISK FACTOR; TRANSGENIC MOUSE;

ANIMALS; GENE EXPRESSION; MEMBRANE GLYCOPROTEINS; MICE, TRANSGENIC; MICROGLIA; PHENOTYPE; PRION DISEASES; RECEPTORS, IMMUNOLOGIC; RISK FACTORS; UP-REGULATION;

EID: 84933177929     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.02.019     Document Type: Article

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