Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia

Neurobiology of Aging

Volumn 35, Issue 2, 2014, Pages 444.e1-444.e4

  Ruiz, Agustín ^a   Dols Icardo, Oriol ^b,c   Bullido, María J ^c,d,e   Pastor, Pau ^c,f,g   Rodríguez Rodríguez, Eloy ^c,h   López de Munain, Adolfo ^c,i   de Pancorbo, Marian M ⁱ   Pérez Tur, Jordi ^c,j   Álvarez, Victoria ^k   Antonell, Anna ^l   López Arrieta, Jesús ^e   Hernández, Isabel ^a   Tárraga, Lluís ^a   Boada, Mercè ^a,m   Lleó, Alberto ^b,c   Blesa, Rafael ^b,c   Frank García, Ana ^c,e   Sastre, Isabel ^c,d,e   Razquin, Cristina ^c,f   Ortega Cubero, Sara ^c,f,g   Lorenzo, Elena ^c,f   Sánchez Juan, Pascual ^c,h   Combarros, Onofre ^c,h   Moreno, Fermín ^c,i   Gorostidi, Ana ^c,i   Elcoroaristizabal, Xabier ⁱ   Baquero, Miquel ⁿ   Coto, Eliecer ^k   Sánchez Valle, Raquel ^l   Clarimón, Jordi ^b,c   more..

^a Fundacio ACE   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^f UNIVERSITY OF NAVARRA   (Spain)

^g UNIVERSITY CLINIC OF NAVARRA   (Spain)

^h HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

ⁱ UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^j INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^k HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^l HOSPITAL CLÍNIC   (Spain)

^m HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

ⁿ HOSPITAL UNIVERSITARIO LA FE   (Spain)

more..

Author keywords

Alzheimer's disease; Frontotemporal dementia; Genetic association; P.R47H; Rare variant; TREM2

Indexed keywords

AGED; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE MUTATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON SYNONYMOUS AMINO ACID SUBSTITUTION; ONSET AGE; PRIORITY JOURNAL; RECESSIVE GENE; RISK FACTOR; SPAIN; TREM2 GENE;

ALZHEIMER'S DISEASE; FRONTOTEMPORAL DEMENTIA; GENETIC ASSOCIATION; P.R47H; RARE VARIANT; TREM2;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; COHORT STUDIES; FEMALE; FRONTOTEMPORAL DEMENTIA; GENES, RECESSIVE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; META-ANALYSIS AS TOPIC; MIDDLE AGED; MULTICENTER STUDIES AS TOPIC; MUTATION; POLYMORPHISM, GENETIC; RECEPTORS, IMMUNOLOGIC; RISK FACTORS; SPAIN;

EID: 84887219737     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.08.011     Document Type: Article

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